Böcker utgivna av Elsevier Science Publishing Co Inc

Gender Affirming Vaginoplasty is a novel reference of the latest research on those who present with Gender Dysphoria and desire surgery. The book describes the history of Gender Affirming Vaginoplasty (GAV), including social, legal, and ethical aspects of GAV, and explains updated Standards of Care. Users will find sections on preparation for surgery, different surgical techniques available (inclusive with the most recent developments), surgical results and complications, ways to solve complications, and finally, surgical procedures for persons who are requesting nonbinary genital surgery, and for those who are requesting reversal surgery.This is an unprecedented resource for all surgeons from various specialties already involved in gender-affirmative surgery and colleagues interested to gain state-of-the-art knowledge and experience in this field included plastic surgeons, urologists and gynecologists. Gender centers and trainees, scientists, researchers in transgender health, and organizations involved in trans health.

Recently, both researchers and consumers have shown strong and growing interest in craft beer, which is characterized by its small batches, local breweries, and unique varieties. Craft Beer: New Frontiers in Brewing Science provides a comprehensive picture of the craft beer market, history and legal definition, brewing processes, and the qualities and styles of the end product. It emphasizes traditional and innovative microbial resources involved in the fermentation process, as well as safety, nutrition, and emerging problems, such as the sustainability of the production process.Craft Beer: New Frontiers in Brewing Science is the first and only scientific text to comprehensively summarize this exciting field. Researchers and students in interested brewing science, as well as industry specialists from beer companies will all benefit from this unique resource.

Open Radio Access Network (O-RAN) Systems Architecture and Design, 2nd edition, gives a jump start to engineers developing O-RAN hardware and software systems, providing a top-down approach to O-RAN systems design from an author with a silicon, software, and system background. It gives an introduction into why wireless systems look the way they do today before introducing relevant O-RAN and 3GPP standards. The remainder of the book discusses hardware and software aspects of O-RAN system design, including dimensioning and performance targets, and some practical use case examples that include 5G advanced topics. This edition includes comprehensive updates in key areas such as postquantum security and radio unit design. Additionally, it addresses emerging 5G advanced topics, including Industrial & URLLC, nonterrestrial networking, the role of artificial intelligence, 5G reduced capabilities for IoT, and self-organizing networks.

Cancer, a multifaceted disease, remains the leading cause of death worldwide. Ongoing research and technological advancements are continually improving the human understanding of newer treatment options. This book series aims to provide wide-ranging insights into the current landscape of cancer research, highlighting the recent advancements, current challenges, and future directions. Cancer varies widely in its formation, microenvironment, location in the body, associated risk factors, detection methodology, and treatment approaches. Early detection and prevention through lifestyle changes, regular screenings, and the awareness of symptoms are crucial for improving outcomes and survival rates. In this book series, the main focus is on trending topics, like new drug delivery, diagnostics, biomarkers, and preclinical and clinical developments in cancer research. Nanotechnology has emerged as a transformative approach in medicine, particularly in the areas of targeted drug delivery systems, imaging, and diagnostics to enhance the therapeutic efficacy and minimize adverse effects in cancer therapy. Advances in pharma, medical device, and diagnostic research, including the development of Trojan-horse therapies and precision treatments/assay kits, continue to enhance the effectiveness of cancer care over the past few decades. A total of five books are covered in this series: Drug Delivery Landscape in Cancer Research (Vol. 1)Biomarker Landscape in Cancer Research (Vol. 2)Diagnostic Landscape in Cancer Research (Vol. 3)Preclinical Landscape in Cancer Research (Vol. 4)Clinical Landscape in Cancer Research (Vol. 5) By integrating basic, applied, and innovative science concepts, this book series fosters a deeper understanding of the disease and paves the way for the development of more effective strategies. This book series serves as a valuable resource for students, researchers, regulators, and clinicians interested in understanding the complexities of cancer and the innovative approaches researched to combat this deadly disease. Nonetheless, continuous interdisciplinary, cross-country collaborations and cross-science innovation strategies are essential to further reduce the global cancer burden.

Biomedical and Clinical Cryogenics: Theory, Current Technology Advances, and Future Perspectives presents the complexity of cryogenic engineering applications in both medical and clinical settings. The book demonstrates both a comprehensive and up-to-date understanding of ongoing, new applications and their cutting-edge breakthroughs within the biomedical engineering sector. It contributes to the rapidly emerging and expanding field of cryogenics by emphasizing the complexity of associated mechanisms and interactions. In six chapters, this book collects, investigates, and critically discusses state-of-the-art cryogenic practices, along with the challenges and perspectives of the most common applications.By using cryogenics sciences, new milestones in medicine and human-life expectancy can be significantly increased. Since this is highly interdisciplinary content, this book is a valuable resource for biomedical engineers, health professionals, scientists, researchers, students, and all those who wish to broaden their knowledge in the allied field.

Nanotechnology of Veterinary Medicine and Livestock Production compiles the most impactful emerging research on the use of nanotechnology in animal sciences. This novel data, methods, and technologies will improve animal health, welfare, production, and nutrition, and will have implications for the future of human health, disease control, and food safety. Authored by a renowned animal toxicologist, this book introduces the history of nanotechnology in animal science before delving into its interdisciplinary applications. Central chapters explore nanomaterials in animal disease treatment, nanovaccine development, nanotechnology in animal nutrition and production, and applications for antibiotic-based therapies.Concluding chapters summarize the risks of these novel technologies, their challenges, and opportunities in various animal science sectors. This is an essential resource for researchers, clinicians, and animal scientists seeking information on cutting edge nano- and biotechnological advancements.

Human- Centric Integration of Next Generation Data Science and Blockchain Technology: Advancing Society 5.0 Paradigms focuses on the current technological landscape, addressing the evolving integration of data science and blockchain within the context of Society 5.0. This comprehensive resource explains the convergences between data science, blockchain, and the human-centric vision of Society 5.0, while also filling the gap in understanding and navigating this transformative intersection with recent shifts towards more decentralized and data-driven paradigms.The book introduces the concept of Society 5.0, examining the historical context, and outlines the evolving technological landscape shaping our interconnected future. It discusses the fundamental principles of data science, from data collection and preprocessing to exploratory data analysis and explains the transformative impact of data science and blockchain across industries such as healthcare, finance, education, and transportation. This book is essential to understanding and shaping the future of technology and society from decentralized solutions to predictive analytics/ emerging technologies.

Healthcare Frontiers in the Metaverse: Innovations and Impacts provides a deeper comprehension of the metaverse's revolutionary effects on patient care, medical education, and operational procedures in the healthcare sector. The book Includes both the fundamentals of patient experience, provider practices, and the overall framework of the healthcare business as the democratisation of medical education through virtual simulations and the individualised care enabled by AI-driven diagnostics. In 14 chapters "Healthcare Frontiers in the Metaverse: Innovations and Impacts" leads the reader to an introduction to, definition, elements, treatment and diagnostic in healthcare in metaverse, the next evolution in social connection and the successor to the mobile internet. It describes the role of robots and give a view on the future scope and challenges. " Exploration of Healthcare in Metaverse: Innovations and Impacts" serves as a road map for technologists and policymakers influencing the direction of healthcare as well as a help book for medical practitioners integrating metaverse technologies into their practice.

Green Microbiology: Sustainability, Climate Change, Food, and Water provides a comprehensive overview of the principles and applications of green microbiology.The book introduces readers to the various ways in which microbes can be used in sustainable development, including in areas such as climate change, food production, bioenergy, bioremediation, and water treatment. The book also discusses the social, economic, and environmental impact of green microbiology, as well as the business and future trends in this field. Thus, this work also contributes to meeting the 2030 Sustainable Development Goals (SDGs) adopted by the United Nations in 2015, as it covers the various ways in which green microbiology can contribute to the achievement of these goals.Edited by two highly qualified and experienced professionals in the field of industrial microbiology and environmental science, with a particular expertise in the intersection between food processing and food microbiology, this book is a valuable resource for students, researchers, and professionals in the field, helping to solve the problems of a lack of comprehensive resources and a lack of understanding of the role of microbes in sustainable development.

Control of Underactuated Mechanical Systems: Stabilization and Limit Cycle Generation clearly explains stabilization and limit cycle generation in underactuated mechanical systems (UMS), addressing control design challenges and demonstrating concepts through real-time experiments. The book begins with advancements in UMS, introducing key concepts such as stabilization and limit cycle generation, supported by literature examples. It then focuses on the inertia wheel inverted pendulum, presenting a detailed discussion. The second part tackles stabilization, offering various control solutions validated through numerical simulations and real-time experiments. The final part addresses stable limit cycle generation, detailing three proposed control solutions and their validation through different case studies. This book is a valuable resource for PhD and Master students, engineers, researchers, and educators. It provides guidance in robotics and automatic control, utilizing a simplified methodology for controlling underactuated mechanical systems.

An Overview of FDA Regulated Products: From Drugs and Cosmetics to Food and Tobacco, Second Edition is fully updated to reflect recent advances in science and technology and new laws and regulations. Breakthroughs in cellular and gene therapy, immunotherapy, precision medicine, and digital health are changing the face of healthcare and regulation. The updates brought about by the 21st Century Cures Act and subsequent PDUFA Reauthorizations, as well as signing into law the "Modernization of Cosmetic Regulation Act of 2022," which will transform FDA’s oversight of cosmetics, are fully reflected in all chapters of the book. This book provides graduate students and industry professionals with comprehensive information on approval processes with the FDA and other country regulation organizations. Regulatory science professionals working with not only drugs, but biologics, medical devices, food and additives, cosmetics, veterinary products, and tobacco will benefit from this comprehensive overview of the regulatory environment.

Enzymatic Production of Oligosaccharides: From Basic Research to Industrial Production, a volume in the Foundations and Frontiers of Enzymology series, covers the enzymes used for the extraction, synthesis, or modification of oligosaccharides, the biochemical properties of those enzymes, and potential technological applications. The book is divided into three parts, the first of which shares the fundamentals on the enzymatic synthesis of oligosaccharides. The book then explores the enzymatic production of oligosaccharides, considering a range of different oligosaccharides and production processes. Final sections cover the technological properties of oligosaccharides and potential applications across the chemical, biochemical, biotechnology, and food industries.This is a useful reference for researchers working with oligosaccharides across biochemistry, enzymology, biotechnology, food chemistry and related fields.

Cholecystokinin: From Gallbladder to Cognition and Beyond covers the biology, physiology and pathophysiological roles of cholecystokinin (CCK) peptides. It begins with a historical overview before providing in-depth chapters into the biology of CCK, from biogenesis to cell expression, including intestinal and extraintestinal endocrine cells, and the central and peripheral nervous system, and receptor function. CCK phylogenesis is explored across various species, including fish, birds, insects and amphibians. The physiology of CCK covers intestinal CCK secretion, the gallbladder and pancreas, and the role of CCK in the gut-brain axis, gastrointestinal motor function, appetite regulation, and cardiovascular function. Methods used for CCK research are also discussed. A number of chapters then cover the roles of CCK in various diseases, including metabolic diseases, tumors, psychiatric illness, the immune system and nociception, as well as potential therapeutic approaches targeting CCK receptors.Cholecystokinin: From Gallbladder to Cognition and Beyond is a volume in the Molecular Mediators in Health and Disease book series, and acts as a fundamental reference on all biological and clinical aspects of CCK. This book is ideal for researchers interested in learning more about the role of CCK and its impact across health and disease.

Nano-bioinoculants: Smart Tools for Modern Agriculture discusses the interactions between nanoparticles and soil-plants-microbiome systems in a single-volume book designed to guide improvements in sustainable agriculture i.e. plant production and soil health. Past practices for the application of pesticides and chemical fertilizers have reduced the beneficial microbial diversity and soil fertility essential for optimal crop yield and overall plant health. As a result, developing innovative approaches to plant/soil health maintenance, bioremediation process, and stress management is advancing. Plant protection methods are increasingly being tailored to improve sustainable precision results, reduce environmental impact, and to target specific plant health challenges. Nano-bioinoculants: Smart Tools for Modern Agriculture explains nanoparticles and beneficial microbes and their impact on soil microbiomes, soil fertility restoration, remediation of contaminated soil, and plant health. It also highlights nanoparticles and bioinoculants in stress management, plant growth, and productivity, as well as covering the potentially toxic effect of nanoparticles on humans and the environment. This volume in the Nanomaterial-Plant Interactions series explores the potential of nano-biotechnology for better agronomic performance and sustainability.

The study of one-shot devices such as automobile airbags, fire extinguishers, or antigen tests, is rapidly becoming an important problem in the area of reliability engineering. These devices, which are destroyed or must be rebuilt after use, are a particular case of extreme censoring, which makes the problem of estimating their reliability and lifetime challenging. However, classical statistical and inferential methods do not consider the issue of robustness. Statistical Modeling and Robust Interference for One-shot Devices offers a comprehensive investigation of robust techniques of one-shot devices under accelerated-life tests. With numerous examples and case studies in which the proposed methods are applied, this book includes detailed R codes in each chapter to help readers implement their own codes and use them in the proposed examples and in their own research on one-shot device-testing data. Researchers, mathematicians, engineers, and students working on accelerated-life testing data analysis and robust methodologies will find this to be a welcome resource.