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Este manual ofrece orientaciones prácticas para la contratación y gestión del transporte internacional de mercancías por carretera desde el punto de vista de la intermodalidad y la comodalidad.Alfonso Cabrera, profesor de Comercio Exterior y de Transporte Internacional y experto en la optimización de los procesos de transporte, analiza la oferta de servicios del sector, describe los diversos tipos de infraestructuras de la que pueden disponer los operadores del transporte y sus clientes y presenta los aspectos fundamentales que rigen su actividad (aplicación del convenio CMR, reglas Incoterms® 2010, optimización de la cadena de transportes, entre otros), aportando casos prácticos que facilitan la adquisición de conocimientos.La suma de competencias y de recursos convierten esta obra en una herramienta imprescindible para los cargadores que contratan los servicios de transporte internacional de mercancías y para los transportistas que los realizan.

El objetivo de esta obra es facilitar la comprensión de los elementos que intervienen en la cadena de suministro de las empresas. Para ello, se ofrecen una serie de herramientas que ayudan a directivos y técnicos a desarrollar la mejora continua y la planificación estratégica de la cadena de suministro y la de la propia empresa.Los autores exponen las características diferenciales de los sectores económicos desde la óptica de la gestión de existencias, la comprensión y utilización de los métodos cuantitativos de modelaje, como series temporales y modelos lineales de regresión, el cálculo del stock de seguridad o la planificación de producción agregada, entre otros temas de interés.Este libro pone de relevancia la necesidad del soporte teórico y destaca la importancia de la utilización de los sistemas informáticos de gestión.Se ilustra con casos reales que favorecen la total comprensión de las cuestiones expuestas.

La esclerosis múltiple es una enfermedad con gran impacto social y sanitario en España.Gracias al esfuerzo de los profesionales y pacientes, se ha conseguido mejorar su conocimiento y atención, lo que ha redundado en una mejoría de la calidad de vida de las personas que la padecen.Sin embargo, es necesario continuar con esta labor de difusión y conocimiento para alcanzar una adecuada integración de los enfermos y de sus familias en la sociedad.Este libro tiene un objetivo doble. Por un lado, divulgar los aspectos básicos de la investigación que se realiza sobre la esclerosis múltiple, para que alcance al público más amplio de personas interesadas en esta enfermedad, siendo éste también uno de los fines prioritarios de la Red Española de Esclerosis Múltiple.Por otro, ofrecer una monografía actualizada que resuma los principales aspectos de la clínica diagnóstica y del tratamiento de esta patología, que sea de utilidad para los profesionales que trabajan en su detección y control, para los pacientes afectos y para las personas interesadas en la misma.Para ello, hemos contado con un panel de excelentes investigadores y neurólogos de la Red y colaboradores, gracias a cuyo esfuerzo ofrecemos, en capítulos breves y de fácil lectura, un resumen del conocimiento actual sobre la esclerosis múltiple.

Esta monografía es de gran utilidad a hepatólogos y gastroenterólogos, a residentes y, en general, a quienes se interesan por conocer mejor el virus dela hepatitis C. Desde el descubrimiento del virus VHC, a pesar de los avances en el conocimiento de su biología, la infección crónica por VHC todavía constituye un problema importante de salud pública que afecta a alrededor del 3 % de la población mundial. A menudo, esta infección es asintomática y, por tanto, muchas personas infectadas ignoran su situación. En Europa, más del 90 % de las personas infectadas por el VHC no han sido aún diagnosticadas.

El cáncer de colon y recto, sumando ambos sexos, representa el tumor de máxima incidencia en España actualmente. Tan alta prevalencia expone a la medicina primaria a la complejidad del diagnóstico, así como a las complicaciones genera-das por el tratamiento del cáncer.Ante esta realidad, la presente obra aspira a llenar un hueco generado por la literatura especializada, excelente por otro lado, ofreciendo al médico de atención primaria los aspectos básicos de concepto, riesgo hereditario, signos de alarma y estrategias generales de tratamiento. Todo ello sin la necesidad de profundizar en porcentajes y pautas de quimioterapia (presentes en forma de tablas para quien desee conocerlas) de poco interés para un médico no dedicado al tratamiento del cáncer. El lector también encontrará descritos los efectos secundarios de la quimioterapia, así como su tratamiento, un problema que resulta de gran interés por ser altamente fre-cuente en la consulta ambulatoria.Esta obra está dirigida por el prestigioso doctor Albert Abad Esteve, del Servicio de Oncología Médica del Hospital Uni-versitari Germans Trias i Pujol (Institut Català d'Oncologia), con la colaboración de eminentes especialistas que, en esta ocasión, se dirigen de manera clara y sencilla a sus colegas no oncólogos para ofrecerles una revisión de los aspectos más importantes de esta neoplasia.

La movilidad de las personas y el movimiento de las mercancías configuran el marco de la logística urbana. Un reto para todos los grandes núcleos urbanos que afecta a la actividad de las empresas y las organizaciones privadas, a las actuaciones de la Administración y a la calidad de vida de los ciudadanos. La logística urbana es el eslabón de la cadena de transporte de mercancías que actúa dentro de las poblaciones con el objetivo de dar un servicio de abastecimiento y distribución, tanto a los comercios como al consumidor final. Este libro expone las cuestiones más relevantes en torno a la logística urbana, presenta los casos más significativos de muchas ciudades del mundo, describe las soluciones adoptadas y, a su vez, propone alternativas sostenibles de desarrollo para la distribución urbana de mercancías, en una lógica de proporción entre el uso de suelo, el crecimiento urbano y demográfico y la creación de riqueza y redes de servicios.

Este manual ofrece una amplia visión de las posibilidades de cobertura de los seguros frente a los riesgos de las mercancías en el transporte por vía marítima, terrestre y aérea.A través de numerosos ejemplos prácticos y sentencias, esta obra aborda todos los conceptos clave de los seguros relacionados con el transporte de mercancías, desde el propio concepto de riesgo y la contratación del seguro, los tipos de póliza, los siniestros y las averías, hasta el desarrollo del sobreseguro, el abandono, las indemnizaciones y las reclamaciones que pueden suscitarse.Los autores, experimentados profesionales del derecho, desde un punto de vista práctico y didáctico, ofrecen una herramienta de gestión para un amplio abanico de profesionales, especialmente útil para quienes operan en el comercio internacional, tanto si deben contratar un seguro por ser propietarios de las mercancías que se transportan, como para los operadores del transporte o los que desean formarse en materia de seguros.

La presente obra ofrece una profunda revisión de los principales problemas patogénicos, epidemiológicos, clínicos, terapéuticos y de prevención de la infección provocada por Staphylococcus aureus. Su finalidad es que sirva de suplemento educacional, aportando a los profesionales de la sanidad una herramienta útil para desempeñar su trabajo diario.

El objetivo de este libro es presentar y revisar las técnicas más novedosas y las últimas terapias en el tratamiento de diversas enfermedades gastrointestinales.La complejidad fisiopatológica y genética, el aumento de su aparición a edades cada vez más tempranas y la ausencia de tratamientos curativos definitivos convierten a la enfermedad inflamatoria intestinal en una de las patologías del mundo de la Gastroenterología que mayor interés ha despertado en los últimos años. En esta obra se presentan los factores patogénicos responsables de la enfermedad de Crohn y de la colitis ulcerosa así como las nuevas terapias inmunomoduladoras y biológicas desarrolladas gracias al descubrimiento de aspectos genéticos y fisipatológicos fundamentales en la enfermedad inflamatoria intestinal.Los especialistas del aparato digestivo, los residentes e internistas en esta especialidad y en otras afines, hallarán en sus páginas las claves del que podría ser el principio de una nueva era en el tratamiento de los pacientes.

Esta obra está dedicada al virus de la hepatitis B, patología que unos años atrás parecía en franca regresión a causa de la vacunación masiva implantada en las escuelas. Actualmente, se constata un recrudecimiento de la misma. Para exponer de manera clara y concisa los conocimientos sobre la hepatitis B, se ha contado con la colaboración de un equipo de hepatólogos y microbiólogos con amplia experiencia en hospitales españoles, con la finalidad de que sirva de elemento de consulta para médicos en general y residentes, gracias a sus aspectos eminentemente prácticos y clínicos.

Las enfermedades inflamatorias intestinales han incrementado su incidencia y, aunque la introducción de fármacos inmunosupresores y biológicos supone un avance en su tratamiento, genera dudas sobre su posible asociación con el desarrollo de infecciones.Esta obra se presenta en tres grandes bloques, aportando siempre datos actualizados. El primero aborda aspectos relacionados con las infecciones prevenibles por vacunas y las recomendaciones específicas en pacientes con enfermedad inflamatoria intestinal, así como la respuesta inmune de algunos pacientes. El segundo, se centra en la tuberculosis, por la importancia de las medidas de prevención y profilaxis de la tuberculosis latente en pacientes bajo tratamiento con fármacos biológicos. Y, por último, el tercero trata de la gripe A y de sus consecuencias en pacientes con enfermedad inflamatoria, una pregunta constante en las consultas médicas.

K.C. Hall is back. So back!>Kalindra Muze has it out for our beloved starlet.The success of Shadows of the Moon 2 hangs in the balance.>Meanwhile in Rapid City, Scott is up to...something. Sophie, too.Also, Luisa has a proposal that K.C. can't not turn down. Except, she does. At first.Then we go to Canada. For a show about a library....where silence....is deadly.

K.C. (not her birth name) had a crappy childhood.Her father died in a convenience store robbery a few years ago.Now she's about to become a big time movie star.Fingers crossed.But first, she'll have to deal with her estranged mother who just wrote a book.Join her as she avoids the paparazzi, makes peace with her past, makes some new friends and maybe, just maybe gets the big break she needs.

A straight-A student, Emma Snow seems like a happy, normal child-and she would be, were it not for the continuous horrors she experiences at home. Emma Snow seems like an ordinary child. Perhaps a little quiet, with a hearing impairment...she's a straight-A student who loves to read. Emma lives with her two sisters, her father, and her stepmother in a house on Third Street. A house the neighbors avoid discussing. Within the walls of the Snow residence, Emma and her sisters are the target of a never-ending stream of military-style beatings and sexual assault. For ten years, Emma and her sisters suffer-with one short, blissful stay in a foster home showing them what life could be like. Emma lives on constant high alert, always waiting for her father's next explosion. All she wants is to live the life other little girls take for granted: To laugh. To be safe. To be a kid. When a crisis center counselor intervenes, it seems Emma and her sisters will finally be free of their tormenter. Surely the judge won't let Emma's abuser go free? But things don't always play out as they should, even when a child predator confesses his crimes.

Tāne is the Maori god of the forest and his Patu is his weapon, his power. Nature's cycle is broken, as you may have noticed, and the carbon in the air has a very limited pathway back to the ground, causing climate change.

When Mrs Salamo, the headmistress, calls Wendi and Kip Kip into her office to meet distinguished historian, Professor Tubulukawa, they are naturally suspicious. After their previous adventures, they simply don't want to enter his odd-looking time machine.However, when he promises it will help Papua New Guinea, they decide to assist the professor perfect the eccentric contraption. As they step into the rickety machine, they are whisked across time, first dropping in on an aristocratic English family in World War II, then back to Papua New Guinea to witness the same war in the jungles of Bougainville. Kip Kip and Wendi then pick up some very interesting time-travelling passengers.Finally, they see their country move from colony under foreign rule to an independent state, where they help local people stop the destruction of vast rain forests. This is Wendi and Kip Kip's second adventure, this time taking them through important events that shaped modern day Papua New Guinea.

Theological reflections on the moral life in general and current issues in particular.

A Noble Queen: A Romance of Indian History by Philip Meadows Taylor is a novel written in three volumes that depicts one of the most important epochs in the history of the Deccan. The book features the life of the noble queen Chand Bibi who is remembered not only as the preserver of Bijapur, but for the heroic opposition she maintained against the Mughal armies in their first invasion of the Deccan and siege of Ahmednagar. Following an alliance policy, Chand Bibi was married to Ali Adil Shah I of the Bijapur Sultanate, who favored Shi'as. After his death in 1580, the Shi'a nobles proclaimed his nine-year-old nephew Ibrahim Adil Shah II as the ruler. A Deccani general called Kamal Khan seized power and became the regent. Kamal Khan was disrespectful towards Chand Bibi, who felt that he had ambitions to usurp the throne. Chand Bibi plotted an attack against Kamal Khan. Kamal Khan was captured while fleeing and was beheaded in the fort. Kishvar Khan became the second regent of Ibrahim. In a battle against the Ahmednagar Sultanate at Dharaseo, the Bijapur army led by him captured all the artillery and elephants of the enemy army. After the victory, Kishvar Khan ordered other Bijapuri generals to surrender all the captured elephants to him. The elephants were highly valued, and the other generals took great offense. Along with Chand Bibi, they hatched a plan to eliminate Kishvar Khan. Chand Bibi challenged Kishvar Khan, but he got her imprisoned and tried to declare himself the king. However, Kishvar Khan became very unpopular among the rest of the generals. He was forced to flee when a joint army led by a Habshi general called Ikhlas Khan marched to Bijapur. Following this, Chand Bibi acted as the regent for a short time. Ikhlas Khan then became the regent and was soon challenged by the other Habshi generals. Taking advantage of the situation in Bijapur, Ahmednagar's Nizam Shahi sultan planned to attack Bijapur. The troops available at Bijapur were not sufficient to repulse this attack. The Habshi generals realized that they could not defend the city alone, and tended their resignation to Chand Bibi. When order was restored in Bijapur kingdom, Chand Bibi returned to Ahmednagar. In 1591, the Mughal emperor Akbar asked all the four Deccan sultanates to acknowledge his supremacy. All the sultanates evaded compliance, and Akbar's ambassadors returned in 1593. In 1595, Ibrahim Nizam Shah, the ruler of Ahmednagar Sultanate was killed in a fierce battle. After his death, some nobles felt that his infant son Bahadur Shah should be proclaimed the king under the regency of Chand Bibi (his father's aunt). However, the Deccani minister Miyan Manju proclaimed the twelve-year-old Ahmad Nizam Shah II as the ruler. The Habshi nobles of Ahmednagar, led by Ikhlas Khan, were against this plan. The rising dissent among the nobles prompted Miyan Manju to invite Akbar's son Murad Mirza to march his army to Ahmednagar. While Murad was on the way to Ahmednagar, many noblemen left Ikhlas Khan and joined Miyan Manju. Miyan Manju defeated Ikhlas Khan and other opponents. Now, he regretted having invited the Mughals, but it was too late. He requested Chand Bibi to accept the regency and marched out of Ahmednagar. Chand Bibi accepted the regency and proclaimed Bahadur Shah king of Ahmednagar.

A Noble Queen: A Romance of Indian History by Philip Meadows Taylor is a novel written in three volumes that depicts one of the most important epochs in the history of the Deccan. The book features the life of the noble queen Chand Bibi who is remembered not only as the preserver of Bijapur, but for the heroic opposition she maintained against the Mughal armies in their first invasion of the Deccan and siege of Ahmednagar. Following an alliance policy, Chand Bibi was married to Ali Adil Shah I of the Bijapur Sultanate, who favored Shi'as. After his death in 1580, the Shi'a nobles proclaimed his nine-year-old nephew Ibrahim Adil Shah II as the ruler. A Deccani general called Kamal Khan seized power and became the regent. Kamal Khan was disrespectful towards Chand Bibi, who felt that he had ambitions to usurp the throne. Chand Bibi plotted an attack against Kamal Khan. Kamal Khan was captured while fleeing and was beheaded in the fort. Kishvar Khan became the second regent of Ibrahim. In a battle against the Ahmednagar Sultanate at Dharaseo, the Bijapur army led by him captured all the artillery and elephants of the enemy army. After the victory, Kishvar Khan ordered other Bijapuri generals to surrender all the captured elephants to him. The elephants were highly valued, and the other generals took great offense. Along with Chand Bibi, they hatched a plan to eliminate Kishvar Khan. Chand Bibi challenged Kishvar Khan, but he got her imprisoned and tried to declare himself the king. However, Kishvar Khan became very unpopular among the rest of the generals. He was forced to flee when a joint army led by a Habshi general called Ikhlas Khan marched to Bijapur. Following this, Chand Bibi acted as the regent for a short time. Ikhlas Khan then became the regent and was soon challenged by the other Habshi generals. Taking advantage of the situation in Bijapur, Ahmednagar's Nizam Shahi sultan planned to attack Bijapur. The troops available at Bijapur were not sufficient to repulse this attack. The Habshi generals realized that they could not defend the city alone, and tended their resignation to Chand Bibi. When order was restored in Bijapur kingdom, Chand Bibi returned to Ahmednagar. In 1591, the Mughal emperor Akbar asked all the four Deccan sultanates to acknowledge his supremacy. All the sultanates evaded compliance, and Akbar's ambassadors returned in 1593. In 1595, Ibrahim Nizam Shah, the ruler of Ahmednagar Sultanate was killed in a fierce battle. After his death, some nobles felt that his infant son Bahadur Shah should be proclaimed the king under the regency of Chand Bibi (his father's aunt). However, the Deccani minister Miyan Manju proclaimed the twelve-year-old Ahmad Nizam Shah II as the ruler. The Habshi nobles of Ahmednagar, led by Ikhlas Khan, were against this plan. The rising dissent among the nobles prompted Miyan Manju to invite Akbar's son Murad Mirza to march his army to Ahmednagar. While Murad was on the way to Ahmednagar, many noblemen left Ikhlas Khan and joined Miyan Manju. Miyan Manju defeated Ikhlas Khan and other opponents. Now, he regretted having invited the Mughals, but it was too late. He requested Chand Bibi to accept the regency and marched out of Ahmednagar. Chand Bibi accepted the regency and proclaimed Bahadur Shah king of Ahmednagar.

"All happy families are alike; each unhappy family is unhappy in its own way." ― Leo Tolstoy, Anna Karenina Anna Karenina (1878) by Leo Tolstoy deals with subjects of family, betrayal, faith, marriage, desire, Imperial Russian society, and rural vs. city life. Anna, the protagonist, is married to a distinguished official in St. Petersburg and moves in the highest circles of Russian Society with the reputation of a charming woman. Anna's life, however, takes an interesting turn when she encounters a dashing cavalry officer Count Alexei Kirillovich Vronsky at a party and an extramarital affair begins between the two. The affair scandalizes the social circles of St. Petersburg and forces the young lovers to flee for Italy in a search for happiness. Their lives further unravel as they return to Russia and the complexities in their lives and the lives of people around them increases.

A Noble Queen: A Romance of Indian History by Philip Meadows Taylor is a novel written in three volumes that depicts one of the most important epochs in the history of the Deccan. The book features the life of the noble queen Chand Bibi who is remembered not only as the preserver of Bijapur, but for the heroic opposition she maintained against the Mughal armies in their first invasion of the Deccan and siege of Ahmednagar. Following an alliance policy, Chand Bibi was married to Ali Adil Shah I of the Bijapur Sultanate, who favored Shi'as. After his death in 1580, the Shi'a nobles proclaimed his nine-year-old nephew Ibrahim Adil Shah II as the ruler. A Deccani general called Kamal Khan seized power and became the regent. Kamal Khan was disrespectful towards Chand Bibi, who felt that he had ambitions to usurp the throne. Chand Bibi plotted an attack against Kamal Khan. Kamal Khan was captured while fleeing and was beheaded in the fort. Kishvar Khan became the second regent of Ibrahim. In a battle against the Ahmednagar Sultanate at Dharaseo, the Bijapur army led by him captured all the artillery and elephants of the enemy army. After the victory, Kishvar Khan ordered other Bijapuri generals to surrender all the captured elephants to him. The elephants were highly valued, and the other generals took great offense. Along with Chand Bibi, they hatched a plan to eliminate Kishvar Khan. Chand Bibi challenged Kishvar Khan, but he got her imprisoned and tried to declare himself the king. However, Kishvar Khan became very unpopular among the rest of the generals. He was forced to flee when a joint army led by a Habshi general called Ikhlas Khan marched to Bijapur. Following this, Chand Bibi acted as the regent for a short time. Ikhlas Khan then became the regent and was soon challenged by the other Habshi generals. Taking advantage of the situation in Bijapur, Ahmednagar's Nizam Shahi sultan planned to attack Bijapur. The troops available at Bijapur were not sufficient to repulse this attack. The Habshi generals realized that they could not defend the city alone, and tended their resignation to Chand Bibi. When order was restored in Bijapur kingdom, Chand Bibi returned to Ahmednagar. In 1591, the Mughal emperor Akbar asked all the four Deccan sultanates to acknowledge his supremacy. All the sultanates evaded compliance, and Akbar's ambassadors returned in 1593. In 1595, Ibrahim Nizam Shah, the ruler of Ahmednagar Sultanate was killed in a fierce battle. After his death, some nobles felt that his infant son Bahadur Shah should be proclaimed the king under the regency of Chand Bibi (his father's aunt). However, the Deccani minister Miyan Manju proclaimed the twelve-year-old Ahmad Nizam Shah II as the ruler. The Habshi nobles of Ahmednagar, led by Ikhlas Khan, were against this plan. The rising dissent among the nobles prompted Miyan Manju to invite Akbar's son Murad Mirza to march his army to Ahmednagar. While Murad was on the way to Ahmednagar, many noblemen left Ikhlas Khan and joined Miyan Manju. Miyan Manju defeated Ikhlas Khan and other opponents. Now, he regretted having invited the Mughals, but it was too late. He requested Chand Bibi to accept the regency and marched out of Ahmednagar. Chand Bibi accepted the regency and proclaimed Bahadur Shah king of Ahmednagar.

The Footnail Series is an exciting, action packed historical based story set in fantasy fiction that follows a female hero who joins a battle between good and evil.

Killing Two Birds with One Rock.Val's always been unlucky at love - and a whole bunch of other things.But she's never actually felt cursed. Until now.When Tom gives Val an engagement ring for her fiftieth birthday, she wants to fly the coop. But it's Tom who skips out on the romantic getaway he planned. When he can't make the trip, one of Val's pals goes instead. On the first day, her friend entangles Val in a prank that ticks off the wrong tourist. On the second day, she gets Val charged with murder.(Did I mention Val was unlucky?)To clear her name, Val must go fishing to lure in the real culprit. But what kind of bait do you use when you don't want to get caught yourself?With both marriage and jail feeling like impending life sentences, Val's going to have to do some pretty fancy angling to get herself off the hook this time....If you like deeply flawed characters and laugh-out-loud situations, you'll love Five Oh. It's the fifth book in Lashley's hilarious Val Fremden Midlife Mystery series. She's a lovable, bungling mess who's a bit older, a tad more jaded, and a ton more experienced in big-time failure. Life's been tough for Val. Still, she always manages to find her way with sardonic humor and an intrepid spirit. A gin and tonic now and then helps, too.P.S. If you love humorous, page-turning mysteries like those by Deborah Brown, Julie Mulhern, Lucy Quinn, Tricia O'Malley, Gemma Halliday, Karen Cantwell, Tara Sivec, Liliana Hart, Libby Howard, Chelsea Field, Jana Deleon, Gina LaManna, Janet Evanovich, Denise Grover Swank, Amy Vansant, and Stephanie Bond, you just might love Glad One, too! What Readers are Saying about Five Oh: "Oh, Val! What a fiftieth birthday party! Another great entertaining read from Margaret Lashley!""A funny, thought-provoking book. I somehow find myself in the place of Val every time. I've cried and laughed and just related to all of her crazy life. It's so wonderful to read stories whose main character is 50ish!""Lashley's writing style is brilliant and hilarious. The plot is imaginatively twisty, the situations are wacky, the characters are lovable, and there is a surprise ending that I never saw coming. I wish the author could write as fast as I can read!""It is so refreshing to read a story with an original plot which does not rely on current blockbusters for ideas. This novel keeps you guessing and invested from start to end.""Val and pals enjoy another zany adventure. Find time to escape from your life to Val's!""Smartly written, funny and very engaging characters.""Val is a hoot, a mature woman starting over, reinventing herself, and figuring out who she is and wants to be when she grows up. (She's) her own superhero and I recommend reading this whole series."