Böcker utgivna av Elsevier Science

The Neuroscience of Bach's Music: Perception, Action, and Cognition Effects on the Brain is a comprehensive study of Johann Sebastian Bach's music through the lens of neuroscience, examining neuroscience using Bach's music as a tool. This book synthesizes cognitive neuroscience, music theory, and musicology to provide insights into human cognition and perception. It also explores how a neuroscience perspective can improve listening and performing experiences for Bach's music. Written by a physician-neuroscientist recognized for scholarly articles on Bach's music, this book uses specific examples to explore neuroscience across Bach's compositions. The book is structured to discuss the brain's action, perception, and cognition as connected to specific Bach concertos, tones, notes, and performances. Two guest contributors provide insight into exact mathematical, or topologic, and music theoretic aspects of Bach's music with implications for cognitive neuroscience.

Microbial Biostimulants for Plant Growth and Abiotic Stress Amelioration, the latest release in the Biostimulants and Protective Biochemical Agents series, provides readers with insights into the major role of biostimulants in plant growth and development while under abiotic stress. The term biostimulants is broadly used to reference a group of diverse substances and microorganisms that stimulate life or that promote favorable plant responses. They stimulate natural processes to enhance/benefit nutrient uptake, nutrient efficiency, tolerance to abiotic stress, and crop quality. Many biostimulants improve nutrition and they do so regardless of their own nutrient contents. Further, recently microbe-based biostimulants have emerged as important plant protectors under a range of adverse conditions.

"Illustrated by the world-renowned Frank H. Netter, MD and artists working in his tradition, Netter's Atlas of Human Embryology, 2nd Edition, provides a rich pictorial overview of human prenatal development. For each stage of development and for each body system, you'll find a brief description of the developmental plan, with key concepts and terminology, followed by discussions of histological principles, the classification of congenital anomalies, and basic cellular, molecular, and genetic concepts. An emphasis on morphological patterns in the embryo and fetus makes it easy to understand the structure and function of the adult body and the embryonic basis of natural variation as well as birth anomalies." --

Succinct yet comprehensive, Aminoff's Diagnosis of Neuromuscular Disorders, 4th Edition, provides expert information and guidance on the clinical, electrodiagnostic, and imaging aspects of neuromuscular disorders. Fully updated, it reflects important advances in the field, including an improved understanding of the molecular and genetic basis of neuromuscular disease, an expanded use of next-generation genetic testing, refinements in electrodiagnosis, and the use of ultrasound imaging techniques to evaluate the peripheral nervous system. In-depth discussions of disease states, as well as the evidence supporting the use of electrodiagnostic and imaging techniques, moves this reference from simply answering the question "How?" to also answering "Why?"Describes the range of clinical manifestations of individual neuromuscular diseases; the power and limitations of electrodiagnostic techniques as they relate to neuromuscular disorders; the place of genetic studies in the diagnosis and prognostication of these diseases; and the scope and utility of newer imaging procedures in detecting and localizing the underlying pathologic process.Reviews neuromuscular physiology and the pathology of major diseases.Provides a readable, well-illustrated synthesis of clinical and investigative techniques in diagnosing neuromuscular diseases, with concise guidance on how to conduct clinical, electrodiagnostic, and ultrasound evaluations and the findings in various disease states.Covers a wide variety of electrodiagnostic and ultrasound procedures, including techniques for evaluating different individual nerves.Features video clips of waveforms and of ultrasound images to illustrate key concepts.An ideal resource for neuromuscular specialists, clinical neurologists, physiatrists, rehabilitation specialists, clinical neurophysiologists, and electromyographers, as well as trainees and those preparing for board certification in neurology, PM&R, neuromuscular medicine, clinical neurophysiology, and electrodiagnostic medicine.An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Any additional digital ancillary content may publish up to 6 weeks following the publication date.

Translational Orthopedics: Designing and Conducting Translational Research covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. Readers will come to fully understand important concepts, including case-control study, prospective cohort study, randomized trial, and reliability study. Medical researchers will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in translational orthopedics, and know what is needed in collaboration. Further, this title is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps the aspiring investigator navigate challenging considerations in study design and implementation. The book provides valuable discussions of the critical appraisal of published studies in translational orthopedics, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every Medical Researcher or Orthopedist who has ever had a good clinical idea but not the knowledge of how to test it.

Microbiome-Assisted Bioremediation: Rehabilitating Agricultural Soils provides a complete reference on the opportunities, technologies, and challenges of remediating contaminated soils through use of microbial means. Environmental pollution and human exposure associated with heavy metals are attributed to anthropogenic activities such as mining, industrial wastes, and metal containing compounds in domestic and agricultural systems. Addressing the foundational aspects of microbe-based approaches, this book provides a valuable gateway resource for those entering the field, as well as providing in-depth insights into the various tools and techniques for real-world application. Microbial remediation has appeared as a promising approach to lessen the heavy metal concentration in the environment due to their sequestration and transforming ability of xenobiotic compounds. Microbial bioremediation is an efficient, economical, and environmentally-friendly procedure that reduces the cost of the cleanup process associated with heavy and toxic metal contamination.

Développez les compétences pour comprendre et soigner une grande diversité de patients ! Le Guide du professionnel de la santé sur la compétence culturelle, 2e édition explique la prestation de soins interculturels sûrs et efficaces. Ce livre met la théorie en pratique en commençant par un aperçu de la compétence culturelle clinique. Il montre comment appliquer la compétence culturelle à diverses populations et discute des considérations à prendre en travaillant avec des populations précises. Avec cette approche, vous développerez un ensemble de comportements, d'attitudes et de principes grâce auxquels vous travaillerez efficacement dans de nombreux milieux. Rédigé par une équipe d'auteur·e·s dirigée par Rani H. Srivastava, ce guide améliorera votre prise en charge des Autochtones, des membres de la communauté 2ELGBTQ+I, de personnes racisées, d'immigrants et de réfugiés. NOUVEAU! Cette édition est enrichie de nouveaux chapitres sur la santé des Autochtones, la diversité sexuelle et de genre, la santé des immigrants et des réfugiés, et la santé communautaire, ainsi que de nouveaux sujet tels que la sécurité culturelle, l'humilité culturelle, les impacts du racisme, le travail avec les interprètes, l'utilisation de la technologie et les soins palliatifs. NOUVEAU! UNIQUE! Des perspectives sur la compétence et la sécurité culturelles tout au long du texte vous permettront de fournir des soins culturellement sûrs et d'atteindre votre objectif d'apporter des soins équitables et appropriés sur le plan culturel. NOUVEAU! Une discussion sur les questions culturelles aborde le pouvoir, les privilèges, l'intersectionnalité, l'équité, la défense des droits et comment être un allié. NOUVEAU! Un contenu à jour comprend les dernières statistiques, lignes directrices, recherches, références et ressources. NOUVEAU! Le site Web Evolve améliore votre compréhension des questions de révision, des études de cas plausibles, et plus encore. Une approche UNIQUE aborde les populations telles que les travailleurs de la santé les rencontrent, et non en fonction d'étiquettes ethnoculturelles ou religieuses. Un style d'écriture accessible transmet l'information d'une manière équilibrée et concise pour les étudiants de premier et de deuxième cycle, ainsi que pour les professionnels de la santé. Une perspective multidisciplinaire grâce à des auteur·e·s qui représentent des disciplines de la santé et des identités culturelles diverses, qui travaillent en éducation ou en prestation de soins de la santé, et qui présentent des idées complexes de manière compréhensible et des idées controversées de manière transparente. Des encadrés Considérations culturelles dans les soins et Compétence culturelles en action qui associent la théorie à la pratique et invitent à une autoréflexion critique. Parmi les outils d'enseignement et d'apprentissage, chaque début de chapitre offre des objectifs d'apprentissage et des termes clés, chaque fin de chapitre propose des activités de groupe sont proposées, ainsi que des questions de révision et plus encore. NOUVEAU! Cette édition est enrichie de nouveaux chapitres sur la santé des Autochtones, la diversité sexuelle et de genre, la santé des immigrants et des réfugiés, et la santé communautaire, ainsi que de nouveaux sujet tels que la sécurité culturelle, l'humilité culturelle, les impacts du racisme, le travail avec les interprètes, l'utilisation de la technologie et les soins palliatifs. NOUVEAU! UNIQUE! Des perspectives sur la compétence et la sécurisation culturelles tout au long du texte vous permettront de fournir des soins culturellement sécuritaires et d'atteindre votre objectif d'apporter des soins équitables et appropriés sur le plan culturel. NOUVEAU! Une discussion sur les questions culturelles aborde le pouvoir, les privilèges, l'intersectionnalité, l'équité, la défense des droits et comment être un allié. NOUVEAU! Un contenu à jour comprend les dernières statistiques, lignes directrices, recherches, références et ressources. NOUVEAU! Le site Web Evolve améliore votre compréhension des questions de révision, des études de cas plausibles, et plus encore.

**Selected for Doody's Core Titles® 2024 in Physical Therapy** With a focus on the normal and abnormal mechanical interactions between the muscles and joints of the body, Neumann's Kinesiology of the Musculoskeletal System, 4th Edition provides a foundation for the practice of physical rehabilitation. This comprehensive, research-based core text explores kinesiology as it relates to physical rehabilitation in a clinically relevant and accessible manner. It presents the language of human movement - and acts as a bridge between basic science and clinical management. It helps clinicians effectively address the mechanical-based changes in movement across a person's lifespan, whether in the context of rehabilitation, recreation, or promotion of health and wellness. Full-color anatomic and kinesiologic illustrations clearly demonstrate the anatomy, functional movement, and biomechanical principles underlying movement and posture. An eBook version, included with print purchase, provides access to all the text, figures, and references, with the ability to search, customize content, make notes and highlights, and have content read aloud. The eBook included with print purchase also features multiple excellent videos of anatomic and kinesiologic principles, answers to study questions from the print book, and additional tables and figures. Evidence-based approach emphasizes the importance of research in PT decision-making. More than 900 high-quality illustrations provide visual accompaniments to clarify the material. Clinical Connections boxes at the end of each chapter highlight or expand upon a particular clinical concept associated with the kinesiology covered in the chapter. Special Focus boxes throughout the text provide numerous clinical examples to demonstrate why kinesiologic information is needed. Critical thinking questions for selected chapters reinforce the main concepts. UPDATED! Current, evidence-based content closes the gap in kinesiology and anatomy science with clinical practice. NEW! Additional Special Focus boxes and Clinical Connections boxes present kinesiology in a clinical context. UPDATED! Modified artwork and new figures visually reinforce key concepts. NEW! An eBook version, included with print purchase, provides access to all the text, figures, and references, with the ability to search, customize content, make notes and highlights, and have content read aloud. It also features videos, answers to study questions from the print book, and additional tables and figures.

OrthoBiologics provides state-of-the-art knowledge of current biologic therapies for a variety of orthopaedic conditions in a single source. The content is presented in a straightforward manner, including defining all currently available orthobiologic options, discussing processing characteristics and appropriate clinical use, and finally, summarizing clinical applications and outcomes as well as future potential directions. In addition to covering current approaches and applications, the editors aim for this book to present "best practices" for those practicing and researching orthopaedic pathologies and orthobiologic treatments, including blood and cellular based therapies. The editors are world-renown experts in the field and this book fills a gap in the market.

Haschek and Rousseaux's Handbook of Toxicologic Pathology, Fourth Edition, Volume Five: Toxicologic Pathology of Organ Systems is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals, and biologics. This book continues coverage of Organ-Specific Toxicologic Pathology and major organ systems not covered in Volume Four, and has been completely revised, making it an essential part of the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants.

Design and Analysis of Liquid Hydrogen Technologies: Liquefaction, Storage and Distribution offers readers a comprehensive guide to the development, analysis, design, and assessment methodologies for liquid hydrogen. From the fundamentals to the latest developments and current applications, the book provides an extensive and systematic discussion of the design, simulation, and techno-economic analysis methodologies that is supported by practical examples, verified codes, and innovative process designs. The book provides a comprehensive overview of the liquid hydrogen economy that is followed by advanced thermoeconomic, exergoeconomic, optimization, and dynamic simulation models that are essential for current and future LH2 technologies. Readers will find this to be a valuable resource for students, researchers, scientists, and engineers working in the hydrogen economy or involved in the processing, design, manufacturing, quality control, reliability, safety, systems, and testing of cryogenic refrigeration and liquid hydrogen production, storage, and transportation.

Neurobiology of Infectious Diseases covers mechanisms underlying infectious diseases. It is divided into six distinct sections, beginning with the foundations of Neuroinfection. This section includes chapters on the role microbiota-gut-brain axis and specialized blood-neuronal barriers play in neurobiology of infectious diseases. The next three sections detail various bacterial infections, parasitic infections, viral infections, and fungal infections of the central nervous system. The last section reviews the proteins and other peripheral mediators that affect the central nervous system. Internationally contributed by experts in the field this book sets the foundation of neurobiology and infectious disease. Neurobiology is the study of cells of the nervous system and the organization of these cells into functional circuits that process information and mediate behavior. Current research is vital for determining pharmaceutical and medicinal treatments for neurological disorders, psychiatric disorders and diseases.

Learning Deep Brain Stimulation Management through Clinical Cases reviews the clinical practice of applying deep brain stimulation (DBS) to patients with movement disorders. The book explores the cardinal aspects of applying DBS in diverse movement disorders based on patient’s needs. Every case answers all questions, providing case descriptions and step-by-step procedures for optimal replication. Every chapter includes a clinical decision support system (CDSS) depicted in flowcharts that can be used for reference. Deep Brain Stimulation (DBS) uses electrical stimulation to regulate electrical signals in neural circuits to and from identified areas in the brain to improve movement symptoms. The management of DBS in a movement disorders can be challenging, optimizing patient journeys and grasping all clinical aspects of the highly technological therapy. Hence, this book provides the informaiton necessary to embrace new breakthroughs.

Protein Misfolding in Neurodegenerative Diseases is a comprehensive review of proteome homeostasis in neurons, and in the brain. Beginning with an introduction on factors involved in the formation and aggregation of misfolded proteins, chapters then discuss the precise cellular and molecular mechanisms involved in these processes and their role in neurodegeneration and disease. Additional topics of focus include protein clearance mechanisms like protein quality control, disease-modifiers, molecular druggable targets, novel therapeutics, and emerging techniques that block or delay disease onset or progression. This volume is relevant for researchers working with neurodegenerative diseases, including Alzheimer's disease, Parkinson’s disease, ALS, Creutzfeldt-Jakob disease, and more.

Intelligent Fractal-Based Image Analysis: Application in Pattern Recognition and Machine Vision provides insights into the current strengths and weaknesses of different applications as well as research findings on fractal graphics in engineering and science applications. The book aims to improve the exchange of ideas and coherence between various core computing methods and highlights the relevance of related application areas for advanced as well as novice-user application. The book presents core concepts, methodological aspects, and advanced feature opportunities, focusing on major, real-time applications in engineering and health science. It will appeal to researchers, data scientists, industry professionals, and graduate students. Fractals are infinite, complex patterns used in modeling physical and dynamic systems. Fractal theory research has increased across different fields of applications including engineering science, health science, and social science. Recent literature shows the vital role fractals play in digital image analysis, specifically in biomedical image processing. Fractal graphics is an interdisciplinary field that deals with how computers can be used to gain high-level understanding from digital images. Integrating artificial intelligence with fractal characteristics has resulted in new interdisciplinary research in the fields of pattern recognition and image processing analysis.

Drug-delivery Systems of Phytochemicals as Therapeutic Strategies in Cancer Therapy elucidates the importance of various phytochemicals in cancer therapy and explains various routes/methods to deliver phytochemicals for overcoming the problems associated with delivery systems in cancer treatment. Several nanotechnological methods are presented to enhance drug solubility, sustainability, bioavailability, and gastrointestinal permeability of these phytochemicals. Current understanding of the relevant information presented on therapeutic strategies in cancer therapy fulfils the requirements of oncologists, molecular biologists, pharmacologist and related researchers who want to work in the areas of drug development targeting phytochemicals for cancer therapy.

Spinel Materials: Synthesis, Characterization, and Applications reviews the key principles, methods, applications, and research directions of spinel materials. Fundamental aspects such as the relationship between their size, metal ion occupancy, and physical behavior are introduced. Then, the synthesis methods to produce these materials and characterization methods used to observe their behaviors are reviewed. The electronic, optical, and magnetic properties of spinel materials make them suitable for wide range of uses, but especially for energy applications. The book reviews the most relevant opportunities and challenges of the use of spinel materials for energy applications.This resource is suitable for researchers and practitioners working in the subject area of materials science and engineering, and may also be of interest to those working in chemistry or physics disciplines.

Proteomics, Multi-Omics and Systems Biology in Optic Nerve Regeneration is a comprehensive reference that covers all vistas of standardization of axon regeneration, as well as all multi-omics and system level data and integration tools. By adopting a translational approach, the book bridges current research in the field to clinical applications, and readers can expect to learn standardization approaches for axon regeneration, multi-omics datasets, different databases, search engines, multiple dataset integrative tools, pathway convergence approaches and tools, outcome and outcome measures that unify bench research with clinical outcome. The axon regeneration from existing neurons in central nervous system (CNS) have become a potential possibility in the last decade. The potential possibility of long-distance axon growth has opened the possibility of re-connectivity of axons of retinal ganglion cell neurons within the lateral geniculate nucleus in the brain. The long-distance axon regeneration and re-connectivity is a promise to restore lost vision in the optic nerve. Further, long-distance regeneration and re-innervation is equally helpful for other fields such as spinal cord injuries.

The field molecular pathway analysis evolves rapidly, and many progressive methods have recently been discovered. Molecular Pathway Analysis Using High-Throughput OMICS Data contains the largest collections of molecular pathways. For the first time, guidelines on how to do genomic, epigenetic, transcriptomic, proteomic, and metabolomic data analysis in real-world research practice are given. Molecular Pathway Analysis Using High-Throughput OMICS Molecular Data also focuses on the pathway analysis applications for solving tasks in biotechnology, pharmaceutics, and molecular diagnostics ¿¿It demonstrates how pathway analysis can be applied for the research and treatment of chronic and acute diseases, for next-generation molecular diagnostics, for drug design and preclinical testing; relevant real-world examples, molecular tests, and web resources will be reviewed in-depth.¿ ¿¿The book shows a tendency of erasing the borders between chemistry, physics, informatics, mathematics, biology, and medicine by means of novel research approaches and instruments, providing a truly multidisciplinary approach.

Hybrid Polymeric Systems for Biomedical Applications explores the development and utilization of hybrid polymeric systems for use in a range of biomedical applications. Hybrid systems combine the specialized properties of each polymer type to produce a more targeted material which is much more tightly aligned with the intended application and outcome. This book covers a broad selection of hybrid polymeric systems as well as a variety of key biomedical applications, including tissue engineering, drug delivery, wound healing, and more.

Technical Organic and Inorganic Fibres from Natural Resources focuses on recent advances in the synthesis, processing, characterization, and application of non-textile fibers. The book provides a general introduction to the uses of natural fibers in technical textile applications while also reviewing the latest technical methods for producing these high-performance materials. As the textile industry is focused on finding alternative green fibers with the aim of providing high quality products which are fully recyclable and biodegradable, natural fibers from renewable sources play an increasingly important role in the industry due to their unique properties and functionality.

Cancer Therapy: Potential Applications of Nanotechnology provides readers with a compendium of all the latest research work in cancer therapeutics, including an emphasis on work in nanotechnology and polymeric nanoparticles. While there have been a large number of ongoing research projects and publications on the treatment of cancer, there is a limited number of books related to nanotechnology, especially those with an emphasis on polymeric nanoparticles in cancer therapy. This title enlightens researchers and students and provides exhaustive knowledge on the topics covered.

Self-powered Sensors: A Path to Wearable Electronics features recent developments in chemical, photonic, pharmaceutical, microbiological, biomimetic, and bio-inspired approaches for MEMS/NEMS and medicinal self-powered sensors. Unconventional nanomaterial sensors driven by self-sufficient energy are given a contemporary review, with a focus on the categorization of energy sources and comparisons of research involving self-powered solar, piezoresistive, triboelectric, and thermodynamic technologies. This book also focuses on the different techniques, materials, comparisons of fabrication of self-powered sensors as well as thermoelectric self-powered sensors and its implantable applications.

Plant Function Traits: Linking Climate and Ecosystem Functioning, part of the Plant Biology, Sustainability and Climate Change series, presents a wholistic understanding of Plant Functional Traits. As global climate change advances, natural resources are facing increasing survival challenges, hence this book directly addresses that need, exploring the morphological, physiological, and phenological properties of a plant that can be used as a proxy to understand plant environment interactions. Users will find great illustrations throughout individual chapters, along with case studies that demonstrate applications of functional traits in classifying vegetation of a region into distinct type groups as Plant Functional Types (PFTs). Additional information includes applications in the development of new generation of Dynamic Global Vegetation Model (DGVM) and an understanding of the response of vegetation to changing environments.

Nonclinical Development of Biologics, Vaccines and Specialty Biologics, Second Edition, is a complete reference devoted to the nonclinical safety assessment of novel biopharmaceuticals, vaccines, cell and gene therapies, and oncology therapeutics. Updated and revised, the new edition compares and contrasts these types of biologics with one another and with small molecule drugs, while incorporating the most current and essential international regulatory guidelines. This book discusses the different types of biologics, as well as early characterization strategies, principles of study design, nonclinical pharmacokinetics and pharmacodynamics, nonclinical assays, and regulatory guidelines. A coedited book with chapters authored by leading experts in the field, this comprehensive reference provides critical insights to all researchers involved in early through late-stage biologics.

Complex and Composite Metal Oxides for Gas, VOC, and Humidity Sensors, Volume 2: Technology and New Trends provides an overview of the advanced nanocomposite metal oxide materials used in sensors for environmental monitoring applications. Volume 2 discusses the state of the art in synthesis methods of innovative morphology, metal oxide hybrids, and heterostructures. It also describes the new generation of complex materials such as perovskites, spinel ferrites, and quaternary type-based gas and VOC sensors. This volume includes a brief discussion of advanced strategies for the development of futuristic sensors with properties such as room temperature operation, self-power generation, self-healability, flexibility, and wearability.

Handbook of MRI Pulse Sequences, Second Edition includes 92 self-contained sections, with each section focusing on a single subject. A new section on detailing the advanced pulse sequence techniques covers a variety of basic and advanced image reconstruction methods. The extensive topic coverage and cross-referencing makes this book ideal for beginners learning the building blocks of MRI pulse sequence design, as well as for experienced professionals who are seeking deeper knowledge of a particular technique. This book is among the most important medical imaging techniques available today. Each of these scanners is capable of running many different "pulse sequences." These sequences are governed by physics and engineering principles and implemented by software programs that control the MRI hardware.

Neuro-oncology broadly encompasses life-threatening brain and spinal cord malignancies, including primary lesions and lesions metastasizing to the central nervous system. It is well suited for diagnosis, classification, and prognosis as well as assessing treatment response. Radiomics and Radiogenomics (R-n-R) have become two central pillars in precision medicine for neuro-oncology. Radiomics is an approach to medical imaging used to extract many quantitative imaging features using different data characterization algorithms, while Radiogenomics, which has recently emerged as a novel mechanism in neuro-oncology research, focuses on the relationship of imaging phenotype and genetics of cancer. Due to the exponential progress of different computational algorithms, AI methods are composed to advance the precision of diagnostic and therapeutic approaches in neuro-oncology. The field of radiomics has been and definitely will remain at the lead of this emerging discipline due to its efficiency in the field of neuro-oncology. Several AI approaches applied to conventional and advanced medical imaging data from the perspective of radiomics are very efficient for tasks such as survival prediction, heterogeneity analysis of cancer, pseudo progression analysis, and infiltrating tumors. Radiogenomics advances our understanding and knowledge of cancer biology, letting noninvasive sampling of the molecular atmosphere with high spatial resolution along with a systems-level understanding of causal heterogeneous molecular and cellular processes. These AI-based R-n-R tools have the potential to stratify patients into more precise initial diagnostic and therapeutic pathways and permit better dynamic treatment monitoring in this period of personalized medicine. While extremely promising, the clinical acceptance of R-n-R methods and approaches will primarily hinge on their resilience to non-standardization across imaging protocols and their capability to show reproducibility across large multi-institutional cohorts. Radiomics and Radiogenomics in Neuro-Oncology: An Artificial Intelligence Paradigm ¿ Volume 2: Genetics and Clinical Applications provides readers with a broad and detailed framework for R-n-R approaches with AI in neuro-oncology, the description of cancer biology and genomics study of cancer, and the methods usually implemented for analyzing. Readers will also learn about the current solutions R-n-R can offer for personalized treatments of patients, limitations, and prospects. There is comprehensive coverage of information based on radiomics, radiogenomics, cancer biology, and medical image analysis viewpoints on neuro-oncology, so this in-depth coverage is divided into two Volumes. Volume 1: Radiogenomics Flow Using Artificial Intelligence provides coverage of genomics and molecular study of brain cancer, medical imaging modalities and analysis in neuro-oncology, and prognostic and predictive models using radiomics. Volume 2: Genetics and Clinical Applications provides coverage of imaging signatures for brain cancer molecular characteristics, clinical applications of R-n-R in neuro-oncology, and Machine Learning and Deep Learning AI approaches for R-n-R in neuro-oncology.

In this issue of Dermatologic Clinics, guest editor Dr. Hassan Galadari brings his considerable expertise to the topic of Hot Topics in Cosmetic Dermatology. Top experts cover key topics such as neurotoxin in the lower third of the face; chemical peels in the treatment of melasma; management of under eye darkness and wrinkles; facial overfilled syndrome; the needle vs. cannula debate in soft tissue augmentation; achieving the attractive Asian midface profile with hyaluronic acid-based fillers; and more.Contains 17 relevant, practice-oriented topics including updates on lasers in dermatology; update in assessment and treatment of botulinum toxin in the upper face; cosmetic dermatology in skin of color; management of cellulite; the effect of cosmetic procedures on the youth; and more.Provides in-depth clinical reviews on hot topics in cosmetic dermatology, offering actionable insights for clinical practice.Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Multi-Scale Precipitation Variability Over the Tropics: New Insights from Observations and Modelling explores the latest developments in the observation and modelling of tropical precipitation. Researchers will benefit from this detailed analysis of recent advancements in the field. The text first examines recent satellite and RADAR observations and how those breakthroughs enhance our understanding. This is followed by a review of NASA A-train observations as well as extreme events. The editors also look at predicting precipitation variability with a state-of-the-art ensemble forecast system. The text wraps with a discussion of multiscale cloud and precipitation variability with the backdrop of a changing climate. This text will provide researchers with new insights and a deeper understanding of the latest advances in the observation and modelling of tropical precipitation.