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BIOANALYTICAL ESTIMATION OF IMIQUIMOD IN RABBIT PLASMA BY RP-HPLC

Om BIOANALYTICAL ESTIMATION OF IMIQUIMOD IN RABBIT PLASMA BY RP-HPLC

The present study focuses on the identification and estimation of drugs in the biological matrix using a sophisticated analytical technique also studying their pharmacokinetic parameters like half-lives and rates of elimination and their metabolites in blood. Imiquimod topical treats external warts around the genital and rectal areas called condyloma acuminatum. A direct relationship exists between the drug concentration at the bio-phase (site of action) and the concentration of the drug in plasma. A typical plasma drug concentration-time curve obtained after a single oral dose of a drug and showing various pharmacokinetic and pharmacodynamic parameters.

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  • Språk:
  • Engelska
  • ISBN:
  • 9786206145806
  • Format:
  • Häftad
  • Sidor:
  • 84
  • Utgiven:
  • 17. februari 2023
  • Mått:
  • 150x6x220 mm.
  • Vikt:
  • 143 g.
  Fri leverans
Leveranstid: 2-4 veckor
Förväntad leverans: 4. juni 2025

Beskrivning av BIOANALYTICAL ESTIMATION OF IMIQUIMOD IN RABBIT PLASMA BY RP-HPLC

The present study focuses on the identification and estimation of drugs in the biological matrix using a sophisticated analytical technique also studying their pharmacokinetic parameters like half-lives and rates of elimination and their metabolites in blood. Imiquimod topical treats external warts around the genital and rectal areas called condyloma acuminatum. A direct relationship exists between the drug concentration at the bio-phase (site of action) and the concentration of the drug in plasma. A typical plasma drug concentration-time curve obtained after a single oral dose of a drug and showing various pharmacokinetic and pharmacodynamic parameters.

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