Current Progress in Cancer Cell Signaling

Cancer is referred to as a type of disease characterized by the growth of aberrant cells that divide irrepressibly and have the capacity to invade and destroy normal body tissue. It has the potential to spread throughout the body. Cancer is caused by epigenetic and genetic changes which enable cells to proliferate and evade mechanisms that would usually control their migration and survival. These numerous changes map to signaling pathways that regulate cell growth and division, cell motility, cell fate and cell death. They can be interpreted in the context of larger signaling network distortions that fuel the progression of cancer, including inflammation, modifications to the tumor microenvironment and angiogenesis. The majority of cancers start in epithelial cells and manifest as carcinomas in organs like the breast, pancreas, lung, liver and skin. This book contains some path-breaking studies on cancer cell signaling. Those in search of information to further their knowledge will be greatly assisted by it.