AI Computing Systems: An Application Driven Perspective adopts the principle of "application-driven, full-stack penetration" and uses the specific intelligent application of "image style migration" to provide students with a sound starting place to learn. This approach enables readers to obtain a full view of the AI computing system. A complete intelligent computing system involves many aspects such as processing chip, system structure, programming environment, software, etc., making it a difficult topic to master in a short time.
Microbiome and the Eye: What's the connection? highlights how alterations in the gut and eye microbiomes can lead to systemic immune alterations with subsequent effects on the eye. The book is divided into two sections, one highlighting how alterations in the gut microbiome impact various components of health outside the gut, with a focus on the immune system and inflammatory mediators, and the second focusing on studies on a variety of ocular diseases, including ocular surface diseases/dry eye, keratitis, uveitis, glaucoma, and retinopathy to gut dysbiosis. With its translational approach, the book is suitable for both researchers and clinicians. The book will help readers understand the mechanisms in which gut and eye microbiome composition may influence health in multiple compartments, with a focus on eye diseases.
Natural Plant Products in Inflammatory Bowel Diseases: Preventive and Therapeutic Potential organizes all evidence to understand which natural products are the first steps of investigation and which have strong evidence of their effects in inflammatory bowel diseases, have been tested in clinical trials, and have received approval to be officially used. In addition to providing information regarding the research with natural products in inflammatory bowel diseases, this reference will also highlight the molecular mechanisms behind the effects of natural products in inflammatory bowel diseases with the aid of figures, video animations and dynamic tables. Compiled from research group members from different parts of the world and specialized in inflammatory bowel diseases and related topics, this important reference will be useful to health professionals, researchers, professors, and industry managers as it provides helpful information on the subject, with the potential to inspire health care, relevant research and product innovation.
Glycoside Hydrolases provides a detailed overview of the biochemical, biophysical, and protein engineering properties of glycoside hydrolases, a class of enzymes in growing use across various applications. Here, more than a dozen global experts discuss the structural and catalytic mechanisms of specific glycoside hydrolases, followed by their implications in biotechnological applications of different industrial sectors such as the food and feed industry, paper and pulp industry, the bioenergy sector and the pharmaceutical industry. Authors consider how the application of glycoside hydrolases may boost industrial production of valued products, and the broader environmental and sustainability goals of converting agrowaste into valued products. This book helps researchers and students across industry and academia gain deep knowledge of glycoside hydrolases, to advance new experimental research and applications from biofuel to drug discovery.
Ureases: Foundations, Classes, and Applications provides a thorough, practical analysis of ureases-enzymes of growing relevance across a range of biotechnological applications and drug discovery. Unique in many aspects, ureases are one of the few enzymes to have nickel in their active sites. This book covers all aspects of this enzymatic class starting with foundational overview and then providing historical urease research and current state, from basic biochemistry to the use of ureases as hallmarks in enzymology, crystallography, and bioinorganic chemistry. The different classes of ureases, structurally diverse but chemically equivalent, are individually discussed.The multi-protein, multi-step activation of ureases (with chemical modification of residues, transport, and transfer of nickel ions) are examined in-depth, along with the catalytic mechanisms of ureolysis and its inhibitors. The final two sections of the book address multiple applications of ureases in health and biotechnology, respectively, going from gastric ulcer treatment to architectural uses in buildings and engineering. Future applications and next steps in research are also considered.
Building Energy Flexibility and Demand Management looks at the high penetration of intermittent renewable energy sources and the need for increased flexibility. Ensuring electrical power systems adapt to dynamic energy demand and supply conditions, the book supports the transition to a renewable energy future with current fluctuating power generation. By facilitating the penetration of renewable energy sources into the building sector and balancing electricity supply with demand in real-time, this book will provide fundamental concepts, theories, and methods to understand, quantify, design and optimize building energy flexibility. In addition, the book also provides case studies with emerging technologies to enhance building energy flexibility and demonstrate how demand management strategies can utilize energy flexibility for demand reduction and load shifting. It will be useful for all those researchers and engineers working in flexible energy systems and advanced demand side management strategies.
Phytopharmaceuticals and Herbal Drugs: Prospects and Safety Issues in the Delivery of Natural Products explores the delivery aspects of plant-based drugs, providing insights into formulation constraints associated with plant-based drugs, the development of novel delivery systems based on polymers or lipids, and how combining natural products with technological advancements in drug delivery is making large strides. Some of the best-selling drugs for the treatment of diseases like cancer, ulcers and malaria are either natural products or their derivatives, all of which are covered in this comprehensive resource. This book will be useful to researchers working in plant-derived medicines and the development of their delivery systems, including sections on their derivatives and analogs that represent over 50% of all drugs in clinical use. Active ingredients originated from plant resources generally exhibit compromised desired effects limited by issues such as stability, solubility, molecular size, bioavailability and toxicity.
Ethics for Health Promotion and Health Education discusses ethical principles and interpretations by classical ethicists as they apply to health promotion and health education. The book unpacks ethical expectations in promoting and teaching health in both the classroom and as a researcher or practitioner and then applies the code of ethics using case study methods throughout. This informative text was written by health educators and practitioners to assist health educator and practitioner communities.
Robotics for Cell Manipulation and Characterization provides fundamental principles underpinning robotic cell manipulation and characterization, state-of-the-art technical advances in micro/nano robotics, new discoveries of cell biology enabled by robotic systems, and their applications in clinical diagnosis and treatment. This book covers several areas, including robotics, control, computer vision, biomedical engineering and life sciences using understandable figures and tables to enhance readers' comprehension and pinpoint challenges and opportunities for biological and biomedical research.
Processing Technologies and Food Protein Digestion covers the effect of all the applied and emerging processing technologies, both thermal and non-thermal, on the digestion of food proteins derived from egg, milk, meat, plants, cereals, fish and seafood. Written by experts from a multidisciplinary perspective, each chapter addresses the effects of processing technologies, particularly emerging technologies such as pulsed electric field, ultrasound, high-pressure, pulsed light, and ohmic heating on the digestion of food proteins. This remarkable reference is the first compilation of available literature in the protein digestibility area.
Automata Theory and Formal Languages presents the difficult concepts of automata theory in a straightforward manner, including discussions on diverse concepts and tools that play major roles in developing computing machines, algorithms and code. Automata theory includes numerous concepts such as finite automata, regular grammar, formal languages, context free and context sensitive grammar, push down automata, Turing machine, and decidability, which constitute the backbone of computing machines. This book enables readers to gain sufficient knowledge and experience to construct and solve complex machines. Each chapter begins with key concepts followed by a number of important examples that demonstrate the solution. The book explains concepts and simultaneously helps readers develop an understanding of their application with real-world examples, including application of Context Free Grammars in programming languages and Artificial Intelligence, and cellular automata in biomedical problems.
In 2018, the International Committee on Taxonomy of Viruses (ICTV) approved significant changes leading to a comprehensive taxonomic scheme, allowing the global organization of the virus world (also known as virus megataxonomy). Aquaculture Virology, Second Edition updates the current knowledge on aquatic animal viruses so that all virus families (including those with many newly discovered aquatic animal viruses and those with previously unclassified aquatic animal viruses that have been now assigned) are available under one cover, increasing the number of book chapters from 37 in the first edition to 44 chapters in the second edition. The aims, philosophy, target audience, focus, and format of this second edition of Aquaculture Virology remain unchanged. Like the first edition, this book is a systematic and concise resource useful to anyone involved with or looking to move into aquaculture and fisheries. Clinical veterinarians, aquaculture disease practitioners, biologists, farmers, and all those in industry, government, or academia interested in aquatic animal virology will find this book extremely useful.
Navigating Non-coding RNA: From Biogenesis to Therapeutic Application provides a concise overview of the field of non-coding RNA (ncRNA). Chapters cover the history of discoveries that have occurred in the area of ncRNA, specific types of ncRNA, housekeeping ncRNAs such as ribosomal RNA, transfer RNA, small nuclear RNA and telomerase RNA, regulatory ncRNAs such as microRNA, small interfering RNA, long non-coding RNA and Y RNA. Biogenesis, structure, function, and regulation of each of these are also explored in addition to traditional and cutting-edge methods for the identification, functional characterization and structural characterization of ncRNA. The book also focuses on the different types of epitranscriptomic modifications and their involvement in regulating ncRNA structure, stability and intermolecular interactions in addition to the role of ncRNAs in a range of diseases and potential therapeutic applications.
The Physiology of Dolphins is a robust, up-to-date reference. It provides a collection of review chapters from leaders in the field of dolphin ecophysiology, making it essential for instructors, researchers, and graduate students interested in the physiological and anatomical adaptations that make life possible for these charismatic marine mammals. Showcasing recent technological developments, it covers the complete physiology of these marine mammals and includes information on the current threats for dolphins and whales from environmental pressures such as climate change, overfishing, pollution, and our increasing human presence in the ocean. This is an excellent reference providing easy-to-follow details of the latest available research methods and some of the newer technologies that are expanding the field of marine mammal physiology.
Vitamins and Minerals in Neurological Disorders offers readers a comprehensive reference addressing their relationship to brain health in a wide variety of neurological diseases. Examining various compounds, this broad coverage allows readers to learn about the role nutrient deficiency plays in the pathology of many conditions, as well as their potential in treatment. The book covers diseases including Alzheimer's, Parkinson's, ALS, and MS, along with severe neurological conditions like brain injury, stroke, headache and migraine. This volume provides a platform for research on vitamins, minerals and future investigations of these compounds.
Treatments, Nutraceuticals, Supplements and Herbal Medicine in Neurological Disorders offers readers a comprehensive reference on their potential for treatment in a wide variety of neurological diseases. Spanning various types of these compounds, this broad coverage allows readers to learn about the use of nutraceuticals and botanicals alone, or in combination with, other dietary regimes and/or vitamins and minerals. It covers diseases including Alzheimer's, Parkinson's, ALS and MS, and severe neurological conditions including brain injury, stroke, headache and migraine. This volume provides a platform for research on nutraceuticals and botanical agents and on future investigations of these compounds. There are over 600 neurological disorders affecting both the central and peripheral nervous systems, some of which have been treated by nutraceuticals and herbal medicine, hence this is a timely resource on the topics covered.
Diet and Nutrition in Neurological Disorders offers readers a comprehensive reference on the effect of dietary regimes in a wide variety of neurological diseases. With coverage of different types of diets, including Mediterranean or DASH, this broad coverage allows readers to learn about diets and their affect on specific disorders which may well be relevant to other conditions. This includes diseases such as Alzheimer's, Parkinson's, ALS, MS and severe neurological conditions such as brain injury, stroke, headache and migraine. This volume provides a platform for research on new dietary regimes and on future investigations of diet and nutrition.
Computational Modeling of Infectious Disease: With Applications in Python provides an illustrated compendium of tools and tactics for analyzing infectious diseases using cutting-edge computational methods. From simple S(E)IR models, and through time series analysis and geospatial models, this book is both a guided tour through the computational analysis of infectious diseases and a quick-reference manual. Chapters are accompanied by extensive practical examples in Python, illustrating applications from start to finish. This book is designed for researchers and practicing infectious disease forecasters, modelers, data scientists, and those who wish to learn more about analysis of infectious disease processes in the real world.--
The World of Sea Cucumbers: Challenges, Advances, and Innovations provides broad coverage of sea cucumber biology, ecology, fisheries, aquaculture, and trade while also bringing forward novel cultural, socioeconomic and scientific topics related to commercial and non-commercial species worldwide. Written by international experts in their respective fields, the book offers a unique outlook into the fascinating world of sea cucumbers while also providing valuable information to various stakeholders and researchers. Commercial fisheries and aquaculture programs are addressed, especially as they relate to emerging species, but the book also covers novel, understudied or lesser-known biological, ecological, and commercial aspects. The involvement of Indigenous peoples and minorities in various community-level initiatives and on the cultural significance/impact of sea cucumbers in many regions are also examined. Finally, breakthroughs and emerging biotechnologies centered on sea cucumbers are presented.
Epigenetic Cancer Therapy, Second Edition provides a comprehensive discussion of healthy and aberrant epigenetic biology, along with new discoveries to improve our understanding of cancer epigenetics and therapeutics. The book encompasses large-scale intergovernmental initiatives, as well as recent findings across cancer stem cells, rational drug design, clinical trials, and chemopreventative strategies. As a whole, the work articulates and raises the profile of epigenetics as a therapeutic option in the future management of cancer. Since the publication of the first edition of this book, the field of epigenetics has undergone significant change. New epigenetic therapies have been designed and approved for clinical use. Our knowledge of the plasticity of the epigenome in cancer and disease has expanded dramatically, with increasing evidence linking pollution to epigenetic changes in cancer development. This second edition has been fully updated to address these changes, along with promising therapeutic programs such as CRISPR/Cas9 mediated approaches, CAR-T based therapies, epigenetic priming, histone modifications, and similar, transformative advances across synthetic biology and cellular engineering.
Plant Small RNA for Food Crops provides foundational insights into the role of small RNA in food crops in varying environmental conditions and how it can help in developing molecular frameworks to support agricultural sustainability to feed the world¿s population. Small RNA populations have been widely identified in various plants and have been reported to be involved in regulating the molecular functioning of plants and their responses for biotic and abiotic environmental factors. Until now, however, a detailed compilation of role of small RNAs in food crops growth, yield and environmental responses had been unavailable. This book provides a detailed description of role of various small RNAs whose utilization in a range of food crops may serve to improve sustainability, productivity, and maintenance during environmental stress conditions. It brings together the reported small RNAs along with their applications specific to food crops, but also covers recent studies, innovations and future perspectives.
"A Mathematical Approach to Special Relativity introduces the mathematical formalisms of special and general relativity. Developed from the author's experience teaching physics to students across all levels, the valuable resource introduces key concepts, building in complexity and using increasingly advanced mathematical tools as it progresses. Without assuming a background in calculus, the text begins with symmetry, before delving more deeply into Galilean relativity. Throughout, the book provides examples and useful 'Guides to the Literature.' This unique text emphasizes the experimental consequences and verifications of the underpinning theory in order to provide students with a solid foundation in this key area."
Dysphagia: Diagnosis and Treatment of Esophageal Motility Disorders provides a interdisciplinary overview of the diagnosis and management of dysphagia and other esophageal symptoms. All aspects of dysphagia are covered, with detailed consideration of both physiology and evaluation methods. Hot topics include coverage on the pharmacological causes of dysphagia, the physiology of normal swallowing, ambulatory pH monitoring as well as recurrent dysphagia after treatments. The content is grounded in evidence-based medicine that is the result of clinical outcome research, both prospective and randomized, making this the perfect reference for clinical researchers and a go-to for general surgeons, foreguts surgeons, thoracic surgeons and gastroenterologists.
Comparative Mammalian Immunology: The Evolution and Diversity of the Immune Systems of Mammals provides a review on the current knowledge of mammalian immune systems from a comparative viewpoint. This reference encompasses recent work on the immune systems of marine mammals, bats and marsupials in addition to other lesser-known species, with the immune systems of humans and laboratory mice as components of chapters on primates and rodents respectively. The book also makes use of the most recent studies on the genomic sequences of the mammals to identify both common and unique features of each mammal's immune system. The book elucidates the complex, but coordinated and controlled series of interactions involving cells and molecules that has evolved to protect the host against disease. Mammals consist of a highly diverse group of animals in which the immune system has been subjected to a variety of selective pressures. This is reflected in differences in the organization and function of their immune systems, and is especially seen in those gene families characterized by complexity and polymorphism.
The Veterinarian's Guide to Animal Welfare provides an overview of various aspects of animal welfare that are particularly relative to the veterinary profession. The book explores various ways of viewing and assessing welfare, as well as the numerous factors that influence perceptions. Emphasis is placed on contemporary issues across, and within, major species groups. The book's authors are internationally known experts in the veterinary aspects of animal welfare and have written numerous articles on animal welfare, behavior, euthanasia and the human-animal bond. This book is written for the veterinary profession and was designed to be used as a textbook for animal welfare courses at colleges and schools of veterinary medicine. It complements the Model Curriculum for the Study of Animal Welfare (AVMA 2015) and its attendant course syllabus. This is an important resource for graduate veterinarians seeking to improve their understanding of the numerous aspects of animal welfare.
This second edition of Applied Behavior Analysis Advanced Guidebook: A Manual for Professional Practice gives behavior analysts and other behavioral practitioners pragmatic advice, direction, and recommendations for being an effective clinician, consultant, supervisor, and performance manager. Like the first edition, the book includes chapters on evidence-based practice competencies as well as many new areas devoted to professional development, technology, and telehealth service delivery. Written by expert scientist-practitioners, each chapter is filled with guidance that follows from the most contemporary research support.
Renewable Energy - Volume 1: Solar, Wind, and Hydropower: Definitions, Developments, Applications, Case Studies, and Modelling and Simulation is a comprehensive resource for those wanting an authoritative volume on the significant aspects of these rapidly growing renewable technologies. Providing a structured approach to the emerging technologies and advances in the implementation of solar, wind and hydro energy, the book offers the most requested and desirable practical elements for the renewable industry. Sections cover definitions, applications, modeling and analysis through case study and example. This coordinated approach allows for standalone, accessible, and functioning chapters dedicated to a particular energy source, giving researchers and engineers an important and unique consolidated source of information on all aspects of these state-of-the-art fields.
Real-Time Simulation Technology for Modern Power Electronics provides an invaluable foundation and state-of-the-art review on the most advanced implementations of real-time simulation as it appears poised to revolutionize the modeling of power electronics. The book opens with a discussion of power electronics device physic modeling, component modeling, and power converter modeling before addressing numerical methods to solve converter model, emphasizing speed and accuracy. It discusses both CPU-based and FPGA-based real-time implementations and provides an extensive review of current applications, including hardware-in-the-loop and its case studies in the micro-grid and electric vehicle applications. The book closes with a review of the near and long-term outlooks for the evolving technology. Collectively, the work provides a systematic resource for students, researchers, and engineers in the electrical engineering and other closely related fields.
Ductility and Formability of Metals: A Metallurgical Engineering Perspective uses metallurgical, mechanical and physical principles and concepts to explain ductility while emphasizing the influence of material microstructure on damage mechanisms. Focusing on steel, aluminum, copper, titanium and magnesium alloys, the book examines the strain hardening behaviors of these metals and alloys, the influence of strain rate and temperature, and ductile fracture mechanics. Hot plastic deformation is covered with special consideration given to its interplay with recrystallization phenomena. Other phenomena such as Dynamic Strain Ageing (DSA) and Adiabatic Shear Banding (ASB) are discussed, and metal working applications such as forging, extrusion and machining are included throughout. Methods for control of ductile cracks in metal parts resulting from rolling, forging, extrusion, drawing, and sheet metal forming are also outlined.
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