Diagnosis and Treatment of Pain of Vertebral Origin
A practical reference guide, this work offers descriptions of methodological procedures used in ageing research. Methods and protocols are critically evaluated and the advantages and disadvantages of each technique are explored.
In Vivo MR Techniques in Drug Discovery and Development
This work recognizes that an understanding of variability in response is critical in accounting for interindividual variability in susceptibility. Models for incorporating measures of response variability in the risk assessment process are critically reviewed and illustrated with published data.
When prescribing drugs, physicians must look at the whole picture of the drug's benefits in relation to its side effects and possible toxicity. The aim of this handbook is to compile data which should optimize the clinician's decision making in selecting effective, low-risk drug treatments.
This work examines behavioural manifestations of neurological diseases in infancy and childhood, covering information needed for the recognition, understanding and treatment of such problems resulting from neurological conditions. The behavioural-cognitive manifestations of AIDS is also covered.
Covering regulatory requirements stipulated by the FDA, this book delineates the organization, planning, verification, and documentation activities and procedural controls required for compliance.
Covering the recently passed 45 CFR, and the parallel CFR 21 Part 11 and HIPAA regulations 160, 162, and 164, this book provides guidance for purchasing, installing, validating, and managing commercial off-the-shelf software data for collection and
Providing a thorough review of automated systems testing to meet the regulatory requirements of the FDA and MCA, this title focuses on software module, software integration, hardware, and system acceptance testing. It covers best practices in computer systems testing for the pharmaceutical and related healthcare manufacturing industries.
Written especially for the pharmaceutical industry professional, this volume addresses each part of the life-cycle of engineering change control. It covers issues in the EU and US and describes the operational requirements and responsibilities that ensure change controls are effectively applied and recorded.
What if you were suddenly in charge? After the initial excitement of a "battlefield promotion" wears off, you need to get in the trenches and get the job done. And if you are already in the trenches, you need quick access to information that will make your job easier.
As a current publication on immunodermatology, this revised third edition provides an overview of the skin immune system, a totally updated section on immunodermatological diseases, and includes six new chapters on key topics.
Volume 2 of this set contains the full text of the FDA regulations, EC and IPEC guidelines, and ISO/BSI standards referenced in the checklists furnished in Volume I.
The editors provide in-depth analysis of management issues and basic background information on reproductive biology and medicine needed by the technicians staffing and directing these ART labs.
Including coverage of systemic osteoporosis induced by steroid use, this collection of essays focuses on basic and clinical essentials of osteoporosis and the latest orthopaedic findings in applied research and surgical treatment.
This text provides information on the erect positioning of the patient, and presents radiographic positioning in chart and illustrated formats, as well as details on collimation, film size and placement. It also focuses on quality assurance.
Mayo Clinic Analgesic Pathway
Focusing on a traditionally less studied age group, that of prepubertal children, this book presents concentrated and selected information about the relationship among health and anthropometry, physical activity, motor ability, and motor development in children between the ages of eight and twelve.
Offering findings in basic science on the structure, biology, physiology, and pathophysiology of complement proteins and the therapeutic approaches towards the control of complement-mediated diseases. This book describes the molecular architecture of the complement system; details the structure of complement genes; and more.
Delineates steps for the formulation of liquid parenteral biopharmaceutical products. This book covers pathways for each phase as well as its purpose, function, and relation to other stages in the product development process. It is written by experts involved in advances in the pharmaceutical drug industry.
Introducing the advances in crystallography, nuclear magnetic resonance, molecular modeling techniques, and computational combinatorial chemistry. This book discusses protein structure-based design in optimizing HIV protease inhibitors and details the biochemical, genetic, and clinical data on HIV-1 reverse transcriptase; and more.
Recognizing the explosive growth in information on intravenous immunoglobulins (IVIGs). This book surveys all available literature on the employment of IVIG preparations in clinical practice from pharmacoeconomics and pharmacokinetics to prophylaxis and management of infectious and autoimmune diseases.
Offers information on specialized products such as emulsions, liposomes, polymers and polymeric pharmaceutical excipients. This volume explains the requirements for conducting clinical research and obtaining marketing approval for new drug products.
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