Böcker utgivna av Elsevier Science & Technology

Principles of Engineering Tribology: Fundamentals and Applications introduces readers to the core theories and fundamentals of the field, its basic terminology and concepts, as well as advanced topics such as the tribological properties of various engineering surfaces, roughness measurements, and the mechanics of surface contact. The fundamentals of friction and wear of metallic and non-metallic materials such as polymers, ceramics, rubbers, and composites are discussed, as are fluidic, gaseous, grease, and solid media lubrication techniques. In addition, the properties of lubricants and various types of additives incorporated are discussed, along with a methodology for conducting friction, wear and lubrication laboratory testing and an overview of simulation and modeling methods for various tribosystems. Case studies and applications are featured throughout, with a particular emphasis on analyzing failure modes of tribosystems.

Deprescribing and Polypharmacy in an Aging Population supports healthcare professionals across global healthcare institutions in reducing polypharmacy-related drug replated problems (DRPs) by working with patients, families, interprofessional healthcare professionals, and educational institutions to develop, implement, test, improve upon, and educate on strategies for deprescribing and optimizing patient safety. Polypharmacy, the use of multiple medications at the same time by one person, is very common in various patient populations, including those who lack primary physicians, patients with mental health conditions, patients with multiple chronic conditions, and in the aging population.

Distributed Computing to Blockchain: Architecture, Technology, and Applications provides researchers, computer scientists, and data scientists with a comprehensive and applied reference covering the evolution of distributed systems computing into blockchain and associated systems. Divided into three major sections, the book explores the basic topics in the blockchain space extending from distributed systems architecture, distributed ledger, decentralized web to introductory aspects of cryptoeconomics (cryptography and economics) of decentralized applications. The book further explores advanced concepts such as smart contracts; distributed token mining, initial coin offerings; proof of work; public, private, and other blockchains; cryptography; security; and blockchains. The book goes on to review byzantine fault tolerance, distributed ledgers versus blockchains, and blockchain protocols. The final section covers multiple use cases and applications of distributed computing and the future directions for blockchains.

Membrane Dehumidification and Cooling: Fundamentals and Applications presents the state-of-the-art on membrane dehumidifiers, highlighting their most recent advancements and providing key insights into global R&D interests. With a strong focus on applications, the book offers characterization techniques to evaluate the potential of hygroscopic materials, as well as experimental methods to study the dehumidifiers' performance. The book begins by highlighting the demerits of conventional cooling systems and then reviews electrically driven alternative cooling solutions. A comparative study between different dehumidification techniques is also given, along with sections on fundamental transport mechanisms and thermodynamic modeling. Finally, scaling, heat transfer and thermodynamic analysis are presented, along with a review of hybrid membrane-based air-conditioners. This book is a one-stop resource for recent advancements in membrane dehumidification and cooling applications. It is an essential read for students, researchers and engineers interested in thermal engineering, heat and mass transfer, alternative cooling, energy materials and dehumidification.

Advances in Nano and Biochemistry: Environmental and Biomedical Applications gives insights into this advanced interdisciplinary science that encompasses the principles of physics and physical chemistry for the investigation of various processes and problems in biological systems. The book is a concise culmination of biophysical chemistry knowledge acquired through core concepts and advanced technologies for addressing emerging challenges in environmental and biomedical applications. Sections cover early diagnostic techniques and accurate treatment strategies using bioinspired, sustainable technologies, including nanomaterials, nanoenzymes, biopolymers, electrochemical biomolecule sensors, biocompatible magnetic nanomaterials, quantum dots and hybrid structures, and DNA nanotechnology. Other sections discuss advanced technologies for sensing and remedying environmental pollutants, including but not limited to, photocatalytic oxidations, gum polysaccharides based nanostructured materials, bio-inspired and biocompatible nanomaterials, hydrogel nanocomposites, and contemporary enzymes and nanozymes based¿technologies. Ultimately, the state-of-the-art chapters in this book will empower researchers to combine two complementary elements - chemical analysis use and biomedical applications.

Handbook of Organizational Creativity: Individual and Group Level Influences, Second Edition covers creativity from many perspectives in two unique volumes, including artificial Intelligence work, creativity within specific applied domains (e.g., engineering, science, therapy), and coverage of leadership. The book includes individual, team and organizational level factors and includes organizational interventions to facilitate creativity (such as training). Chapters focus on creative abilities and creative problem-solving processes, along with individual differences such as motivation, affect and personality. New chapters include the neuroscience of creativity, creativity and meaning, morality/ethicality and creativity, and creative self-beliefs. Sections on group level phenomena examine team cognition, team social processes, team diversity, social networks, and multi-team systems and creativity. Final coverages includes different types and approaches to leadership, such as transformational leadership, ambidextrous leadership leader-follower relations, and more.

Diagnostic Molecular Biology, Second Edition describes the fundamentals of molecular biology in a clear, concise manner with each technique explained within its conceptual framework and current applications of clinical laboratory techniques comprehensively covered. This targeted approach covers the principles of molecular biology, including basic knowledge of nucleic acids, proteins and chromosomes; the basic techniques and instrumentations commonly used in the field of molecular biology, including detailed procedures and explanations; and the applications of the principles and techniques currently employed in the clinical laboratory. Topics such as whole exome sequencing, whole genome sequencing, RNA-seq, and ChIP-seq round out the discussion. Fully updated, this new edition adds recent advances in the detection of respiratory virus infections in humans, like influenza, RSV, hAdV, hRV but also corona. This book expands the discussion on NGS application and its role in future precision medicine.

CRISPR-Cas System in Translational Biotechnology discusses applied and translational aspects of the CRISPR-Cas technology. The book bridges the gap between theoretical knowledge and practical solutions surrounding this emerging and impactful technology in several academic and industrial fields. It is split in five sections: CRISP-Cas fundamentals and advancements; CRISP-Cas in medical biotechnology; CRISP-Cas in environmental biotechnology; CRISP-Cas in food biotechnology; and biosafety, patents and commercialization of CRISP-Cas technology. Written by experts from diverse backgrounds, the content covers the subject and its impact in multiple fields. It is a valuable resource for graduate students and researchers on bioinformatics, systems biology, and members of the biomedical field and biotechnology industry who are interested in learning more about CRISP-Cas system and its applications.

Novel Formulations and Future Trends, Volume Three in the Recent and Future Trends in Pharmaceutics series, explores aspects of pharmaceutics with an original approach focused on technology, novelties and future trends. It discusses the most important developments in drug delivery, including important and exciting areas such as mucosal, implantable, transdermal, gastroretentive, vaccine and targeted drug delivery systems. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. This is an essential reference for researchers in academia and industry as well as advanced graduate students.New technologies are also explored including 3D printing and computational pharmaceutics.

Fundamentals of Data Science: Theory and Practice presents basic and advanced concepts in data science along with real-life applications. The book provides students, researchers and professionals at different levels a good understanding of the concepts of data science, machine learning, data mining and analytics. Users will find the authors' research experiences and achievements in data science applications, along with in-depth discussions on topics that are essential for data science projects, including pre-processing, that is carried out before applying predictive and descriptive data analysis tasks and proximity measures for numeric, categorical and mixed-type data. The book's authors include a systematic presentation of many predictive and descriptive learning algorithms, including recent developments that have successfully handled large datasets with high accuracy. In addition, a number of descriptive learning tasks are included.

Hemostasis Management of the Pediatric Surgical Patient provides knowledge on the emerging area of pediatric hemostasis and its management. It discusses aspects of perioperative blood management in the pediatric population, including how to accurately estimate and monitor bleeding and determine optimal treatment regimens for bleeding in pediatric surgical patients. It also provides information on the implementation of intraoperative blood conservation strategies, goal-directed transfusion therapy, and postoperative estimation of bleeding and thrombotic risks. This book is a valuable resource to pediatric practitioners and researchers who need comprehensive information on pediatric hematology, from basic physiology to pre-, intra- and postoperative care of pediatric patients. The coagulation system of children evolves with age as evidenced by marked physiological differences in the concentration of hemostatic proteins between children of different age groups and adults. Consequently, there are distinct differences in hemostatic management between adult and pediatric patients.

Artificial Intelligence in Healthcare and COVID-19 showcases theoretical concepts and implementational and research perspectives surrounding AI. The book addresses both medical and technological visions, making it even more applied. With the advent of COVID-19, it is obvious that leading universities and medical schools must include these topics and case studies in their usual courses of health informatics to keep up with the pace of technological and medical advancements. This book will also serve professors teaching courses and industry practitioners and professionals working in the R&D team of leading medical and informatics companies who want to embrace AI and eHealth to fight COVID-19. Since AI in healthcare is a comparatively new field, there exists a vacuum of literature in this field, especially when applied to COVID-19. With the area of AI in COVID-19 being quite young, students and researchers usually face a struggle to rely on the few published papers (which are obviously too specific) or whitepapers by tech-giants (which are too wide).

Snow Leopards, Second Edition provides a foundational, comprehensive overview of the biology, ecology and conservation of this iconic species. This updated edition incorporates all the recent information from range-wide surveys and conservation projects, the results of technical and advances particularly in genetics, camera trapping and satellite tracking, and evaluates emerging threats. New chapters synthesize the novel scientific methods and statistical analyses used to develop density and population estimates and how they inform conservation and management estimates. Sections cover historical information, the main biogeographic patterns, evolutionary trends, conservational efforts, and cultural significance. Status and distribution are fully updated for all 12 countries where snow leopards occur. Other sections describe established and emerging threats, including human-wildlife conflict, illegal trade, infrastructure development, and climate change along with conservation solutions used to address these threats. The book concludes with a final section on global snow leopard initiatives and future potentials.

AI Computing Systems: An Application Driven Perspective adopts the principle of "application-driven, full-stack penetration" and uses the specific intelligent application of "image style migration" to provide students with a sound starting place to learn. This approach enables readers to obtain a full view of the AI computing system. A complete intelligent computing system involves many aspects such as processing chip, system structure, programming environment, software, etc., making it a difficult topic to master in a short time.

Microbiome and the Eye: What's the connection? highlights how alterations in the gut and eye microbiomes can lead to systemic immune alterations with subsequent effects on the eye. The book is divided into two sections, one highlighting how alterations in the gut microbiome impact various components of health outside the gut, with a focus on the immune system and inflammatory mediators, and the second focusing on studies on a variety of ocular diseases, including ocular surface diseases/dry eye, keratitis, uveitis, glaucoma, and retinopathy to gut dysbiosis. With its translational approach, the book is suitable for both researchers and clinicians. The book will help readers understand the mechanisms in which gut and eye microbiome composition may influence health in multiple compartments, with a focus on eye diseases.

Natural Plant Products in Inflammatory Bowel Diseases: Preventive and Therapeutic Potential organizes all evidence to understand which natural products are the first steps of investigation and which have strong evidence of their effects in inflammatory bowel diseases, have been tested in clinical trials, and have received approval to be officially used. In addition to providing information regarding the research with natural products in inflammatory bowel diseases, this reference will also highlight the molecular mechanisms behind the effects of natural products in inflammatory bowel diseases with the aid of figures, video animations and dynamic tables. Compiled from research group members from different parts of the world and specialized in inflammatory bowel diseases and related topics, this important reference will be useful to health professionals, researchers, professors, and industry managers as it provides helpful information on the subject, with the potential to inspire health care, relevant research and product innovation.

Glycoside Hydrolases provides a detailed overview of the biochemical, biophysical, and protein engineering properties of glycoside hydrolases, a class of enzymes in growing use across various applications. Here, more than a dozen global experts discuss the structural and catalytic mechanisms of specific glycoside hydrolases, followed by their implications in biotechnological applications of different industrial sectors such as the food and feed industry, paper and pulp industry, the bioenergy sector and the pharmaceutical industry. Authors consider how the application of glycoside hydrolases may boost industrial production of valued products, and the broader environmental and sustainability goals of converting agrowaste into valued products. This book helps researchers and students across industry and academia gain deep knowledge of glycoside hydrolases, to advance new experimental research and applications from biofuel to drug discovery.

Ureases: Foundations, Classes, and Applications provides a thorough, practical analysis of ureases-enzymes of growing relevance across a range of biotechnological applications and drug discovery. Unique in many aspects, ureases are one of the few enzymes to have nickel in their active sites. This book covers all aspects of this enzymatic class starting with foundational overview and then providing historical urease research and current state, from basic biochemistry to the use of ureases as hallmarks in enzymology, crystallography, and bioinorganic chemistry. The different classes of ureases, structurally diverse but chemically equivalent, are individually discussed.The multi-protein, multi-step activation of ureases (with chemical modification of residues, transport, and transfer of nickel ions) are examined in-depth, along with the catalytic mechanisms of ureolysis and its inhibitors. The final two sections of the book address multiple applications of ureases in health and biotechnology, respectively, going from gastric ulcer treatment to architectural uses in buildings and engineering. Future applications and next steps in research are also considered.

Building Energy Flexibility and Demand Management looks at the high penetration of intermittent renewable energy sources and the need for increased flexibility. Ensuring electrical power systems adapt to dynamic energy demand and supply conditions, the book supports the transition to a renewable energy future with current fluctuating power generation. By facilitating the penetration of renewable energy sources into the building sector and balancing electricity supply with demand in real-time, this book will provide fundamental concepts, theories, and methods to understand, quantify, design and optimize building energy flexibility. In addition, the book also provides case studies with emerging technologies to enhance building energy flexibility and demonstrate how demand management strategies can utilize energy flexibility for demand reduction and load shifting. It will be useful for all those researchers and engineers working in flexible energy systems and advanced demand side management strategies.

Phytopharmaceuticals and Herbal Drugs: Prospects and Safety Issues in the Delivery of Natural Products explores the delivery aspects of plant-based drugs, providing insights into formulation constraints associated with plant-based drugs, the development of novel delivery systems based on polymers or lipids, and how combining natural products with technological advancements in drug delivery is making large strides. Some of the best-selling drugs for the treatment of diseases like cancer, ulcers and malaria are either natural products or their derivatives, all of which are covered in this comprehensive resource. This book will be useful to researchers working in plant-derived medicines and the development of their delivery systems, including sections on their derivatives and analogs that represent over 50% of all drugs in clinical use. Active ingredients originated from plant resources generally exhibit compromised desired effects limited by issues such as stability, solubility, molecular size, bioavailability and toxicity.

Ethics for Health Promotion and Health Education discusses ethical principles and interpretations by classical ethicists as they apply to health promotion and health education. The book unpacks ethical expectations in promoting and teaching health in both the classroom and as a researcher or practitioner and then applies the code of ethics using case study methods throughout. This informative text was written by health educators and practitioners to assist health educator and practitioner communities.

Robotics for Cell Manipulation and Characterization provides fundamental principles underpinning robotic cell manipulation and characterization, state-of-the-art technical advances in micro/nano robotics, new discoveries of cell biology enabled by robotic systems, and their applications in clinical diagnosis and treatment. This book covers several areas, including robotics, control, computer vision, biomedical engineering and life sciences using understandable figures and tables to enhance readers' comprehension and pinpoint challenges and opportunities for biological and biomedical research.

Processing Technologies and Food Protein Digestion covers the effect of all the applied and emerging processing technologies, both thermal and non-thermal, on the digestion of food proteins derived from egg, milk, meat, plants, cereals, fish and seafood. Written by experts from a multidisciplinary perspective, each chapter addresses the effects of processing technologies, particularly emerging technologies such as pulsed electric field, ultrasound, high-pressure, pulsed light, and ohmic heating on the digestion of food proteins. This remarkable reference is the first compilation of available literature in the protein digestibility area.

Automata Theory and Formal Languages presents the difficult concepts of automata theory in a straightforward manner, including discussions on diverse concepts and tools that play major roles in developing computing machines, algorithms and code. Automata theory includes numerous concepts such as finite automata, regular grammar, formal languages, context free and context sensitive grammar, push down automata, Turing machine, and decidability, which constitute the backbone of computing machines. This book enables readers to gain sufficient knowledge and experience to construct and solve complex machines. Each chapter begins with key concepts followed by a number of important examples that demonstrate the solution. The book explains concepts and simultaneously helps readers develop an understanding of their application with real-world examples, including application of Context Free Grammars in programming languages and Artificial Intelligence, and cellular automata in biomedical problems.

In 2018, the International Committee on Taxonomy of Viruses (ICTV) approved significant changes leading to a comprehensive taxonomic scheme, allowing the global organization of the virus world (also known as virus megataxonomy). Aquaculture Virology, Second Edition updates the current knowledge on aquatic animal viruses so that all virus families (including those with many newly discovered aquatic animal viruses and those with previously unclassified aquatic animal viruses that have been now assigned) are available under one cover, increasing the number of book chapters from 37 in the first edition to 44 chapters in the second edition. The aims, philosophy, target audience, focus, and format of this second edition of Aquaculture Virology remain unchanged. Like the first edition, this book is a systematic and concise resource useful to anyone involved with or looking to move into aquaculture and fisheries. Clinical veterinarians, aquaculture disease practitioners, biologists, farmers, and all those in industry, government, or academia interested in aquatic animal virology will find this book extremely useful.

Navigating Non-coding RNA: From Biogenesis to Therapeutic Application provides a concise overview of the field of non-coding RNA (ncRNA). Chapters cover the history of discoveries that have occurred in the area of ncRNA, specific types of ncRNA, housekeeping ncRNAs such as ribosomal RNA, transfer RNA, small nuclear RNA and telomerase RNA, regulatory ncRNAs such as microRNA, small interfering RNA, long non-coding RNA and Y RNA. Biogenesis, structure, function, and regulation of each of these are also explored in addition to traditional and cutting-edge methods for the identification, functional characterization and structural characterization of ncRNA. The book also focuses on the different types of epitranscriptomic modifications and their involvement in regulating ncRNA structure, stability and intermolecular interactions in addition to the role of ncRNAs in a range of diseases and potential therapeutic applications.

The Physiology of Dolphins is a robust, up-to-date reference. It provides a collection of review chapters from leaders in the field of dolphin ecophysiology, making it essential for instructors, researchers, and graduate students interested in the physiological and anatomical adaptations that make life possible for these charismatic marine mammals. Showcasing recent technological developments, it covers the complete physiology of these marine mammals and includes information on the current threats for dolphins and whales from environmental pressures such as climate change, overfishing, pollution, and our increasing human presence in the ocean. This is an excellent reference providing easy-to-follow details of the latest available research methods and some of the newer technologies that are expanding the field of marine mammal physiology.

Vitamins and Minerals in Neurological Disorders offers readers a comprehensive reference addressing their relationship to brain health in a wide variety of neurological diseases. Examining various compounds, this broad coverage allows readers to learn about the role nutrient deficiency plays in the pathology of many conditions, as well as their potential in treatment. The book covers diseases including Alzheimer's, Parkinson's, ALS, and MS, along with severe neurological conditions like brain injury, stroke, headache and migraine. This volume provides a platform for research on vitamins, minerals and future investigations of these compounds.

Treatments, Nutraceuticals, Supplements and Herbal Medicine in Neurological Disorders offers readers a comprehensive reference on their potential for treatment in a wide variety of neurological diseases. Spanning various types of these compounds, this broad coverage allows readers to learn about the use of nutraceuticals and botanicals alone, or in combination with, other dietary regimes and/or vitamins and minerals. It covers diseases including Alzheimer's, Parkinson's, ALS and MS, and severe neurological conditions including brain injury, stroke, headache and migraine. This volume provides a platform for research on nutraceuticals and botanical agents and on future investigations of these compounds. There are over 600 neurological disorders affecting both the central and peripheral nervous systems, some of which have been treated by nutraceuticals and herbal medicine, hence this is a timely resource on the topics covered.