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This handbook offers a comprehensive review on career guidance, with an emphasis on the applied aspects of guidance together with research methods and perspectives.

Particular emphasis has been given to specific aspects of the development process including lead generation and optimization, pharmacokinetics, ADME analysis, pharmacodynamics, toxicity and efficacy assessment, investigational new drug (IND) and new drug application (NDA) and the design of clinical trial and their phases.

The most damning criticism of markets is that they are morally corrupting. Even Adam Smith, who famously celebrated markets, believed that there were moral costs associated with life in market societies.

The second edition of the successful book "Your Guide to Pediatric Anesthesia" offers a practical approach to pediatric anesthesia with a concise account of the topic in a reader-friendly format.

At a time of hyper-partisanship, media fragmentation and "fake news", the work of investigative journalism has never been more important.

This book concentrates on the marine mammalian group of Odontocetes, the toothed whales, dolphins, and porpoises. The aim is to give a modern flavor of present knowledge of ethology and behavior of generally large-brained behaviorally flexible mammals that have evolved quite separately from social mammals on land.

This book explores different forms of mediated offence in the context of Trump's America, Brexit Britain, and the rise of far-right movements across the globe. In this political landscape, the so-called 'right to offend' is often seen as a legitimate weapon against a 'political correctness gone mad' that stifles 'free speech'.

Homeopathy is over 200 years old and is still experiencing an uninterrupted influx of new practitioners and patients. Many patients and therapists swear by this "alternative healing method", which in some countries is even financed by health insurances. This seems completely incomprehensible to critics: For them it is clearly evident that homeopathy is hopelessly unscientific and has at best a placebo effect. The positions of supporters and opponents seem to be just as immutable as they are incompatible. This book answers some essential and fascinating questions: What remains of the founding ideas of homeopathy in 21st century medicine? Does it really work and, if so, how? Which of the original theories can we still apply today with a clear conscience and use for the benefit of patients and the healthcare system? Where does homeopathy have its limits and does it indeed need to be critically reconsidered and evaluated? The author has dealt with the points of criticism for years, but at the same time also takes seriously the wishes and concerns of patients who often feel insufficiently cared for by conventional medical practice. Against the background of her own personal history, her book attempts to bridge the gap between these two traditionally opposing camps.

This book is a continuation of our recently published book "Algebraic formalization of smart systems. Maltsev's theory of algebraic systems and the theory of fractals developed by Benoit Mandelbrot, to investigate smart systems in more detail.

In this book, the authors, as policy analysts, examine the overall context and dynamics of modern medicine, focusing on the changing conditions of medical practice through the lens of corporatization of medicine, physician unionization, physician strikes, and current health policy directions. Conditions affecting the American medical profession have been dramatically altered by the continuing crises of cost increases, quality concerns, and lack of access facing our population, along with the ongoing corporatization toward bottom-line dictates. Pressures on practitioners have been intensifying with much greater scrutiny over their clinical decision-making. Topics explored among the chapters include:History of the Corporatization of American Medicine: The Market Paradigm ReignsPharmaceuticals, Hospitals, Nursing Homes, Drug Store Chains, and Pharmacy Benefit Manager/Insurer IntegrationMedical Practice: From CottageIndustry to Corporate PracticeMedical Malpractice Crisis: Oversight of the Practice of MedicineBig Data: Information Technology as Control over the Profession of MedicinePhysician Employment Status: Collective Bargaining and StrikesThe Corporatization of American Health Care offers different perspectives with the hopes that physicians will unite in a new awareness and common cause to curtail excessive profit-making, renew professional altruism, restore the charitable impulse to health provider institutions, and unite with other professionals to truly raise levels of population health and the quality of health care. It is also a necessary resource for health policy analysts, healthcare administrators, health law attorneys, and other associated health professions.

Every global crisis highlights the strategic importance of industrial and non-profit supply chains for society. In terms of coping with unforeseen and unpredictable events, supply chain resilience enables the parties and networks involved to stay successful during and after the disruption. Furthermore, a resilient supply chain contributes to the sustainable competitive advantage of the entire value chain.Written by scholars and practitioners alike, this book not only puts forward a new framework for resilience in supply chain management, but also presents best practice cases from various areas and industries. As a particular highlight, it includes a Delphi study that gathers state-of-the-art insights from supply chain leaders.In addition to practical approaches, methods and tools, the book also offers food for thought on the future of supply chain resilience. As such, it offers a valuable resource for current and future managers in the public and private sector, as well as researchers and students engaged in this field.

This fully revised and expanded 2nd edition provides a single authoritative resource describing the concepts of color and the application of color science across research and industry. Significant changes for the 2nd edition include: New and expanded sections on color engineeringMore entries on fundamental concepts of color science and color termsMany additional entries on specific materialsFurther material on optical concepts and human visual perceptionAdditional articles on organisations, tools and systems relevant to colorA new set of entries on 3D presentation of color In addition, many of the existing entries have been revised and updated to ensure that the content of the encyclopedia is current and represents the state of the art. The work covers the full gamut of color: the fundamentals of color science; the physics and chemistry; color as it relates to optical phenomena and the human visual system; and colorants and materials. The measurement of color is described through entries on colorimetry, color spaces, color difference metrics, color appearance models, color order systems and cognitive color. The encyclopedia also has extensive coverage of applications throughout industry, including color imaging, color capture, display and printing, and descriptions of color encodings, color management, processing color and applications relating to color synthesis for computer graphics are included. The broad scope of the work is illustrated through entries on color in art conservation, color and architecture, color and education, color and culture, and biographies of some of the key figures involved in color research throughout history. With over 250 entries from color science researchers across academia and industry, this expanded 2nd edition of the Encyclopedia of Color Science and Technology remains the most important single resource in color science.

This eighth volume of Imagine Math is different from all the previous ones. The reason is very clear: in the last two years, the world changed, and we still do not know what the world of tomorrow will look like. Difficult to make predictions. This volume has a subtitle Dreaming Venice. Venice, the dream city of dreams, that miraculous image of a city on water that resisted for hundreds of years, has become in the last two years truly unreachable. Many things tie this book to the previous ones. Once again, this volume also starts like Imagine Math 7, with a homage to the Italian artist Mimmo Paladino who created exclusively for the Imagine Math 8 volume a new series of ten original and unique works of art dedicated to Piero della Francesca. Many artists, art historians, designers and musicians are involved in the new book, including Linda D. Henderson and Marco Pierini, Claudio Ambrosini and Davide Amodio. Space also for comics and mathematics in a Disney key. Many applications, from Origami to mathematical models for world hunger. Particular attention to classical and modern architecture, with Tullia Iori.As usual, the topics are treated in a way that is rigorous but captivating, detailed and full of evocations. This is an all-embracing look at the world of mathematics and culture.

This open access textbook introduces the emerging field of Development Engineering and its constituent theories, methods, and applications. It is both a teaching text for students and a resource for researchers and practitioners engaged in the design and scaling of technologies for low-resource communities. The scope is broad, ranging from the development of mobile applications for low-literacy users to hardware and software solutions for providing electricity and water in remote settings. It is also highly interdisciplinary, drawing on methods and theory from the social sciences as well as engineering and the natural sciences.The opening section reviews the history of ¿technology-for-development¿ research, and presents a framework that formalizes this body of work and begins its transformation into an academic discipline. It identifies common challenges in development and explains the book¿s iterative approach of ¿innovation, implementation, evaluation, adaptation.¿ Each of the next six thematic sections focuses on a different sector: energy and environment; market performance; education and labor; water, sanitation and health; digital governance; and connectivity. These thematic sections contain case studies from landmark research that directly integrates engineering innovation with technically rigorous methods from the social sciences. Each case study describes the design, evaluation, and/or scaling of a technology in the field and follows a single form, with common elements and discussion questions, to create continuity and pedagogical consistency. Together, they highlight successful solutions to development challenges, while also analyzing the rarely discussed failures. The book concludes by reiterating the core principles of development engineering illustrated in the case studies, highlighting common challenges that engineers and scientists will face in designing technology interventions that sustainably accelerate economic development.Development Engineering provides, for the first time, a coherent intellectual framework for attacking the challenges of poverty and global climate change through the design of better technologies. It offers the rigorous discipline needed to channel the energy of a new generation of scientists and engineers toward advancing social justice and improved living conditions in low-resource communities around the world.