Böcker utgivna av Elsevier Science & Technology

Heat exchangers, being fundamental components of energy and process systems, are both savers and spenders of energy. This work presents the ideas and industrial concepts in compact heat exchanger technology.

Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy addresses from a comprehensive and multidisciplinary approach the translational aspects and clinical perspectives of nano-pharmacokinetics using cancer as a model disease. Nano-pharmacokinetics is emerging as an important sub discipline of nanoscience and medical sciences because of the increasing safety issues of nanosystems on living organisms. This book reports the dynamics of nanosystems in living organisms for better understanding of nanotoxicity, pharmacology, biochemistry, physiology and medicine perspectives. It further examines current progress of state-of-the art pharmacokinetics mechanisms, which will be of great help to develop more clinical-oriented nanosystems with a wide safety margin. The book is divided into three sections: the first section focuses on the concept of pharmacokinetics with state-of-the-art Nano-Pharmacokinetics (NPK). The second section looks at the engineering of nanoparticles and pharmacokinetics clinical development. The final section focuses on Nano-Pharmacokinetics and Theranostics, elaborating the basic question of how pharmacokinetics of nanomaterials relate to their end applications such as cancer therapy. Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy will be useful to researchers in the field of nanoparticle based targeted drug delivery including pharmaceutical scientists, material scientists, chemists, nanotechnologists, biomedical scientists, and clinicians.

Suitable for career oriented security officers in both the private and public sectors, this title offers instructors and students all learning aids, designed to reflect the trends in this industry and to support and reinforce continued professional development.

Mitochondrial Dysfunction and Nanotherapeutics: Aging, Diseases, and Nanotechnology-Related Strategies in Mitochondrial Medicine provides a comprehensive overview of mitochondrial dysfunction and current strategies for targeting the organelle. Based on the most current research, the editor lined up a team of worldwide experts to cover the most exciting research in the area, considering the impact through the human life span. This book is structured in two parts that provide a good balance of foundational and applied content. Part I deals with an overview of mitochondrial dysfunction and its role in the aging process, including metabolic diseases, neuro-affective and neurodegenerative disorders, sepsis, and toxicological aspects. Part II covers therapeutic substance delivery to mitochondria with a focus on cancer, neurodegenerative diseases, and increasing the bioavailability of natural compounds of interest. Several nanoscale strategies are described. Mitochondrial Dysfunction and Nanotherapeutics: Aging, Diseases, and Nanotechnology-Related Strategies in Mitochondrial Medicine is a complete resource for researchers in this exciting field. Its comprehensive coverage makes this book particularly interesting to bioscience researchers looking to understand the foundations of mitochondrial health throughout the human life span. Additionally, clinician researchers, medical doctors, nutritionists, pharmacologists, and sports scientists may be attracted to the detailed information on the organelle-targeted delivery strategies.

Addresses unfamiliar feeds and provides a reference on the background, process technology and downstream applications required to help refineries maximize profits turning low-value feedstock to beneficial syngas and other fuel products.

Covers the main studies of nanoparticle production, reactions, and compounds, and reviews the work of leading scientists from around the world. This book provides the fundamentals and theory of nanoscience, and includes topics: synthesis and stabilization of nanoparticles, cryochemistry of metal atoms and nanoparticles, and chemical nanoreactors.

Helps you to understand different types of electronic circuits, how they work, and how they fit together to create modern electronic equipment, enabling you to apply, use, select, operate and discuss common electronic products and systems. This title helps you to learn about basic components of electronics such as resistors, capacitors and more.

Teaches readers the basics of performing the tests and measurements used in radio-frequency systems installation, proof of performance, maintenance, and troubleshooting. This work examines the instruments used in the various types of measurement before moving on to specific measurement methods.

Suitable for security officers and guards, this book offers the practical information, training, and need-to-know techniques for the realization of professional goals. It emphasizes proper skills required to improve job performance - customer service, security methods, patrolling, communicating, and report writing.

Presents a step-by-step design framework for a wide variety of power supplies. This book allows the reader to design linear, switching, and quasi-resonant switching power supplies. It describes such topics as magnetics, feedback loop compensation design, and EMI/RFI control.

Microsoft Outlook is the most widely used email program, and it offers the most programmability. This book covers both Outlook 2000 and Outlook 2002, and introduces key concepts for programming both Outlook forms for storing and exchanging data and Visual Basic for Applications modules that add new features to Outlook.

Reprogramming the Genome: CRISPR-Cas-based Human Disease Therapy, presents the collation of chapters written by eminent scientists worldwide. CRISPR-Cas9 is a key technology for targeted genome editing and regulation in a number of organisms including mammalian cells. It is a rapid, simple, and cost-effective solution. CRISPR-Cas system has recently gained much scientific and public attention. This volume covers CRISPR-Cas9 based mammalian genome editing, creating disease models, cancer therapy, neurological, heredity, blood disorders, defective gene correction, stem cells therapy, epigenetic modifications, patents, ethics, biosafety and regulatory issues challenges and opportunities. This book is a key source of information on mammalian genome editing available in a single volume. This book will be useful for beginners in mammalian genome editing and also students, researchers, scientists, policymakers, clinicians and stakeholders interested in genome editing in several areas.Offers basic understanding and a clear picture of mammalian genome editing through CRISPR-Cas systemsDiscusses how to create mammalian disease models, stem cell modification, epigenetic modifications, correction of defective gene in blood disorders, heredity, neurological disorders and many moreDiscusses the application of CRISPR-Cas9 systems in basic sciences, biomedicine, molecular biology, translational sciences, neurobiology, neurology, cancer, stem cells, and many more

Dust explosions are common and costly in a wide array of industries. It is imperative that knowledge of the origin, development, prevention and mitigation of dust explosions is imparted to the responsible safety manager. This book offers an evaluation of prevalent activities, testing methods, design measures and safe operating techniques.

Roselle: Production, Processing, Products and Biocomposites complies the latest findings on the production, processing, products and composites of the roselle plant. The book provides researchers with the latest information on its entire use, including fibers and fruit for any application. Subjects covered include environmental advantages and challenges, the plant as a renewable resource, economic issues such as the impact of biobased medicines, biodiesel, the current market for roselle products and regulations for food packaging materials. Sections include commentary from leading industrial and academic experts in the field who present cutting-edge research on roselle fiber for a variety of industries. By comprehensively covering the development and characterization of roselle fiber as a potential to replace conventional fiber made from petroleum-based polymers, this book is a must-have resource for anyone requiring up-to-date knowledge on the lifecycle of the roselle plant.

Translational Bioinformatics in Healthcare and Medicine offers an overview of main principles of bioinformatics, biological databases, clinical informatics, health informatics, viroinformatics and real-case applications of translational bioinformatics in healthcare. Written by experts from both technology and clinical sides, the content brings together essential knowledge to make the best of recent advancements of the field. The book discusses topics such as next generation sequence analysis, genomics in clinical care, IoT applications, blockchain technology, patient centered interoperability of EHR, health data mining, and translational bioinformatics methods for drug discovery and drug repurposing. In addition, it discusses the role of bioinformatics in cancer research and viroinformatics approaches to counter viral diseases through informatics. This is a valuable resource for bioinformaticians, clinicians, healthcare professionals, graduate students and several members of biomedical field who are interested in learning more about how bioinformatics can impact in their research and practice.

After more than 30 years, The Book of Fructans represents the first and most comprehensive coverage of fructans generated by pioneer glycoscientists from the field. It outlines the fundamentals of all fructan types, their terminology, chemical and structural-functional features, biosynthetic enzymes that make and break them, their presence and possible roles in nature, their evolutionary aspects and their microbial, enzymatic, and plant-based production. Additional sections cover the applications of fructans, specifically, the agro/chemical and biomedical applications, health, pharmaceutical and cosmetic applications, fructans in food and feed, fructan nanotechnology, the immunomodulatory and antiviral effects of fructans and the perspectives for fructans in circular economies and sustainable societies. Intended for scientists, entrepreneurs, academicians and students working in related fields, this book will be a useful resource for all who wish to learn more about these extraordinary carbohydrates.

Provides information on basic and applied aspects of biofuels production from algae. This book covers topics such as metabolic engineering and molecular biology for algae for fuel production, life cycle assessment and scale-up and commercialization.

Epigenetics and Metabolomics, a new volume in the Translational Epigenetics series, offers a synthesized discussion of epigenetic control of metabolic activity, and systems-based approaches for better understanding these mechanisms. Over a dozen chapter authors provide an overview of epigenetics in translational medicine and metabolomics techniques, followed by analyses of epigenetic and metabolomic linkage mechanisms likely to result in effective identification of disease biomarkers, as well as new therapies targeting the removal of the inappropriate epigenetic alterations. Epigenetic interventions in cancer, brain damage, and neuroendocrine disease, among other disorders, are discussed in-depth, with an emphasis on exploring next steps for clinical translation and personalized healthcare.