Böcker av Trevor Cornfield

Alzheimer's disease is one of the most common neurodegenerative diseases, and it is characterized by abnormal protein deposition in the brain. It is the most prevalent type of dementia. It has two primary causes. It may be caused by the extracellular accumulation of abnormal amounts of amyloid beta (Aβ) proteins which lead to accumulation of amyloid plaques. This disease may also occur due to intracellular accumulation of neurofibrillary tangles. In both these cases, the plaques and tangles formed by these proteins disrupt brain nerve cell transmission and affect the neuronal functioning and connectivity which leads to loss of brain function. Alzheimer's disease affects memory and thinking abilities of a person. Significant behavioral and psychological symptoms such as sleep changes are also observed. The current treatments available for this disease focus on improving symptoms of memory loss and problems with thinking and reasoning. This book is a valuable compilation of topics, ranging from the basic to the most complex advancements related to the causes, diagnosis and treatment of Alzheimer's disease. It aims to shed light on some of the unexplored aspects and recent researches on this disease. This book will serve as a valuable source of reference for students, researchers and medical practitioners.

Alzheimer's disease (AD) refers to a type of neurodegenerative disease that typically begins slowly and worsens over time. The most usual symptom is trouble remembering recent events. Various other symptoms can also occur with the progression of the disease, such as loss of motivation, behavioral issues, mood swings, problems with language, self-neglect and disorientation. As the health of the patient deteriorates, they frequently withdraw from society and family. There are numerous environmental and genetic risk factors that contribute to the development of this disease. An allele of the apolipoprotein E (APOE) is the most powerful genetic risk factor. There are several other risk factors, such as high blood pressure, a history of head injury and clinical depression. There are no treatments that can reverse or stop the development of the disease, while some can temporarily alleviate symptoms. This book aims to understand the clinical perspectives of Alzheimer's disease. It aims to shed light on some of the unexplored aspects of this disease. Those with an interest in this field would find this book helpful.