Böcker av Alfred Galswells

Multiple sclerosis (MS) refers to a neurodegenerative disease. It has been characterized as a chronic immune-mediated disease, with strong neurodegenerative mechanisms in the progressive phase of the disease. Progressive multiple sclerosis is an advanced form of MS, categorized through the slow accumulation of disability over time without relapses. It is often manifested as a neurological development of one or more symptoms. Secondary progressive MS (SPMS) develops after an early relapsing course of the disease, whereas primary progressive MS (PPMS) develops gradually over time. Inflammation can also occur in PMS as aggregates of inflammatory cells in the meninges that includes a follicle-like presence. The diagnosis of PMS might be challenging, as it may remain unnoticed by physicians or patients for a long period. There are presently no recognized therapies for progressive forms of MS. This book aims to understand the clinical perspectives of multiple sclerosis. Some of the diverse topics covered herein address the causes, diagnoses and management of multiple sclerosis. The readers would gain knowledge that would broaden their perspective in this area.

Multiple sclerosis (MS) is referred as the most prevalent demyelinating disease, where the insulating covers of nerve cells in the spinal cord and brain are destroyed. This injury impairs the capability of the parts of nervous system to transmit signals. This leads to a variety of signs and symptoms such as mental, physical and occasionally psychiatric issues. Problems with coordination or sensation, double vision, muscle weakness and blindness in one eye are some of the major symptoms. The etiology of MS is unknown; but numerous risk factors have been linked to its pathogenesis, comprising a link between environmental agents and genetic vulnerability. The breakdown of myelin sheaths of neurons, creation of lesions in the central nervous system and inflammation are the three basic characteristics of MS. This book is compiled in such a manner, that it will provide in-depth knowledge about the etiology and pathophysiology of multiple sclerosis. It aims to shed light on some of the unexplored aspects of this disease. Researchers and students in this field will be assisted by this book.