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  •  
    685

    Nowadays, one of the main objectives of the fruit and vegetable industry is to develop innovative novel products with high quality, safety, and optimal nutritional characteristics in order to respond, with efficiency, to increasing consumer expectations. Various unconventional technologies (e.g., pulsed electric field, pulsed light, ultrasound, high pressure, and microwave drying) have emerged and enable the processing of fruits and vegetables in a way that increases their stability while preserving their thermolabile nutrients, flavour, texture, and overall quality. Some of these technologies can also be used for waste and byproduct valorisation. The application of fast noninvasive methods for process control is of great importance for the fruit and vegetable industry. The following Special Issue “Safety, Quality, and Processing of Fruits and Vegetables” consists of 11 papers which represent a high-value contribution to the existing knowledge on safety aspects, quality evaluation, and emerging processing technologies for fruits and vegetables.

  •  
    879

    Adequate quality of life and well-being of modern societies is only achievable with sustainable manufacturing processes that efficiently use raw materials, eliminate waste, and avoid the use of hazardous materials. All this is hardly conceivable without catalysis. In a world concerned with the exploitation of natural resources, catalysis can offer direct synthesis routes that maximize resource efficiency. The Iberoamerican society is far too significant and far too involved in global development, owing to its natural richness of resources, not to have an essential role in current developments and future directions. Catalysis, in the Iberoamerican academic and industrial communities, is recognized as a relevant scientific discipline that supports several strategic industrial sectors through the manufacturing of products and materials, and the operationalization of processes to produce energy and other utilities. As a reflection of this, once every two years the Iberoamerican Congress on Catalysis takes place to share and discuss the state-of-the-art of this discipline with the Federation of Iberoamerican Catalysis Societies. This book collected sixteen outstanding contributions, stemming from this exceptional event-one which will undoubtedly mark a turning point and could be a source of inspiration to all those involved in catalysis, particularly the young generation of competent researchers taking their first steps in this incredibly complex and beautiful discipline.

  •  
    685

    During the last few years, industrial fermentation technologies have advanced in order to improve the quality of the final product. Some examples of those modern technologies are the biotechnology developments of microbial materials, such as Saccharomyces and non-Saccharomyces yeasts or lactic bacteria from different genera. Other technologies are related to the use of additives and adjuvants, such as nutrients, enzymes, fining agents, or preservatives and their management, which directly influence the quality and reduce the risks in final fermentation products. Other technologies are based on the management of thermal treatments, filtrations, pressure applications, ultrasounds, UV, and so on, which have also led to improvements in fermentation quality in recent years. The aim of the issue is to study new technologies able to improve the quality parameters of fermentation products, such as aroma, color, turbidity, acidity, or any other parameters related to improving sensory perception by the consumers. Food safety parameters are also included.

  •  
    595

    Nowadays, one of the main objectives of the fruit and vegetable industry is to develop innovative novel products with high quality, safety, and optimal nutritional characteristics in order to respond, with efficiency, to increasing consumer expectations. Various unconventional technologies (e.g., pulsed electric field, pulsed light, ultrasound, high pressure, and microwave drying) have emerged and enable the processing of fruits and vegetables in a way that increases their stability while preserving their thermolabile nutrients, flavour, texture, and overall quality. Some of these technologies can also be used for waste and byproduct valorisation. The application of fast noninvasive methods for process control is of great importance for the fruit and vegetable industry. The following Special Issue "Safety, Quality, and Processing of Fruits and Vegetables" consists of 11 papers which represent a high-value contribution to the existing knowledge on safety aspects, quality evaluation, and emerging processing technologies for fruits and vegetables.

  •  
    595

    Artificial intelligence is deeply involved in our daily lives via reinforcing the digital transformation of modern economies and infrastructure. It relies on powerful computing clusters, which face bottlenecks of power consumption for both data transmission and intensive computing. Meanwhile, optics (especially optical communications, which underpin today''s telecommunications) is penetrating short-reach connections down to the chip level, thus meeting with AI technology and creating numerous opportunities. This book is about the marriage of optics and AI and how each part can benefit from the other. Optics facilitates on-chip neural networks based on fast optical computing and energy-efficient interconnects and communications. On the other hand, AI enables efficient tools to address the challenges of today''s optical communication networks, which behave in an increasingly complex manner. The book collects contributions from pioneering researchers from both academy and industry to discuss the challenges and solutions in each of the respective fields.

  •  
    779

    Geographic information systems (GISs) have played a vital role in Earth sciences by providing a powerful means of observing the world and various tools for solving complex problems. The scientific community has used GISs to reveal fascinating details about the Earth and other planets. This book on recent advances in GIS for Earth sciences includes 12 publications from esteemed research groups worldwide. The research and review papers in this book belong to the following broad categories: Earth science informatics (geoinformatics), mining, hydrology, natural hazards, and society.

  •  
    499

    This Special Issue is related to studies of the hydrogen production from formic acid decomposition. It is based on five research papers and two reviews. The reviews discuss the liquid phase formic acid decomposition over bimetallic (PdAg), molecular (Ru, Ir, Fe, Co), and heterogenized molecular catalysts. The gas-phase reaction is studied over highly dispersed Pd, Pt, Au, Cu, and Ni supported catalysts. It is shown that the nature of the catalyst''s support plays an important role for the reaction. Thus, N-doping of the carbon support provides a significant promotional effect. One of the reasons for the high activity of the N-doped catalysts is the formation of single-atom active sites stabilized by pyridinic N species present in the support. It is demonstrated that carbon materials can be N-doped in different ways. It can be performed either directly from N-containing compounds during the carbon synthesis or by a post-synthetic deposition of N-containing compounds on the carbon support with known properties. The Issue could be useful for specialists in catalysis and nanomaterials as well as for graduate students studying chemistry and chemical engineering. The reported results can be applied for development of catalysts for the hydrogen production from different liquid organic hydrogen carriers.

  •  
    595

    The rising trend in the global energy demand poses new challenges to humankind. The energy and mechanical engineering sectors are called to develop new and more environmentally friendly solutions to harvest residual energy from primary production processes. The Organic Rankine Cycle (ORC) is an emerging energy system for power production and waste heat recovery. In the near future, this technology can play an increasing role within the energy generation sectors and can help achieve the carbon footprint reduction targets of many industrial processes and human activities. This Special Issue focuses on selected research and application cases of ORC-based waste heat recovery solutions. Topics included in this publication cover the following aspects: performance modeling and optimization of ORC systems based on pure and zeotropic mixture working fluids; applications of waste heat recovery via ORC to gas turbines and reciprocating engines; optimal sizing and operation of ORC under combined heat and power and district heating application; the potential of ORC on board ships and related issues; life cycle analysis for biomass application; ORC integration with supercritical CO2 cycle; and the proper design of the main ORC components, including fluid dynamics issues. The current state of the art is considered and some cutting-edge ORC technology research activities are examined in this book.

  •  
    965

    Writing or managing a scientific book, as it is known today, depends on a series of major activities, such as regrouping researchers, reviewing chapters, informing and exchanging with contributors, and at the very least, motivating them to achieve the objective of publication. The idea of this book arose from many years of work in biomechanics, health disease, and rehabilitation. Through exchanges with authors from several countries, we learned much from each other, and we decided with the publisher to transfer this knowledge to readers interested in the current understanding of the impact of biomechanics in the analysis of movement and its optimization. The main objective is to provide some interesting articles that show the scope of biomechanical analysis and technologies in human behavior tasks. Engineers, researchers, and students from biomedical engineering and health sciences, as well as industrial professionals, can benefit from this compendium of knowledge about biomechanics applied to the human body.

  •  
    595

    This book provides recent studies focused on chemical biology and biocatalysis applied to organic synthesis. The articles range from topics such as fungal metabolism and fungi-mediated biotransformations to the exploitation of specific enzymes in biocatalyzed reactions, also including works on the characterization of enzymes and the study of their catalytic activity. Overall, ten studies are presented that provide the reader with relevant, fresh insights on the use of enzymes and on the importance of biocatalysis.

  •  
    685

    This Special Issue deals with improvements in the energy efficiency of electric devices, machines, and drives, which are achieved through improvements in the design, modelling, control, and operation of the system. Properly sized and placed coils of a welding transformer can reduce the required iron core size and improve the efficiency of the welding system operation. New structures of the single-phase field excited flux switching machine improve its performance in terms of torque, while having higher back-EMF and unbalanced electromagnetic forces. A properly designed rotor notch reduces the torque ripple and cogging torque of interior permanent magnet motors for the drive platform of electric vehicles, resulting in lower vibrations and noise. In the field of modelling, the torque estimation of a Halbach array surface permanent magnet motor with a non-overlapping winding layout was improved by introducing an analytical two-dimensional subdomain model. A general method for determining the magnetically nonlinear two-axis dynamic models of rotary and linear synchronous reluctance machines and synchronous permanent magnet machines is introduced that considers the effects of slotting, mutual interaction between the slots and permanent magnets, saturation, cross saturation, and end effects. Advanced modern control solutions, such as neural network-based model reference adaptive control, fuzzy control, senseless control, torque/speed tracking control derived from the 3D non-holonomic integrator, including drift terms, maximum torque per ampere, and maximum efficiency characteristics, are applied to improve drive performance and overall system operation.

  •  
    965

    In recent years, many technologies for gait and posture assessments have emerged. Wearable sensors, active and passive in-house monitors, and many combinations thereof all promise to provide accurate measures of physical activity, gait, and posture parameters. Motivated by market projections for wearable technologies and driven by recent technological innovations in wearable sensors (MEMs, electronic textiles, wireless communications, etc.), wearable health/performance research is growing rapidly and has the potential to transform future healthcare from disease treatment to disease prevention. The objective of this Special Issue is to address and disseminate the latest gait, posture, and activity monitoring systems as well as various mathematical models/methods that characterize mobility functions. This Special Issue focuses on wearable monitoring systems and physical sensors, and its mathematical models can be utilized in varied environments under varied conditions to monitor health and performance

  •  
    1 155

    This book provides a collection of comprehensive research articles on data analytics and applications of wearable devices in healthcare. This Special Issue presents 28 research studies from 137 authors representing 37 institutions from 19 countries. To facilitate the understanding of the research articles, we have organized the book to show various aspects covered in this field, such as eHealth, technology-integrated research, prediction models, rehabilitation studies, prototype systems, community health studies, ergonomics design systems, technology acceptance model evaluation studies, telemonitoring systems, warning systems, application of sensors in sports studies, clinical systems, feasibility studies, geographical location based systems, tracking systems, observational studies, risk assessment studies, human activity recognition systems, impact measurement systems, and a systematic review. We would like to take this opportunity to invite high quality research articles for our next Special Issue entitled "Digital Health and Smart Sensors for Better Management of Cancer and Chronic Diseases" as a part of Sensors journal.

  •  
    1 055

    In recent years, many technologies for gait and posture assessments have emerged. Wearable sensors, active and passive in-house monitors, and many combinations thereof all promise to provide accurate measures of physical activity, gait, and posture parameters. Motivated by market projections for wearable technologies and driven by recent technological innovations in wearable sensors (MEMs, electronic textiles, wireless communications, etc.), wearable health/performance research is growing rapidly and has the potential to transform future healthcare from disease treatment to disease prevention. The objective of this Special Issue is to address and disseminate the latest gait, posture, and activity monitoring systems as well as various mathematical models/methods that characterize mobility functions. This Special Issue focuses on wearable monitoring systems and physical sensors, and its mathematical models can be utilized in varied environments under varied conditions to monitor health and performance

  •  
    965

    In recent years, many technologies for gait and posture assessments have emerged. Wearable sensors, active and passive in-house monitors, and many combinations thereof all promise to provide accurate measures of physical activity, gait, and posture parameters. Motivated by market projections for wearable technologies and driven by recent technological innovations in wearable sensors (MEMs, electronic textiles, wireless communications, etc.), wearable health/performance research is growing rapidly and has the potential to transform future healthcare from disease treatment to disease prevention. The objective of this Special Issue is to address and disseminate the latest gait, posture, and activity monitoring systems as well as various mathematical models/methods that characterize mobility functions. This Special Issue focuses on wearable monitoring systems and physical sensors, and its mathematical models can be utilized in varied environments under varied conditions to monitor health and performance

  •  
    869

    MicroRNAs (miRNAs) are small noncoding RNAs that are 19-24 nucleotides in length, following maturation. Recent evidence has demonstrated their key role as post-transcriptional regulators of gene expression through the binding of specific sequences within target messenger RNA (mRNA). miRNAs are involved in the synthesis of a very large number of proteins, and it is speculated that they could regulate up to 30% of the human genome. They control virtually every cellular process and are essential for animal development, cell differentiation, and homeostasis. Altered miRNA expression has been linked to such pathological events as inflammatory, degenerative, or autoimmune processes and have been associated with several diseases, including cancer, cardiovascular diseases, diabetes mellitus, and rheumatic and neurological disorders. Recently, miRNAs have been found in many different biological fluids, and this observation suggests the potential of miRNAs as new candidate biomarkers for diagnosis, classification, prognosis, and responsiveness in the treatment of different pathological conditions. Furthermore, the development of therapeutic strategies that involve either restoring or repressing miRNAs expression and activity has attracted much attention. Significant progress has been made in the systems for delivery of miRNAs, even if substantial improvements in this area are still necessary. Although they have been extensively studied, a number of interesting questions regarding the physiological and pathological role of miRNAs have been postulated, and their potential diagnostic and therapeutic role remain yet unanswered. Reactive oxygen species (ROS) are free radical-containing oxygen molecules derived from cellular oxidative metabolism, including enzyme activities and mitochondrial respiration, and play a pivotal role in many cellular functions. Whereas ROS are essential for normal cellular processes, their aberrant production, or failure of the capacity to scavenge excessive ROS, induces an altered redox status with excessive synthesis of free radicals, leading to an imbalance in the redox environment of the cell. The loss of normal ROS levels causes lipid, protein, and DNA damage, which contribute to the development of various pathologies including neurological disorders, rheumatic and cardiovascular diseases, diabetes, and cancer. Increasing evidence highlights that there is crosstalk between miRNAs and components of redox signaling, even if this complex and the characteristics of mutual interaction need to be amply elucidated. Hence, both miRNAs and oxidative stress are involved in the multifactorial development and progression of acute and chronic diseases by influencing numerous signaling and metabolic pathways. The Special Issue entitled "Crosstalk between MicroRNA and Oxidative Stress in Physiology and Pathology" of the International Journal of Molecular Sciences includes original articles and reviews that provide new insights into the interaction between miRNAs and oxidative stress under normal and pathological conditions which can assist in the development of new therapeutic strategies. Finally, I would like to thank all the authors for their excellent contribution. I hope this Special Issue will provide readers with updated knowledge about the role of miRNAs and oxidative stress in physiology and pathology.

  •  
    869

    Food quality, safety, and fortification are key aspects to guarantee that foods reach consumers in optimal conditions from the point of view of freshness, microbiology, and health promotion. This book overviews the most recent fundamental and oriented efforts by multidisciplinary researchers and technologists on the application of nanoscience and nanotechnology to generate new added value solutions for the food industry. Nanomaterials to Enhance Food Quality, Safety, and Health Impact provides a valuable guide for both industry and academic researchers interested in the production of healthier, safer, and sustainable food products.

  •  
    595

    Polyamines are small organic compounds found in all living organisms. In recent years, there have been many exciting advances in our understanding of plant polyamines, such as the determination of the biosynthetic and catabolic pathways of plant polyamines and the identification of the roles that plant polyamines play in cellular processes. This Special Issue contains six original research papers and three review articles, providing valuable insights and information for future polyamine-related research.

  •  
    595

    The use of social media in public health education/promotion has been increasing due, in part, to its ability to remove physical access and geographical barriers for users. Specifically, social media provides an outlet to increase and promote translational health communication strategies and the effective dissemination of health information and data in ways that allow users to not only utilize, but also to create and share pertinent health information. Although social media applications in public health and health promotion have yielded success in terms of generating support structures and networks for effective health behavior change, there are challenges and complications associated with use of social media that also need to be addressed (e.g., managing misinformation, ensuring compliance with privacy protection regulations). This Special Issue aims to explore social media as a translational health promotion tool by bridging principles of health education and health communication. Broadly, this Special Issue is seeking original submissions that examine: (1) the method with which social media users access, negotiate, and create health information that is both actionable and impactful for diverse audiences; (2) strategies for overcoming challenges to using social media in health promotion; and (3) best practices for designing, implementing, and/or evaluating social media campaigns and forums in public health. Special interest will be given to innovative submissions that expand and build upon traditional health education approaches with health communication theories and models. Other manuscript types of interest include relevant position papers, brief reports, and commentaries.

  •  
    695

    "Earth Observations for Addressing Global Challenges" presents the results of cutting-edge research related to innovative techniques and approaches based on satellite remote sensing data, the acquisition of earth observations, and their applications in the contemporary practice of sustainable development.Addressing the urgent tasks of adaptation to climate change is one of the biggest global challenges for humanity. As His Excellency Ant├│nio Guterres, Secretary-General of the United Nations, said, "Climate change is the defining issue of our time-and we are at a defining moment. We face a direct existential threat." For many years, scientists from around the world have been conducting research on earth observations collecting vital data about the state of the earth environment. Evidence of the rapidly changing climate is alarming: according to the World Meteorological Organization, the past two decades included 18 of the warmest years since 1850, when records began. Thus, Group on Earth Observations (GEO) has launched initiatives across multiple societal benefit areas (agriculture, biodiversity, climate, disasters, ecosystems, energy, health, water, and weather), such as the Global Forest Observations Initiative, the GEO Carbon and GHG Initiative, the GEO Biodiversity Observation Network, and the GEO Blue Planet, among others. The results of research that addressed strategic priorities of these important initiatives are presented in the monograph.

  •  
    499

    The development of porous materials has attracted the attention of the research community for years. Porosity characteristics have specific impacts on the material properties and materials that are applied in many areas, such as pollutant removal, CO2 capture, energy storage, catalytic oxidation and reduction processes, the conversion of biomass to biofuels, and drug delivery. Examples of porous materials are activated carbons, clays, and zeolites. The aim of this book is to collect the recent advances and progress regarding porous materials and their applications in the environmental area.

  •  
    509

    Energy crises and global warming pose serious challenges to researchers in their attempt to develop a sustainable society for the future. Solar energy conversion is a remarkable, clean, and sustainable way to nullify the effects of fossil fuels. The findings of photocatalytic hydrogen production (PCHP) by Fujishima and Honda propose that "water will be the coal for the future". Hydrogen is a carbon-free clean fuel with a high specific energy of combustion. Titanium oxide (TiO2), graphitic-carbon nitride (g-C3N4) and cadmium sulfide (CdS) are three pillars of water splitting photocatalysts owing to their superior electronic and optical properties. Tremendous research efforts have been made in recent years to fabricate visible or solar-light, active photocatalysts. The significant features of various oxide, sulfide, and carbon based photocatalysts for cost-effective hydrogen production are presented in this Special Issue. The insights of sacrificial agents on the hydrogen production efficiency of catalysts are also presented in this issue.

  •  
    499

    Leonhard Euler (1707-1783) was born in Basel, Switzerland. Euler''s formula is a mathematical formula in complex analysis that establishes the fundamental relationship between the trigonometric functions and the complex exponential function. When its variable is the number pi, Euler''s formula evaluates to Euler''s identity. On the other hand, the Yang-Baxter equation is considered the most beautiful equation by many scholars. In this book, we study connections between Euler''s formulas and the Yang-Baxter equation. Other interesting sections include: non-associative algebras with metagroup relations; branching functions for admissible representations of affine Lie Algebras; super-Virasoro algebras; dual numbers; UJLA structures; etc.

  •  
    685

    Long-chain polyunsaturated fatty acids (PUFAs) of the omega-3 family, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are physiologically important for many animals and humans. Moreover, fatty acids play an important roles in numerous contexts reflecting various levels: from their producers in natural ecosystems, microalgae, through to invertebrates and fish, and to culinary treatments of fish products for human consumption. Environmental threats such as anthropogenic pollution and its effects on PUFA yield in aquatic ecosystems as well as their transfer to terrestrial ecosystems are highlighted. Assumptions and challenges that are important for the study of PUFA in trophic webs of aquatic ecosystems as well as in human nutrition are discussed.

  •  
    685

    High penetration of fluctuating renewable power units, such as wind turbines and photo voltaic systems, and new heavy loads, such as electrical vehicles and heat pumps, which so far might not be controlled according to the actual distribution grid condition, but rather according to actual consumption of the devices, influences the distribution grid in several ways, and it may lead to voltage disturbances, frequency deviations and harmonic content beyond limits. Over voltages might be generated at power production which is too high, whereas under voltage might occur at heavy load situations; both phenomena might be seen at the same distribution radial, where harmonic injections can also come from the devices, if equipped with power converters. This has led to the main target object for this book being power quality in distribution grids. This book offers 10 papers regarding power quality issues at distribution grids. It looks into hosting capacity issues, stability analysis, reliability assessment, mitigation of voltage rise using reactor installation, power quality assessments, harmonic analysis and damping, frequency control in weak and isolated power systems, and the focus is therefore broad within the overall topic of power quality.

  •  
    595

    In an effort to contribute to global efforts by addressing the marine pollution from various emission types, this Special Issue of Ship Lifecyle for Journal of Marine Science and Engineering was inspired to provide a comprehensive insight for naval architects, marine engineers, designers, shipyards, and ship-owners who strive to find optimal ways to survive in competitive markets by improving cycle time and the capacity to reduce design, production, and operation costs while pursuing zero emission. In this context, this Special Issue is devoted to providing insights into the latest research and technical developments on ship systems and operation with a life cycle point of view. The goal of this Special Issue is to bring together researchers from the whole marine and maritime community into a common forum to share cutting-edge research on cleaner shipping. It is strongly believed that such a joint effort will contribute to enhancing the sustainability of the marine and maritime activities. This Special Issue features six novel publications dedicated to this endeavor. First of all, as a proactive response to transitioning to cleaner marine fuel sources, numerous aspects of the excellence of fuel-cell based hybrid ships were demonstrated through four publications. In addition, two publications demonstrated the effectiveness of life cycle assessment (LCA) applicable to marine vessels.

  •  
    685

    This volume examines the applicability of nature-based solutions in ecological restoration practice and in contemporary landscape architecture by bringing together ecology and architecture in the built environment. Green infrastructure is used to address urban challenges such as climate change adaptation, disaster risk reduction, and stormwater management. In addition, thermal comfort nature-based solutions reintroduce critical connections between natural and urban systems. In light of ongoing developments in sustainable urban development, the goal is a paradigm shift towards a landscape that restores and rehabilitates urban ecosystems. The ten contributions to this book examine a wide range of successful cases of designing healthier, greener and more resilient landscapes in different geographical contexts, from the United States of America and Brazil, through various European regions, to Singapore and China. While some chapters attempt to conceptualize the interconnections between cities and nature, others clearly have an empirical focus. Therefore, this volume provides a rich body of work and acts as a starting point for further studies on restoration of ecosystems and integrative policies such as the United Nations Sustainable Development Goals.

  •  
    595

    Robotics and control are both research and application domains that have been frequently engineered through the use of interdisciplinary approaches like cybernetics. Cognition is a particular concept of this approach, abstracted from the context of living organisms to that of artificial devices, and is concerned with knowledge acquisition and understanding through thought, experience, and the senses. Cognitive robotics and control refer to knowledge processing as much as knowledge generation from problem understanding, leading to special forms of architectures that enable systems to behave in an autonomous way. The main aim of this book is to highlight emerging applications and address recent breakthroughs in the domain of cognitive robotics and control and related areas. Procedures, algorithms, architectures, and implementations for reasoning, problem solving, or decision making are considered in the domain of robotics and control.

  • av Sergio Escalera & Thomas Moeslund
    869

    This Special Issue focused on novel vision-based approaches, mainly related to computer vision and machine learning, for the automatic analysis of human behaviour. We solicited submissions on the following topics: information theory-based pattern classification, biometric recognition, multimodal human analysis, low resolution human activity analysis, face analysis, abnormal behaviour analysis, unsupervised human analysis scenarios, 3D/4D human pose and shape estimation, human analysis in virtual/augmented reality, affective computing, social signal processing, personality computing, activity recognition, human tracking in the wild, and application of information-theoretic concepts for human behaviour analysis. In the end, 15 papers were accepted for this special issue. These papers, that are reviewed in this editorial, analyse human behaviour from the aforementioned perspectives, defining in most of the cases the state of the art in their corresponding field.

  •  
    869

    Neurodegenerative diseases, including Alzheimer''s, Parkinson''s, Huntington''s, and amyotrophic lateral sclerosis, are the most common pathologies of the central nervous system currently without a cure. They share common molecular and cellular characteristics, including protein misfolding, mitochondrial dysfunction, glutamate toxicity, dysregulation of calcium homeostasis, oxidative stress, inflammation, and ageing, which contribute to neuronal death. Efforts to treat these diseases are often limited by their multifactorial etiology. Natural products, thanks to their multitarget activities, are considered promising alternatives for the treatment of neurodegeneration. This book deals with two different forms of natural products: extracts and isolated compounds. The study of the bioactivity of the extracts is extremely important as many studies have demonstrated the synergistic effect of the combination of different natural products. On the other hand, the investigation of the activity of specifically isolated natural products can be also important to understand their cellular and molecular mechanisms and to define the specific bioactive components in extracts or foods. This book can be considered an important contribution to knowledge of the neuroprotective effect of natural products and presents a great deal of information, related to both the benefits but also the limitations of their use in counteracting neurodegeneration.

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