Böcker utgivna av Springer Verlag, Singapore

Tumor biology varies at different subsites in the oral cavity, and therefore carcinoma of the gingivo-buccal sulcus (also known as Indian cancer) behaves differently from carcinoma of the tongue. Oral cancer is very often diagnosed at an advanced stage with neck metastasis, and most cases have a guarded prognosis. Loco-regional recurrences are frequent and morbidity following treatment is considerable. However, results have improved in recent years, particularly in early and certain advanced stages, due to better imaging and case selection, improved surgical techniques, including those for reconstructive surgery, a multidisciplinary team approach and a better understanding of tumor biology and prognostic factors.This book comprehensively and systematically reviews all these aspects of diagnostic and therapeutic advances in oral cancer, particularly discussing early detection, epidemiology, chemoprevention and current research. Written by specialists whoare active leaders in basic sciences or clinical fields, the chapters address individual and collective issues in managing patients with oral cancer, and provide insights into various treatment approaches. The authors share their knowledge and experience and provide extensive literature sources to encourage clinicians to be flexible, innovative and help them make the best, educated decisions for individual patients.

Tumor biology varies at different subsites in the oral cavity, and therefore carcinoma of the gingivo-buccal sulcus (also known as Indian cancer) behaves differently from carcinoma of the tongue. Oral cancer is very often diagnosed at an advanced stage with neck metastasis, and most cases have a guarded prognosis. Loco-regional recurrences are frequent and morbidity following treatment is considerable. However, results have improved in recent years, particularly in early and certain advanced stages, due to better imaging and case selection, improved surgical techniques, including those for reconstructive surgery, a multidisciplinary team approach and a better understanding of tumor biology and prognostic factors.This book comprehensively and systematically reviews all these aspects of diagnostic and therapeutic advances in oral cancer, particularly discussing early detection, epidemiology, chemoprevention and current research. Written by specialists who are active leaders in basic sciences or clinical fields, the chapters address individual and collective issues in managing patients with oral cancer, and provide insights into various treatment approaches. The authors share their knowledge and experience and provide extensive literature sources to encourage clinicians to be flexible, innovative and help them make the best, educated decisions for individual patients.

This book introduces the clinical application of artificial liver system (ALS) in hepatic failure. It has been widely used in clinics aiming to provide temporary support of liver function while maintaining extra-hepatic function in patients with liver failure. This work comprehensively summarizes the progress of livers and artificial liver, for example, the principle and implementation of Li-ALS, cell transplantation and the combined application of artificial liver and liver transplantation. It will be helpful for clinicians to implement artificial liver treatment to save the lives of patients with hepatic failure.

This book is a practical manual for anti-COVID-19. It is not only with the reference to the result of modern medical science, patients¿ situation, but also take the deployment of medical resources into consideration. Content of this manual includes: Medical administration under emergent circumstances, protection and control of hospital infection, clinical practice guidance for diagnosis and therapy, the application of radiation for the examination, laboratory diagnosis, inhabitation of inflammatory cytokines crisis, plasma of patient in the recovery stage, and traditional Chinese medical science etcetera.Authors are from Union hospital, Tongji medical college in Wuhan city, who has first-hand experiences. This book is a collection and fusion of such experiences in fighting against epidemic infectious disease. It is a timely book for doctors who are fighting against COVID-19.

This open access book covers all aspects of minimally invasive glaucoma surgery (MIGS) and provides detailed information on each MIGS device, including its mechanism of action; patient selection; implantation techniques; post-operative management; and a review of the existing literature. Step-by-step descriptions are provided for the surgical technique used in implanting each MIGS device, accompanied by clear photographs of each surgical stage. Other areas covered include intra-operative gonioscopy (with tips on optimising the view of the anterior chamber angle) and the management of the intra-operative and post-operative complications. Essential information on the anatomy and physiology of the different aqueous outflow pathways is also included.A separate chapter addresses the introduction of MIGS globally, including the consideration of different reimbursement environments and the different types of glaucoma, e.g. angle closure glaucoma. This book will assist both glaucoma surgeons and general ophthalmologists in overcoming the learning curve involved in performed MIGS, by providing valuable and practical clinical pearls

This book focuses on the representation of dermatological diseases in pigmented skin, fills an important gap in the literature, and facilitates better dermatological diagnosis when dealing with patients of various ethnicities. It discusses over 400 diseases and their representations with the help of over 2000 high-quality images and illustrations. This book elaborates on each single disease using easy-to-follow schematics and a focused approach to facilitate reader learning. Pursuing a comprehensive, the book covers not only common skin diseases such as psoriasis, lichen planus, eczema, erythrasma, cutaneous tuberculosis, leprosy, leishmaniasis and oral submucous fibrosis, but also rare tropical diseases such as sporotrichosis, mycetoma, rhinosporodiosis, lobomycosis, mucormycosis and subcutaneous zygomycosis. It also addresses aesthetic concerns by covering hypopigmented and hyperpigmented disorders in pigmented skin such as guttate hypomelanosis, vitiligo, progressive macular hypomelanosis, chemical or physical induced depigmentation, melasma, sebo-melanosis, lichen and macular amyloidosis. Offering comprehensive coverage of dermatological disorders and diseases in pigmented skin, the book is a must-have resource for dermatology trainees and practitioners who treat or care for pigmented skin patients.

Over the past few decades there have been major advances in computed tomography (CT) to improve the performance of cardiac imaging. Thanks to the improved scanning speed, power boost tubes, and increased-width detectors, the latest CT technology delivers greater coverage, better spatial and temporal resolution, and functional information on cardiac diseases. Focusing on cardiac CT imaging, this book offers case-based information on cardiac diseases, presents the current technical status, and highlights applications, helping readers systematically understand how cardiac CTs are performed and interpreted in clinical practice. Divided into six chapters, it broadly discusses the characteristics of CT imaging and its applications to coronary artery disease (CAD); non-atherosclerotic coronary artery disease; congenital heart disease; cardiac neoplasms; cardiomyopathy and aortic diseases.

This atlas presents the detailed anatomy of the external carotid arterial branches for interventional radiology.In the last decade, interventional neuroradiology (endovascular treatment via the cerebral arteries) has advanced rapidly thanks to the development of new technological devices, such as detachable coils for brain aneurysm. Anatomical knowledge of the target vessels is essential for interventional neuroradiology, and innovative new imaging techniques like 3D angiography and image fusion techniques can depict the detailed anatomy of small vessels together with surrounding organs. This compilation provides not only 2D angiography images, but also 3D and cross-sectional images, as well as fusion images mainly based on 3D angiography, CT and MRI to further readers¿ understanding of the complicated anatomy of the small branches of the external carotid artery. It also describes the branches¿ clinical significance in endovascular treatment.The book offers a valuable resource for interventional neuroradiologists, neurosurgeons and neurologists, as well as otolaryngologists, plastic surgeons, radiology technicians, and all medical staff involved in interventional radiology.

This book provides arthroscopy techniques and applications to clinical practitioners, including sports medicine therapeutics, orthopaedic surgeons, specialist training candidates, rehabilitation clinicians. It also includes small incisions per minimally invasive surgery using a camera mounted on a thin tube to visualize, repair and reconstruct joint-associated structures. Arthroscopy technique as a minimally invasive surgical method, in Orthopeadics is not only for the treatment of intra-articular diseases but also an advanced conception for treatment of extra-articular diseases and peri-articular fractures. After performing years of arthroscopy, authors intend to provide an elite technique demonstration of each procedure, including indications, technique, complications, and results.There are three main parts of the book, including the extra-articular application of arthroscopy techniques, arthroscopic minimally invasive techniques for the treatment of intra-articular fractures, and Innovative technology for repair and reconstruction of bone and joint injuries. Key technical points and experience of arthroscopic repair of joint injuries, dislocation of joints, fixation of the intra-articular fractures, ligament release for limbs are illustrated. Special situations such as congenital torticollis, deltoid contracture, gluteal muscle contracture, bone grafting, removal of locking plate and screw and benign tumors treatment are also included.

This book consists the basic theories and comprehensive skills of surgery, plastic surgery and chin surgery. The book contains more than 1900 color surgical photos, which mainly from lip and palate surgery in ¿Operation Smile¿ and the accumulation in decades of clinical practice. It briefly introduces various surgical methods of cleft lip and palate and alternative methods, procedures and steps of recommended repair surgeries by the way of pictures and graphic. It also emphasizes on describing common and practical cleft lip and palate surgery, and explores innovative surgical methods, operative techniques and key points. By means of schematic diagrams and surgical photos, various surgical procedures for cleft lip and palate are introduced. It is a useful reference book for surgeons in plastic surgery, oral surgery, cosmetic surgery and otolaryngology.

This Atlas provides many beautiful images obtained with state-of-the-art technologies, including optical coherence tomography (OCT), OCT angiography, fundus autofluorescence, and wide-field fundus imaging, as well as traditional images and fluorescein/ICG angiograms. Gathered at the world¿s largest High Myopia Clinic, the images are based on the long-term follow-up data of more than 6,000 patients from Japan and abroad. Recent advances in imaging technologies have yielded many new observations and allowed us to detect new lesions, e.g. myopic traction maculopathy (or macular retinoschisis) and dome-shaped macula. An especially interesting aspect: the images obtained by ¿3D MRI of the eye¿ and ¿ultra wide-field OCT¿ to visualize staphylomas. These techniques were established by the editor¿s group and make it possible to record the entire shapes of the eye, offering a scan width of up to 23 mm and scan depth of 5 mm. They have since been used to visualize posterior staphyloma,which was previously impossible to view because it spanned such a wide range of the eye. In addition, readers will learn what types of eye deformity occur in pathologic myopia and how they damage the macula/optic nerve. With this Atlas, readers will learn how to accurately diagnose each lesion of pathologic myopia, how eye deformity causes blinding complications, and how to identify patients with a poor prognosis. In short, it provides essential information that can¿t be found elsewhere.

This Atlas provides many beautiful images obtained with state-of-the-art technologies, including optical coherence tomography (OCT), OCT angiography, fundus autofluorescence, and wide-field fundus imaging, as well as traditional images and fluorescein/ICG angiograms. Gathered at the world¿s largest High Myopia Clinic, the images are based on the long-term follow-up data of more than 6,000 patients from Japan and abroad. Recent advances in imaging technologies have yielded many new observations and allowed us to detect new lesions, e.g. myopic traction maculopathy (or macular retinoschisis) and dome-shaped macula. An especially interesting aspect: the images obtained by ¿3D MRI of the eye¿ and ¿ultra wide-field OCT¿ to visualize staphylomas. These techniques were established by the editor¿s group and make it possible to record the entire shapes of the eye, offering a scan width of up to 23 mm and scan depth of 5 mm. They have since been used to visualize posterior staphyloma, which was previously impossible to view because it spanned such a wide range of the eye. In addition, readers will learn what types of eye deformity occur in pathologic myopia and how they damage the macula/optic nerve. With this Atlas, readers will learn how to accurately diagnose each lesion of pathologic myopia, how eye deformity causes blinding complications, and how to identify patients with a poor prognosis. In short, it provides essential information that can¿t be found elsewhere.

Infections in intensive care is a very broad topic, and this book provides concise yet comprehensive coverage. It focuses on the appropriate and judicious use of microbiological, radiological and point-of-care tests in diagnostic work-ups and evidence-based management protocols. Moreover, it offers essential information on the diagnosis and management of commonly encountered infections in the intensive care unit, making it a handy ready-reference manual for intensivists.

This book offers cutting-edge evidence on using rapid on-site evaluation (ROSE) for the diagnosis of neoplastic diseases in pulmonology. ROSE has become an efficient interventional diagnostics tool and important reference for lung disease differentiation, increasing the adequacy rate, diagnostic yield and accuracy of interventional pulmonary procedures. By performing a rapid stain in the bronchoscopy suite, with evaluation by a trained physician, ROSE can be used to ensure the collection of suitable and sufficient material for ancillary studies in an era of caner-targeted therapy.ROSE holds considerable value in terms of evaluating sampling adequacy for further immunohistochemistry testing, microbiology studies, flow cytometry analysis, and molecular assays, providing a preliminary diagnosis for patient care. The first part of the book discusses the key principles for performing ROSE procedures and reviews key anatomical structures in the lung. It also covers typical cellular characteristics on the ROSE scale for pulmonary solid malignancies.The second part of the book features abundant figures and illustrations of ROSE cytopathology in common neoplastic diseases, e.g. adenocarcinoma, squamous-cell carcinoma and small cell lung cancer, while also exploring more unusual types, e.g. pneumonia-type carcinoma of the lung (PTCL), mucinous adenocarcinoma, lung mixed carcinoma, pulmonary metastases from extrapulmonary primary tumors, large cell neuroendocrine carcinoma (LCNEC), and lymphoma. This book is part of the 4-volume collection ROSE in Diagnostic Interventional Pulmonology.

This book brings together information on all aspects of ossification of the posterior longitudinal ligament (OPLL), a hyperostotic condition of the spine that can cause severe neurological deficits. Since the second edition of this book was published in 2006, there have been tremendous advances in the field, and this third edition provides updated information on the disease¿s epidemiology, diagnosis and treatment, while also addressing ossification of the ligamentum flavum (OLF) and diffuse idiopathic spinal hyperostosis. As such, it offers a valuable resource for all those who want to gain a deeper understanding of OPLL/OLF and those involved in making decisions about its treatment.

This book covers some well-known and some unexplored pathological aspects of management of peritoneal metastases and should be read by both surgeons and pathologists involved in the management of peritoneal surface malignancies. The evaluation of cytoreductive surgery specimens is explored for the prognostic information it can provide and recommendations for evaluation of such specimens are provided. The pathways and patterns of peritoneal dissemination and their clinical implications on the extent of surgery performed and other aspects of management are discussed for some common peritoneal tumours. The exploratory studies presented here provide a new perspective on the surgical resection of peritoneal metastases. Other important aspects of pathological evaluation like pathological response to chemotherapy, diagnosis and classification of rare peritoneal tumors have also been covered in different chapters. Keeping in sync with the progress in molecular oncology, the role of molecular oncology in the current and future management of peritoneal metastases is addressed for different tumors.