Böcker utgivna av Elsevier Science & Technology

Vitamins and Minerals in Neurological Disorders offers readers a comprehensive reference addressing their relationship to brain health in a wide variety of neurological diseases. Examining various compounds, this broad coverage allows readers to learn about the role nutrient deficiency plays in the pathology of many conditions, as well as their potential in treatment. The book covers diseases including Alzheimer's, Parkinson's, ALS, and MS, along with severe neurological conditions like brain injury, stroke, headache and migraine. This volume provides a platform for research on vitamins, minerals and future investigations of these compounds.

Treatments, Nutraceuticals, Supplements and Herbal Medicine in Neurological Disorders offers readers a comprehensive reference on their potential for treatment in a wide variety of neurological diseases. Spanning various types of these compounds, this broad coverage allows readers to learn about the use of nutraceuticals and botanicals alone, or in combination with, other dietary regimes and/or vitamins and minerals. It covers diseases including Alzheimer's, Parkinson's, ALS and MS, and severe neurological conditions including brain injury, stroke, headache and migraine. This volume provides a platform for research on nutraceuticals and botanical agents and on future investigations of these compounds. There are over 600 neurological disorders affecting both the central and peripheral nervous systems, some of which have been treated by nutraceuticals and herbal medicine, hence this is a timely resource on the topics covered.

Diet and Nutrition in Neurological Disorders offers readers a comprehensive reference on the effect of dietary regimes in a wide variety of neurological diseases. With coverage of different types of diets, including Mediterranean or DASH, this broad coverage allows readers to learn about diets and their affect on specific disorders which may well be relevant to other conditions. This includes diseases such as Alzheimer's, Parkinson's, ALS, MS and severe neurological conditions such as brain injury, stroke, headache and migraine. This volume provides a platform for research on new dietary regimes and on future investigations of diet and nutrition.

Computational Modeling of Infectious Disease: With Applications in Python provides an illustrated compendium of tools and tactics for analyzing infectious diseases using cutting-edge computational methods. From simple S(E)IR models, and through time series analysis and geospatial models, this book is both a guided tour through the computational analysis of infectious diseases and a quick-reference manual. Chapters are accompanied by extensive practical examples in Python, illustrating applications from start to finish. This book is designed for researchers and practicing infectious disease forecasters, modelers, data scientists, and those who wish to learn more about analysis of infectious disease processes in the real world.--

The World of Sea Cucumbers: Challenges, Advances, and Innovations provides broad coverage of sea cucumber biology, ecology, fisheries, aquaculture, and trade while also bringing forward novel cultural, socioeconomic and scientific topics related to commercial and non-commercial species worldwide. Written by international experts in their respective fields, the book offers a unique outlook into the fascinating world of sea cucumbers while also providing valuable information to various stakeholders and researchers. Commercial fisheries and aquaculture programs are addressed, especially as they relate to emerging species, but the book also covers novel, understudied or lesser-known biological, ecological, and commercial aspects. The involvement of Indigenous peoples and minorities in various community-level initiatives and on the cultural significance/impact of sea cucumbers in many regions are also examined. Finally, breakthroughs and emerging biotechnologies centered on sea cucumbers are presented.

Epigenetic Cancer Therapy, Second Edition provides a comprehensive discussion of healthy and aberrant epigenetic biology, along with new discoveries to improve our understanding of cancer epigenetics and therapeutics. The book encompasses large-scale intergovernmental initiatives, as well as recent findings across cancer stem cells, rational drug design, clinical trials, and chemopreventative strategies. As a whole, the work articulates and raises the profile of epigenetics as a therapeutic option in the future management of cancer. Since the publication of the first edition of this book, the field of epigenetics has undergone significant change. New epigenetic therapies have been designed and approved for clinical use. Our knowledge of the plasticity of the epigenome in cancer and disease has expanded dramatically, with increasing evidence linking pollution to epigenetic changes in cancer development. This second edition has been fully updated to address these changes, along with promising therapeutic programs such as CRISPR/Cas9 mediated approaches, CAR-T based therapies, epigenetic priming, histone modifications, and similar, transformative advances across synthetic biology and cellular engineering.

Plant Small RNA for Food Crops provides foundational insights into the role of small RNA in food crops in varying environmental conditions and how it can help in developing molecular frameworks to support agricultural sustainability to feed the world¿s population. Small RNA populations have been widely identified in various plants and have been reported to be involved in regulating the molecular functioning of plants and their responses for biotic and abiotic environmental factors. Until now, however, a detailed compilation of role of small RNAs in food crops growth, yield and environmental responses had been unavailable. This book provides a detailed description of role of various small RNAs whose utilization in a range of food crops may serve to improve sustainability, productivity, and maintenance during environmental stress conditions. It brings together the reported small RNAs along with their applications specific to food crops, but also covers recent studies, innovations and future perspectives.

"A Mathematical Approach to Special Relativity introduces the mathematical formalisms of special and general relativity. Developed from the author's experience teaching physics to students across all levels, the valuable resource introduces key concepts, building in complexity and using increasingly advanced mathematical tools as it progresses. Without assuming a background in calculus, the text begins with symmetry, before delving more deeply into Galilean relativity. Throughout, the book provides examples and useful 'Guides to the Literature.' This unique text emphasizes the experimental consequences and verifications of the underpinning theory in order to provide students with a solid foundation in this key area."

Comparative Mammalian Immunology: The Evolution and Diversity of the Immune Systems of Mammals provides a review on the current knowledge of mammalian immune systems from a comparative viewpoint. This reference encompasses recent work on the immune systems of marine mammals, bats and marsupials in addition to other lesser-known species, with the immune systems of humans and laboratory mice as components of chapters on primates and rodents respectively. The book also makes use of the most recent studies on the genomic sequences of the mammals to identify both common and unique features of each mammal's immune system. The book elucidates the complex, but coordinated and controlled series of interactions involving cells and molecules that has evolved to protect the host against disease. Mammals consist of a highly diverse group of animals in which the immune system has been subjected to a variety of selective pressures. This is reflected in differences in the organization and function of their immune systems, and is especially seen in those gene families characterized by complexity and polymorphism.

The Veterinarian's Guide to Animal Welfare provides an overview of various aspects of animal welfare that are particularly relative to the veterinary profession. The book explores various ways of viewing and assessing welfare, as well as the numerous factors that influence perceptions. Emphasis is placed on contemporary issues across, and within, major species groups. The book's authors are internationally known experts in the veterinary aspects of animal welfare and have written numerous articles on animal welfare, behavior, euthanasia and the human-animal bond. This book is written for the veterinary profession and was designed to be used as a textbook for animal welfare courses at colleges and schools of veterinary medicine. It complements the Model Curriculum for the Study of Animal Welfare (AVMA 2015) and its attendant course syllabus. This is an important resource for graduate veterinarians seeking to improve their understanding of the numerous aspects of animal welfare.

This second edition of Applied Behavior Analysis Advanced Guidebook: A Manual for Professional Practice gives behavior analysts and other behavioral practitioners pragmatic advice, direction, and recommendations for being an effective clinician, consultant, supervisor, and performance manager. Like the first edition, the book includes chapters on evidence-based practice competencies as well as many new areas devoted to professional development, technology, and telehealth service delivery. Written by expert scientist-practitioners, each chapter is filled with guidance that follows from the most contemporary research support.

Renewable Energy - Volume 1: Solar, Wind, and Hydropower: Definitions, Developments, Applications, Case Studies, and Modelling and Simulation is a comprehensive resource for those wanting an authoritative volume on the significant aspects of these rapidly growing renewable technologies. Providing a structured approach to the emerging technologies and advances in the implementation of solar, wind and hydro energy, the book offers the most requested and desirable practical elements for the renewable industry. Sections cover definitions, applications, modeling and analysis through case study and example. This coordinated approach allows for standalone, accessible, and functioning chapters dedicated to a particular energy source, giving researchers and engineers an important and unique consolidated source of information on all aspects of these state-of-the-art fields.

Real-Time Simulation Technology for Modern Power Electronics provides an invaluable foundation and state-of-the-art review on the most advanced implementations of real-time simulation as it appears poised to revolutionize the modeling of power electronics. The book opens with a discussion of power electronics device physic modeling, component modeling, and power converter modeling before addressing numerical methods to solve converter model, emphasizing speed and accuracy. It discusses both CPU-based and FPGA-based real-time implementations and provides an extensive review of current applications, including hardware-in-the-loop and its case studies in the micro-grid and electric vehicle applications. The book closes with a review of the near and long-term outlooks for the evolving technology. Collectively, the work provides a systematic resource for students, researchers, and engineers in the electrical engineering and other closely related fields.

Ductility and Formability of Metals: A Metallurgical Engineering Perspective uses metallurgical, mechanical and physical principles and concepts to explain ductility while emphasizing the influence of material microstructure on damage mechanisms. Focusing on steel, aluminum, copper, titanium and magnesium alloys, the book examines the strain hardening behaviors of these metals and alloys, the influence of strain rate and temperature, and ductile fracture mechanics. Hot plastic deformation is covered with special consideration given to its interplay with recrystallization phenomena. Other phenomena such as Dynamic Strain Ageing (DSA) and Adiabatic Shear Banding (ASB) are discussed, and metal working applications such as forging, extrusion and machining are included throughout. Methods for control of ductile cracks in metal parts resulting from rolling, forging, extrusion, drawing, and sheet metal forming are also outlined.

Processing of Food Products and Wastes With High Voltage Electrical Discharges presents basic knowledge on HVED technology, focusing on the mechanisms, related phenomena and effects, equipment design, methods and examples of application. Divided in three parts, the book covers the advantages and restrictions of HVED technology for the treatment of numerous specific food products, by-products and wastes, such as grape, oilseed, citrus by-products and wastes, lignocellulosic and algal biomass, meat and bacterias. This book act as a comprehensive resource for researchers to be able to use the data for the dimensioning of HVED and processing equipment and finding the optimal treatment parameters.

Falciparum Malaria: Diagnostic Tools, Therapeutic Advances, and Future Opportunities discusses the current state of therapeutic options for malaria, antimalarial drugs and drug targets. The book also covers recent progress in the development of vaccines and other approaches for malaria treatment, prevention and control and explores diagnostic tools and biomarkers. Sections examine potential biomarkers and their applications, molecular diagnostic tools, multi-omic approaches for the characterization of therapeutic action of potential new antimalarials, therapeutic advances in falciparum malaria, antimalarial drugs, targeting parasite apicoplast for antimalarial drug discovery, cellular and adjunctive therapies for malaria treatment, and future opportunities. With contributions from experts in the field, this book is an ideal resource for academics, researchers, graduates and industry engaged in malaria research, its diagnosis, and treatment.

Athlete's Heart: A Multimodal Approach - From Physiological to Pathological Cardiac Adaptations provides a complete overview of all adaptations of the heart to sport practice by highlighting the different diagnosis between athlete's heart and pathological remodeling. Written by international experts in the field, chapters discuss ECG findings, echocardiogram data, cardiac magnetic resonance and new forms of multimodality imaging, providing readers with evidence-based guidance on how to differentiate athlete's heart from cardiomyopathies. Athlete's heart is the term given to a constellation of cardiac structural, functional and electrical remodeling that accompanies regular athletic training. Due to the substantial phenotypic overlap between electrical and structural changes observed in the physiological athletic heart remodeling and pathological changes resulted from inherited or acquired cardiomyopathies, distinguishing between adaptive and maladaptive cardiovascular response to exercise is a challenging task.

Application of Artificial Intelligence in Early Detection of Lung Cancer presents the most up-to-date computer-aided diagnosis techniques used to effectively predict and diagnose lung cancer. The presence of pulmonary nodules on lung parenchyma is often considered an early sign of lung cancer, thus using machine and deep learning technologies to identify them is key to improve patients' outcome and decrease the lethal rate of such disease. The book discusses topics such as basics of lung cancer imaging, pattern recognition techniques, deep learning, and nodule detection and localization. In addition, the book discusses risk prediction based on radiological analysis and 3D modeling. This is a valuable resource for cancer researchers, oncologists, graduate students, radiologists, and members of biomedical field who are interested in the potential of AI technologies in the diagnosis of lung cancer.

Human-in-the-loop Learning and Control for Robot Teleoperation presents recent, research progress on teleoperation and robots, including human-robot interaction, learning and control for teleoperation with many extensions on intelligent learning techniques. The book integrates cutting-edge research on learning and control algorithms of robot teleoperation, neural motor learning control, wave variable enhancement, EMG-based teleoperation control, and other key aspects related to robot technology, presenting implementation tactics, adequate application examples and illustrative interpretations. Robots have been used in various industrial processes to reduce labor costs and improve work efficiency. However, most robots are only designed to work on repetitive and fixed tasks, leaving a gap with the human desired manufacturing effect.

Proteomics: A Promising Approach for Cancer Research provides an updated overview of scientific knowledge, achievements and findings in the field of cancer proteomics. The book discusses topics such as the use of proteomics in cancer biology and drug discovery, its role in surgical oncology, applications of mass spectrometry, target proteomics, single-cell proteomics, and next-generation proteomics. In addition, it discusses proteomics and phosphor-proteomics in cancer precision medicine; translation of proteomics research into clinical application; and challenges and future developments of the field. This will be a valuable resource for cancer researchers, oncologists, graduate students, and members of biomedical field who are interested in the potential of proteomics in cancer research and treatment. The field of cancer proteomics is very dynamic, with emerging trends related to clinical solutions developed in recent years, therefore this book's content helps readers get up-to-speed on the topic to easily apply learnings into their research or clinical practice.

Antimicrobial Dressings: The Wound Care Applications explores the literature surrounding the catalytic behavior of proteolytic enzymes immobilized together with nanoparticles. As numerous applications using proteolytic enzymes for debridement, silver as antibiotic and nanoparticles for enzyme immobilization were developed in the last years, this book explores interdisciplinary information combining nanotechnology, biotechnology and medicine and how it's still in early stages. The book adopts a holistic approach in a lifecycle context to evaluate their final feasibility, including industrial exploitability without disregard of the potential risks of enzymes and nanomaterials to human health and the environment.

Functional Foods and Chronic Disease: Role of Sensory, Chemistry and Nutrition explores the range of functional foods that are effective against a wide range of chronic diseases and addresses the impact of functional food bioactive compounds on organoleptic properties. Beginning with an introduction that details the key sensory and advanced instrumental methods essential for addressing the common problems associated with designing functional foods, the book also addresses the impact of aging and chronic diseases on sensory acuity as well as the effectiveness of functional foods in treating a wide range of chronic diseases. Sections highlight the need for acceptable functional foods for individuals suffering from a wide range of chronic diseases and contain practical recommendations for their development. Food scientists, nutritionists, dietitians, food product developers, food supplement producers, food ingredient developers, natural product scientists, herbalists, and pharmacists, as well as students studying related areas, will benefit from this important resource.

**Association of American Publishers (AAP) PROSE Award Finalist in Biomedicine and Neuroscience, 2024**Neurostimulation for Epilepsy: Advances, Applications, and Opportunities comprehensively reviews the diverse array of neurostimulation technologies currently in use and in development for the treatment of epilepsy. The book covers basic mechanisms of neurostimulation, technical characteristics of approved and investigational neurostimulation devices, clinical applications and programming considerations of these devices, and progress toward next-generation device technology. Leading experts in the field provide a contemporary appraisal of neurostimulation in epilepsy, one that highlights recent advances, outlines unanswered questions, and proposes future directions. Neurostimulation for Epilepsy: Advances, Applications, and Opportunities will be of high interest to clinical, basic, and translational researchers seeking to understand leading-edge applications of neurostimulation in epilepsy and to clinicians managing patients with epilepsy who are treated with implanted and external neurostimulation devices. This book will also be of interest to trainees, to physicians in other areas of neurology where neurostimulation is employed, such as Pain and Movement Disorders, and to general medical practitioners, neurobiologists, and engineers.

Revised edition of: Human reproductive and prenatal genetics / edited by Peter C.K. Leung, Jie Qiao. [2019].

Standardizing Pharmacology: Assays and Hormones, Volume Two in the Discoveries in Pharmacology series, presents selected articles from historic discoveries that are enhanced with commentary from contemporary scholars who present discussions on the importance of each chapter, along with an updated bibliography on the subject and contributions from a Nobel Prize winner and other pioneers in pharmacology. Academic and industry researchers in pharmacology and medicine, as well as advanced students will find this series a useful teaching tool and launch to new discoveries. Sections cover key discoveries in receptor theory, pharmacological methods and the development of hormone therapy, including J. Parascandola on the development of receptor theory, R.S. Yalow on radioimmunoassay, M. van Rossum and J.T L.A. Hurkmans on bioassays, M. Tausk on androgen therapy and C. Djerassi on oral contraceptives, with commentaries from experts such as T. Hökfelt and V.C. Jordan.

While there are many books that describe the theories and research of clinical psychology and psychiatry, there are few resources that provide structured simulations for rehearsal and advancement of the critical skills mental health professionals need in the field. Advanced Therapeutics, Clinical and Interpersonal Skills series aims to fill that gap. Authored and edited by leading experts, each volume in the series focuses on one subfield within mental health, providing concise and practical exercises for professionals. Each volume is based on an empirically based pedagogy that is structured, incremental, and tightly focused on the essential skills mental health professionals must acquire to obtain licensure/registration and work effectively with mental health patients. Practical Exercises for Mental Health Professionals is volume one in the series, focusing on providing concise and practical exercises for clinicians of any theoretical orientation and clinical role. These exercises include repairing alliance ruptures, motivating patients to address barriers to change, suicidal behavior strategies and establishing boundaries and limits. Each of these exercises have been tested by leading experts and clinics in the field.

Rehabilitation Robots for Neurorehabilitation in High, Low, and Middle Income Countries: Current Practice, Barriers, and Future Directions describes the state-of-art research of stroke rehabilitation using robot systems in selected High Income Countries (HICs) and Low and Middle Income Countries (LMICs), along with potential solutions that enable these technologies to be available to clinicians worldwide, regardless of country and economic status. The book brings together engineers and clinicians, offers insights into healthcare disparities, and highlights potential solutions to facilitate the availability and accessibility of more robot systems to stroke survivors and their clinicians worldwide, regardless of country and economic status.In addition, the book provides examples on how robotic technology is used to bridge rehabilitation gaps in LMICs and describes potential strategies for increasing the expansion of robot-assisted stroke rehabilitation across more LMICs.

Ultra-High Field Neuro MRI is a comprehensive reference and educational resource on the current state of neuroimaging at ultra-high field (UHF), with an emphasis on 7T. Sections cover the MR physics aspects of UHF, including the technical challenges and practical solutions that have enabled the rapid growth of 7T MRI. Individual chapters are dedicated to the different techniques that most strongly benefit from UHF, as well as chapters with a focus on different application areas in anatomical, functional and metabolic imaging. Finally, several chapters highlight the neurological and psychiatric applications for which 7T has shown benefits. The book is aimed at scientists who develop MR technologies and support clinical and neuroscience research, as well as users who want to benefit from UHF neuro MR techniques in their work. It also provides a comprehensive introduction to the field.

Unleashing the Potentials of Blockchain Technology for Healthcare Industries discusses blockchain and its adaptation in healthcare industries to provide a secured framework to safeguard healthcare data, both patient and hospital data. The book integrates key pillars of blockchain such as foundations, architecture, smart contracts, adoption, standards, service (BaaS), security, consensus algorithms, drug discovery process, among others, for fortifying the current practices in the healthcare industries. In addition, it offers solutions to the pressing issues currently being faced by the healthcare processes due to the COVD-19 pandemic. This will be a valuable resource for medical informaticians, researchers, healthcare professionals and members of the biomedical field who are interested in learning more about the potentials of blockchain in healthcare.