Böcker utgivna av Elsevier Science

"Topics in Anti-Cancer Research covers new developments in the field of cancer. Novel drugs as anticancer agents include natural and synthetic phenazirines and other anti-cancer compounds. It also encompasses the role of estrogen as estrogen disruptor and strategies targeting cancer stem cells for the treatment of different types of cancer, including myeloma and renal cell cancer. The diversity of researches and topics published in this eBook Series will be valuable to our cancer researchers, clinicians, cancer professionals aiming to develop novel anti-cancer targets and patents for the treatment of various cancers. The topics covered in the Eighth Volume of this series are as follows: - Novel Drugs for Multiple Myeloma - Synthetic Estrogens are Endocrine Disruptors via Inhibition of AF1 Domain of ERs - Recent Progress of Phenazines as Anticancer Agents - Cancer Stem Cell Targeting for Anticancer Therapy: Strategies and Challenges"

This volume presents reviews of traditional Chinese medicine and other plant based therapies useful for treating different cancers. The topics included in this volume are: Herbal extracts from Carica papaya and Azadirachta Natural antimutagens Encapsulated polyphenols and other anticancer compounds derived from plants Traditional Chinese medicine treatments for cancer related fatigue Indirubins Ayurvedic anticancer herbal medicines Melanocyte regeneration through herbal medicine

Many herbs and spices, in addition to their culinary use for taste, contain chemical compounds which have medicinal uses. For this reason, herbs and spies have been used for treating various ailments since ancient times. Modern scientific methods have enabled researchers to isolate bioactive compounds from herbs and spices and perform chemical analyses, which can be used to develop medicines to treat different diseases. This book series is a compilation of current reviews on studies performed on herbs and spices. Science of Spices and Culinary Herbs is essential reading for medicinal chemists, herbalists and biomedical researchers interested in the science of natural herbs and spices that are common part of regional diets and folk medicine. The first volume of this series features the following reviews: 1. Saffron: The Golden Spice 2. The Effect of Crocus sativous (Saffron) on Respiratory System, Traditional and Experimental Evidences 3. Nutraceutical Activities of Turmeric (Curcuma longa) and its Bioactive Constituent Curcumin 4. Antibacterial and Anticancer Activities of Turmeric and its Active Ingredient Curcumin, and Mechanism of Action 5. Strategies for Enhancement of Bioavailability and Bioactivity of Curcumin 6. Effect of Curcumin on the Diversity of Gut Microbiota 7. Turmeric and Inflammatory Diseases: An Overview of Clinical Evidence 8. Pre-Clinical/Animal Studies Conducted on Turmeric and Curcumin and Their Formulations

Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field.This volume presents the following reviews: - Recent Progress on Asymmetric Synthesis of Chiral Flavanones, Chromanones, and Chromenes- Supramolecular Chemistry of Modified Amino Acids and Short Peptides- The Use of Nanocatalysts in the Synthesis of Heterocycles: A Contemporary Approach- Synthesis and Applications of 1,2,3-Triazoles- Ring C-H Functionalization of Aromatic N-Oxides

Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field.This volume presents the following reviews: o Organocatalytic α-hydroxylation or α-aminoxylation of Carbonyl Compoundso Achmatowicz Rearrangement Derived Synthons, and their Relevant Bioinspired Chemistryo Recent Advances in the Synthesis of N-Glycosyl Compoundso Acidic and Basic Functionalized Ionic Liquid Systems for Advanced Synthesis of Five and Six Membered Nitrogenates Heterocycleso Mesoporous SBA-15: A Superior Heterogeneous Catalytic Support for Multicomponent Organic Synthesis

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology. The sixth volume of this series features reviews that cover the following topics: -Depression, Insomnia and Atypical Antidepressants-Combination Therapy of Hypothermia for Hypoxic Encephalopathy in Neonates-Development of a "Theranostic Nano-Bullet" for Tinnitus-Dexmedetomidine: From Basic Science to Clinical Application of Brain Protection-Protein Misfolding, Aggregation, Amyloid Formation in Neurodegenerative Diseases

Characterization of Semiconductor Heterostructures and Nanostructures is structured so that each chapter is devoted to a specific characterization technique used in the understanding of the properties (structural, physical, chemical, electrical etc..) of semiconductor quantum wells and superlattices. An additional chapter is devoted to ab initio modeling. The book has two basic aims. The first is educational, providing the basic concepts of each of the selected techniques with an approach understandable by advanced students in Physics, Chemistry, Material Science, Engineering, Nanotechnology. The second aim is to provide a selected set of examples from the recent literature of the TOP results obtained with the specific technique in understanding the properties of semiconductor heterostructures and nanostructures. Each chapter has this double structure: the first part devoted to explain the basic concepts, and the second to the discussion of the most peculiar and innovative examples. The topic of quantum wells, wires and dots should be seen as a pretext of applying top level characterization techniques in understanding the structural, electronic etc properties of matter at the nanometer (and even sub-nanometer) scale. In this respect it is an essential reference in the much broader, and extremely hot, field of Nanotechnology. Comprehensive collection of the most powerful characterization techniques for semiconductors heterostructures and nanostructures Most of the chapters are authored by scientists that are world-wide among the top-ten in publication ranking of the specific field Each chapter starts with a didactic introduction on the technique The second part of each chapters deals with a selection of top examples highlighting the power of the specific technique to analyse the properties of semiconductors heterostructures and nanostructures

The Mekong River Basin: Ecohydrological Complexity from Catchment to Coast, Volume Three presents real facts, data and predictions for quantifying human-induced changes throughout the Mekong watershed, including its estuaries and coasts, and proposes solutions to decrease or mitigate the negative effect and enable sustainable development. This is the first work to link socio-ecological interaction study over the whole Mekong River basin through the lens of ecohydrology. Each chapter is written by a leading expert, with coverage on climate change, groundwater, land use, flooding drought, biodiversity and anthropological issues. Human activities are enormous in the whole watershed and are still increasing throughout the catchment, with severe negative impacts on natural resources are emerging. Among these activities, hydropower dams, especially a series of 11 dams in China, are the most critical as they generate massive changes throughout the system, including in the delta and to the livelihoods of millions of people and they threaten sustainability.

Algae Based Bioelectrochemical Systems for Carbon Sequestration, Carbon Storage, Bioremediation and Bioproduct Generation explores the integration of carbon capture, storage and sequestration technologies with bioelectrochemical fuels cells (BEFC), showing how conventional technologies can be renovated to aid in the reduction in GHG emissions and simultaneously optimize BEFC performance. The book focuses on the integration of algal biogas upgradation with electrochemical systems, providing a guide to the renovation of conventional technologies to combine energy production and carbon sequestration. Chapters discuss the latest advancements in carbon sequestration biocatalyst and microbial platforms and integrations for rapid carbon biotransformations. In addition, the book highlights the potential of algae and chemolithotrophs as candidates for carbon delivery, biocatalyst orientation and architecture for optimal BEFC performance.

Managed Pressure Drilling Fundamentals, Methods and Applications, First Edition provides the basic infrastructure and extended support necessary for drilling engineers to apply managed pressure drilling to their operations. Enhanced with multiple new chapters and contributions from both academic and corporate authors, this reference provides engineers with the basic processes and equipment behind MPD. Other sections explain the latest technology and real-world case studies, such as how to optimize the managed pressure drilling system, how to choose the best well candidate for MPD, and how to lower costs for land-based operations. Packed with a glossary, list of standards, and a well classification system, this book is a flagship reference for drilling engineers on how to understand basics and advances in this fast-paced area of oil and gas technology.

Advances in Cold Spray: A Coating Deposition and Additive Manufacturing Process, Second Edition reviews the fundamental processes and recent advances made in the field of cold spray. This fully updated edition now includes a special chapter on Cold Spray Additive Manufacturing, along with advancements in impact modeling and simulation that allow a better understanding of the cold spray bonding mechanisms, powder synthesis and predictive modeling to improve the engineering of cold spray powders. In addition, materials properties data is a backbone of this book because the advanced cold spray materials have proven to be comparable to wrought and enable cold spray to be incorporated into structural applications for near-net shape parts production as well as for repair. Finally, numerous modern applications of cold spray representative of the Electronics, Medical, Petrochemical, Nuclear, Aerospace, Automotive, and Additive Manufacturing industries are presented.

The transformation of polysaccharides into valuable compounds for health and industry requires the careful application of enzyme protocols and controlled biocatalysis. Polysaccharide-Degrading Biocatalysts provides a thorough grounding in these biocatalytic processes and their growing role in the depolymerization of polysaccharides, empowering researchers to discover and develop new enzyme-based approaches across pharmaceuticals, fuels, and food engineering. Here, over a dozen leading experts offer a close examination of structural polysaccharides, genetic modification of polysaccharides, polysaccharide degradation routes, pretreatments for enzymatic hydrolysis, hemicellulose-degrading enzymes, biomass valorization processes, oligosaccharide production, and enzyme immobilization for the hydrolysis of polysaccharides, among other topics and related research protocols. A final chapter considers perspectives and challenges in an evolving, carbohydrate-based economy.

GaN Transistor Modeling for RF and Power Electronics: Using The ASM-GaN-HEMT Model covers all aspects of characterization and modeling of GaN transistors for both RF and Power electronics applications. Chapters cover an in-depth analysis of the industry standard compact model ASM-HEMT for GaN transistors. The book details the core surface-potential calculations and a variety of real device effects, including trapping, self-heating, field plate effects, and more to replicate realistic device behavior. The authors also include chapters on step-by-step parameter extraction procedures for the ASM-HEMT model and benchmark test results. GaN is the fastest emerging technology for RF circuits as well as power electronics. This technology is going to grow at an exponential rate over the next decade. This book is envisioned to serve as an excellent reference for the emerging GaN technology, especially for circuit designers, materials science specialists, device engineers and academic researchers and students.

Disposal and Recycling Strategies for Nano-engineered Materials enables the reader to understand and implement the latest methods for the safe disposal and re-use of nanomaterials found in the environment at end-of-life. Sections introduce nanomaterials, their general classification, properties, and preparation techniques before providing an overview and analysis of common disposal strategies. This is followed by in-depth chapters that focus on important steps and innovative strategies in dealing with waste nanomaterials, including sampling, classification and identification of waste materials, green technologies and biodegradation strategies, physico-chemical disposal, integrated technologies to prevent or control nanomaterial wastes entering the environment, and more. This is a valuable resource for researchers, advanced students, engineers, and scientists, with an interest in nanomaterials, their life cycle, waste, and recycling, water treatment, chemical engineering, environmental science, materials science, chemistry, and sustainability.

Neuromorphic Photonic Devices and Applications synthesizes in one volume the most critical advances in photonic neuromorphic models, photonic material platforms, and accelerators for neuromorphic computing. It discusses fields and applications that can leverage these new platforms. A brief review of the historical development of the field is provided followed by a discussion of the emerging 2D photonic materials platforms and recent work in implementing neuromorphic models and 3D neuromorphic systems. The application of artificial intelligence such as neuromorphic models to inverse design neuromorphic materials and devices and predict performance challenges is discussed throughout. The book includes a comprehensive overview of the applications of neuromorphic photonic technologies and the challenges, opportunities, and future prospects facing the field. Neuromorphic Photonic Devices and Applications is suitable for researchers and practitioners in academia and R&D in the multi-disciplinary field of photonics.

Biomedical Engineering Modeling of Pancreatic, Respiratory, and Renal Regulatory Systems, and their Medical Assessments addresses the need for biomedical engineering to provide physiological analysis of organ systems and their medical applications to help enable quantitative formulation of physiological systems and defining their functions and dysfunctions, leading to precision diagnostics of diabetes, lung diseases, and kidney failure, often in the form of non-dimensional indices. The book chapters also deal with treatment systems, namely automated insulin infusion systems, hemodialysis, and peritoneal dialysis. The book is formulated to solve many physiological, bioengineering, and medical problems.

XAI Based Intelligent Systems for Society 5.0 focuses on the development and analysis of Explainable Artificial Intelligence (XAI)-based models and intelligent systems that can be utilized for Society 5.0-characterized by a knowledge intensive, data driven, and non-monetary society. The book delves into the issues of transparency, explainability, data fusion, and interpretability, which are significant for the development of a super smart society and are addressed through XAI-based models and techniques. XAI-based deep learning models, fuzzy and hybrid intelligent systems, expert systems, and intrinsic explainable models in the context of Society 5.0 are presented in detail.The book also addresses-using XAI-based intelligent techniques-the privacy issues intrinsic in storing huge amounts of data or information in virtual space. The concept of Responsible AI, which is at the core of the future direction of XAI for Society 5.0, is also explored in this book. Finally, the application areas of XAI, including relevant case studies, are presented in the concluding chapter. This book serves as a valuable resource for graduate/post graduate students, academicians, analysts, computer scientists, engineers, researchers, professionals, and other personnel working in the area of artificial intelligence, machine learning, and intelligent systems, who are interested in creating a people-centric smart society.

Transpathology: Molecular Imaging-Based Pathology is a multidisciplinary reference on molecular imaging and pathology. The book is intended for professionals in the fields of molecular imaging, nuclear medicine, radiology, and pathology as well as students and clinical residents. The book describes the importance of non-invasive diagnosis-based precision medicine and presents a detailed description of current transpathological approaches in different aspects essential for the future development of precision medicine. It is molecular imaging approach to experimental research and clinical practice which will drive the field forward and improve research outcomes.