Böcker av Octavia Settle

antineoplastic agents are used to treat several types of cancer. They have the potential to alkylate many molecules, including proteins, RNA and DNA, which is the primary cause for their anti-cancer effect. This book is a compilation of chapters that discuss the most emerging trends in the field of anticancer drugs. It presents researches and studies performed by experts across the globe. This book is an invaluable resource for cancer researchers, medicinal chemists and other biomedical scientists involved in the development of new anticancer therapies.

Anticancer drugs refer to drugs that are used for treating cancerous or malignant diseases. They are classified into several categories, including antimetabolites, hormones, alkylating agents and natural products. Preclinical research, clinical research and post-clinical research are the three primary steps in the development of a novel drug. Clinical trial evaluation, in vivo confirmation, and in vitro cytotoxicity on cancer cells are the major assessment methods used while creating an anticancer drug. The evaluation of cytotoxicity towards cancer cell lines is a popular method for discovering anticancer agents. New cancer drugs can be discovered in a variety of ways including testing of animals, plants and fungi, understanding the chemical structure of a drug target, unintentional discovery, developing drugs that are similar to existing drugs, and researching the biology of cancer cells. This book unravels the recent studies on anticancer drug discovery and development. Those in search of information to further their knowledge will be greatly assisted by it.

Anticancer drugs are utilized in the treatment of cancerous growth or malignancies. These drugs can be administered in isolation, or they can be given along with other treatments, like radiation therapy or surgery. The development of novel anticancer drugs is a lengthy process that includes acquiring new compounds, testing for antitumor activity, formulation and manufacturing, animal toxicology, and lastly assessing the compound's toxicity as well as antitumor activity in humans. There are various medications that are utilized as anticancer drugs, such as L-asparaginase, amsacrine, platinum-based drugs and hydroxyurea. Preclinical models such as cell line model systems may be especially useful in predicting anticancer drug response. It also helps to understand the mechanisms of drug action in situations when clinical samples are unavailable, or the cost of obtaining clinical samples for studying drug response is expensive. The aim of this book is to present researches that have transformed anticancer drug development. Those in search of information to further their knowledge will be greatly assisted by this book.