Böcker av Heidi Hamlin

Non-alcoholic fatty liver disease (NAFLD) refers to a heterogeneous condition with an extensive range of clinical presentations and disease severity. People who suffer from this disease are observed to consume little or no alcohol, and have excessive fat stored in their liver cells. Damage to the liver under this condition is caused by the generation of oxidative metabolites and by the translocation of gut-derived endotoxin. These processes result in cellular injury and stimulation of the inflammatory responses facilitated by a range of molecules. The injury develops with impairment in tissue regeneration and extracellular matrix turnover which results in causing cirrhosis and fibrogenesis. Some of the major risk factors for this disease are obesity, insulin resistance and diabetes. This book explores all the important translational and clinical researches on non-alcoholic fatty liver disease in the modern day. It presents researches and studies performed by experts across the globe. The extensive content of this book provides the readers with a thorough understanding of the subject.

Non-alcoholic fatty liver disease (NAFLD) refers to a group of diseases including inflammatory non-alcoholic steatohepatitis (NASH), hepatic cirrhosis, simple hepatic steatosis and developing stages of fibrosis. It is also connected to other medical conditions such as obesity, diabetes, metabolic syndrome and cardiovascular disease. It can be diagnosed through various methods such as by studying the medical history, conducting a physical examination and through different tests. A few of the tests which can help in the diagnosis of non-alcoholic fatty liver disease are blood tests, imaging tests and liver biopsy. Disease progression differs from individual to individual and is related to a variety of risk factors. A few of the major risk factors linked with NAFLD are hepatic oxidative stress, reduced very low-density lipoprotein secretion, imbalanced diet and lifestyle, and influx of free fatty acids to the liver from adipose tissue due to insulin resistance. The management of NAFLD can be done through reducing weight and improving physical activity. This book provides significant information to help develop a good understanding of non-alcoholic fatty liver disease. It aims to shed light on some of the unexplored aspects of this disease. The extensive content of this book provides the readers with a thorough understanding of this medical condition.